Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Targeting mutant p53 specific binding protein could lead to new therapeutic strategies for cancer patients

Research by Rutgers Cancer Institute of New Jersey investigators shows the targeting of a binding protein of mutant p53 known as Rac1 could lead to new therapeutic strategies for patients whose cancer carries mutations in the p53 gene.

22 Sep 2017

Researchers identify new genetic test to help predict cancer recurrence

Researchers have discovered a new genetic test which could help predict cancer recurrence - paving the way for more precise, personalized treatments.

21 Sep 2017

Study identifies slowly proliferating and highly invasive melanoma cells

A study conducted at The Wistar Institute has led to the identification of a slowly proliferating and highly invasive melanoma cell subpopulation, characterized by production of a protein associated with invasive behavior. The research was published in the journal Oncogene.

21 Sep 2017

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

University of Maryland School of Medicine researchers are investigating a new approach to treat high-risk soft-tissue sarcomas by combining two immunotherapy drugs with radiation therapy to stimulate the immune system to destroy the main tumor as well as leftover microscopic cancer cells that may seed other tumors.

20 Sep 2017

UTSW receives $34 million CPRIT award for cancer research and faculty recruitment

The Cancer Prevention and Research Institute of Texas has awarded UT Southwestern researchers more than $34 million for cancer research and faculty recruitment, including support for programs in pancreatic cancer, lung cancer, breast cancer, and melanoma.

19 Sep 2017

Study: Genomic profiling could help identify effective treatments for pediatric gliomas

The largest genomic profiling study ever conducted into a type of brain tumor known as glioma in children has identified genetic alterations in 96% of cases. As reported in The Oncologist, this genetic information could help to identify the most effective treatments for specific cases of glioma, hopefully improving the prognosis for what is currently the leading cause of death for children with cancer in the US.

18 Sep 2017

Research uncovers new target for therapy, diagnosis, and prognosis of colon cancer

Genetic research conducted at LSU Health New Orleans School of Medicine and Stanley S. Scott Cancer Center demonstrated for the first time that a novel protein can cause normal cells in the lining of the colon to become malignant, grow and spread, as well as take on the characteristics of stem cells.

12 Sep 2017

Prostate Cancer Awareness Month: Myriad Genetics working to educate public about hereditary cancer risk assessment

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, is working to educate the public about hereditary cancer risk assessment and testing during Prostate Cancer Awareness Month this September.

11 Sep 2017

Cold Spring Harbor Laboratory Press releases new book on Cell Polarity

Cold Spring Harbor Laboratory Press announced the release of Cell Polarity, available on its website in hardcover format.

7 Sep 2017

Seeing the full picture, real-time analysis of live-cells

Every cell is a miniature factory taking in raw material (extracellular signals) and processing it to produce something (a biological response). But unlike a factory that can be easily tweaked to run at steady-state and look the same from day to day, cells are dynamic.

From Sartorius 7 Sep 2017

New microfluidic device offers insights on cancer metastasis

As cancer grows, it evolves. Individual cells become more aggressive and break away to flow through the body and spread to distant areas.

7 Sep 2017

Study describes link between key melanoma signaling pathway and novel class of drugs

Results of a study by The Wistar Institute have described a correlation between a key melanoma signaling pathway and a novel class of drugs being tested in the clinic as adjuvant therapy for advanced melanoma, providing useful information for a more effective use of this type of treatment.

7 Sep 2017

Researcher develops bone marrow models to study hematological and musculoskeletal diseases

For her research on the development of hematological and musculoskeletal disorders, Dr. Cornelia Lee-Thedieck, scientist at Karlsruhe Institute of Technology, is awarded an ERC Starting Grant: The European Research Council decided to fund her project "bloodANDbone" with EUR 1.5 million for five years. At KIT's Institute of Functional Interfaces, Lee-Thedieck develops models of the human bone marrow to study the regeneration of blood and bone by stem cells and how this regeneration is disturbed in diseases like leukemia or bone metastases.

6 Sep 2017

Scientist receives NIH grant to investigate tumor microenvironment from relatively new context

Cancer metastasis – the spread of disease from the original site to a distant organ – remains a major challenge in treating cancer and a main cause of morbidity and mortality.

6 Sep 2017

Mayo Clinic research clarifies relationship between two genes that fuel neuroblastoma spread

For the first time, Mayo Clinic researchers and colleagues present data on how nervous system tumors, called neuroblastomas, spread. Their paper, published in Cancer Cell, clarifies the relationship between two genes that fuel the aggressive spread of neuroblastomas.

1 Sep 2017

‘Liquid biopsies’ may help predict prognosis of early-stage lung cancer patients

Cancer cells obtained from a blood test may be able to predict how early-stage lung cancer patients will fare, a team from the University of Michigan has shown.

30 Aug 2017

Photoacoustic technique uses lasers to create detailed ultrasound images in live animals

Researchers have developed a photoacoustic imaging technique that uses lasers to create detailed ultrasound images in live animals. The method allows for complete internal body scans with enough spatiotemporal resolution to see active organs, circulating cancer cells, and brain function.

30 Aug 2017

Scientists develop new chimeric antibody to treat malignant cancers in dogs

Scientists have developed a new chimeric antibody that suppresses malignant cancers in dogs, showing promise for safe and effective treatment of intractable cancers.

26 Aug 2017

NIH grant for CWRU professors could enable new directions for cancer immunotherapies

Nicole Steinmetz, PhD, Associate Professor of Biomedical Engineering, Radiology, member of the Case Comprehensive Cancer Center and the Center for RNA Science and Therapeutics in the Division of General Medical Sciences at Case Western Reserve University School of Medicine and the holder of the George J. Picha Designated Professor in Biomaterials, has received a major grant from the National Institutes of Health to help understand how a virus-like particle from plants stimulates potent anti-tumor responses.

26 Aug 2017

Novel nanolaser can serve as super-bright probe to detect and kill metastasized cancer cells

A nanolaser known as the spaser can serve as a super-bright, water-soluble, biocompatible probe capable of finding metastasized cancer cells in the bloodstream and then killing these cells, according to a new research study.

22 Aug 2017

Metastasis News and Research

Further Reading

Targeting mutant p53 specific binding protein could lead to new therapeutic strategies for cancer patients

Researchers identify new genetic test to help predict cancer recurrence

Study identifies slowly proliferating and highly invasive melanoma cells

Researchers explore new combination approach to treat high-risk soft-tissue sarcomas

UTSW receives $34 million CPRIT award for cancer research and faculty recruitment

Study: Genomic profiling could help identify effective treatments for pediatric gliomas

Research uncovers new target for therapy, diagnosis, and prognosis of colon cancer

Prostate Cancer Awareness Month: Myriad Genetics working to educate public about hereditary cancer risk assessment

Cold Spring Harbor Laboratory Press releases new book on Cell Polarity

Seeing the full picture, real-time analysis of live-cells

New microfluidic device offers insights on cancer metastasis

Study describes link between key melanoma signaling pathway and novel class of drugs

Researcher develops bone marrow models to study hematological and musculoskeletal diseases

Scientist receives NIH grant to investigate tumor microenvironment from relatively new context

Mayo Clinic research clarifies relationship between two genes that fuel neuroblastoma spread

‘Liquid biopsies’ may help predict prognosis of early-stage lung cancer patients

Photoacoustic technique uses lasers to create detailed ultrasound images in live animals

Scientists develop new chimeric antibody to treat malignant cancers in dogs

NIH grant for CWRU professors could enable new directions for cancer immunotherapies

Novel nanolaser can serve as super-bright probe to detect and kill metastasized cancer cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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