Lungs News and Research

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What is the efficacy of aerosol treatment for SARS-CoV-2 infection?

In a new study, researchers assessed the efficacy of the scFv76 antibody against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung damage.

21 Sep 2022

Common genetic variants of APOE associated with COVID mortality

It may be the most baffling quirk of COVID: What manifests as minor, flu-like symptoms in some individuals spirals into severe disease, disability, and even death in others.

21 Sep 2022

Prophylactic administration of SARS-CoV-2 specific immunoglobulin Y generated in chicken eggs displays protective effects in infected mice

A new study characterized and tested the antibody activity of SARS-CoV-2-specific immunoglobulin Y (IgY) derived from the eggs laid by chickens immunized with recombinant SARS-CoV-2 receptor binding domain (RBD) protein.

21 Sep 2022

Study: Life-threatening blood clots remain for at least 49 weeks after COVID-19

COVID-19 infection increases the risk of potentially life-threatening blood clots for at least 49 weeks, according to a new study of health records of 48 million unvaccinated adults from the first wave of the pandemic.

21 Sep 2022

Clearing pollution helps clear the fog of aging — and may cut the risk of dementia

During the past decade, a growing body of research has shown that air pollution harms older adults' brains, contributing to cognitive decline and dementia. What hasn't been clear is whether improving air quality would benefit brain health.

20 Sep 2022

Regular fish oil consumption found effective in preventing severe COVID-19 outcomes

In a new study, researchers investigated whether regular fish oil use decreased the risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

20 Sep 2022

Molecular engineered low-cost highly effective RBD-based COVID vaccine

In a recent study posted to the bioRxiv* preprint server, an international team of researchers developed a second-generation severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor binding domain (RBD) antigen (RBD-J6) by molecular engineering with two additional amino acid (aa) substitutions (S383D and L518D mutations) in a hydrophobic cryptic RBD core epitope to enhance stability and expression against SARS-CoV-2 variants of concern (VOCs).

19 Sep 2022

Researchers reveal native 3D structure of the ciliary base for the first time

Cilia are small hair-like organelles that extend from cells and perform many functions, including motility and signaling.

19 Sep 2022

New white paper outlines the issues surrounding delays in diagnosing interstitial lung diseases

A steering committee of pulmonary experts and primary care physicians (PCPs) released today a white paper outlining the issues surrounding delays in diagnosing interstitial lung diseases (ILDs) like pulmonary fibrosis (PF).

19 Sep 2022

Milken Institute and ATF announce new Request for Proposals to advance understanding of sarcoidosis

The Milken Institute Center for Strategic Philanthropy, in partnership with the Ann Theodore Foundation (ATF), is pleased to announce a new Request for Proposals (RFP) focused on understanding the underlying biology of sarcoidosis, an immune dysregulation condition.

19 Sep 2022

Researchers identify a genetic defect in alveolar macrophages that causes lung disease

New discovery on the causes of PAP lung disease can also offer solutions for treating obesity and heart disease. The research group of Associate Professor Alexander Mildner at the University of Turku, Finland, identified a genetic defect that causes the accumulation of lipids in the pulmonary alveoli.

19 Sep 2022

Smartphones can detect blood oxygen saturation levels down to 70%, study shows

First, pause and take a deep breath. When we breathe in, our lungs fill with oxygen, which is distributed to our red blood cells for transportation throughout our bodies. Our bodies need a lot of oxygen to function, and healthy people have at least 95% oxygen saturation all the time.

19 Sep 2022

Research examines the roles of cytokines during SARS-CoV-2 infection in rhesus macaques

In a recent study posted to the bioRxiv* preprint server, researchers in the United States assessed the role of two cytokines, interferon-gamma (IFN-γ) and interleukin-10 (IL-10), in regulating immune cell responses and inflammation early during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in rhesus macaques.

18 Sep 2022

An improved COVID-19 vaccine shows promise against Omicron in experimental models

In a recent study published in the journal Science Translational Medicine, researchers in the United States designed a bivalent coronavirus disease 2019 (COVID-19) vaccine on the messenger ribonucleic acid (mRNA) platform.

18 Sep 2022

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

If a secretion in the lungs’ alveoli is not cleared regularly, breathing difficulties can develop. In a study published in Science Immunology, a team led by Alexander Mildner and Achim Leutz has now explained the pivotal role of the transcription factor C/EBPb in this process.

16 Sep 2022

Lab experiments add further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19's viral pathogenesis - a theory that was posited two years ago by a team of researchers at the Department of Energy's Oak Ridge National Laboratory.

16 Sep 2022

One year later, 40% of patients with COVID pneumonia still had lung problems

A recent study published in the journal Respiratory Research found impaired lung function and dyspnea amongst severe COVID-19 pneumonia survivors one year post-infection. Meanwhile, many COVID-19 patients developed fibrotic-like sequelae as an aftermath of the infection-associated mild or severe pneumonia.

15 Sep 2022

Lungs News and Research

What is the efficacy of aerosol treatment for SARS-CoV-2 infection?

Common genetic variants of APOE associated with COVID mortality

Prophylactic administration of SARS-CoV-2 specific immunoglobulin Y generated in chicken eggs displays protective effects in infected mice

Study: Life-threatening blood clots remain for at least 49 weeks after COVID-19

Clearing pollution helps clear the fog of aging — and may cut the risk of dementia

Regular fish oil consumption found effective in preventing severe COVID-19 outcomes

Molecular engineered low-cost highly effective RBD-based COVID vaccine

Researchers reveal native 3D structure of the ciliary base for the first time

New white paper outlines the issues surrounding delays in diagnosing interstitial lung diseases

Milken Institute and ATF announce new Request for Proposals to advance understanding of sarcoidosis

Researchers identify a genetic defect in alveolar macrophages that causes lung disease

Smartphones can detect blood oxygen saturation levels down to 70%, study shows

Research examines the roles of cytokines during SARS-CoV-2 infection in rhesus macaques

An improved COVID-19 vaccine shows promise against Omicron in experimental models

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

Lab experiments add further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis

One year later, 40% of patients with COVID pneumonia still had lung problems

Discovery of 380-million-year-old heart sheds new light on the evolution of our bodies

New immunotherapy approach may lead to an effective treatment for fibrosis

What is the effect of the Omicron variant on olfaction?

The ultimate guide to lung research tools and protocols eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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