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Low-intensity ultrasound therapies may help rebuild stronger knees

Low-intensity ultrasound therapies may one day rebuild stronger knees following injury or surgery, thanks to research by Dr. Anu Subramanian at The University of Alabama in Huntsville (UAH) that's being supported by the National Institutes of Health.

7 Dec 2022

Scientists report the in vitro production of infectious Plasmodium falciparum sporozoites

Scientists from Sanaria Inc., and collaborators at multiple institutions publish results in Nature reporting "In vitro production of infectious Plasmodium falciparum sporozoites."

7 Dec 2022

Understanding why respiratory infections are more common in the winter

Researchers investigate the role of extracellular vesicles in the innate nasal mucosal response to several respiratory viruses.

6 Dec 2022

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Researchers evaluated blood plasma proteins to identify new targets for COVID-19 treatment approaches and prevent complications associated with severe illness.

5 Dec 2022

Researchers develop a polyvalent lipid nanoparticle mRNA vaccine against Monkeypox virus

Researchers developed an mRNA technology-based vaccine candidate against the monkeypox virus and evaluated its immunogenicity in animal models.

5 Dec 2022

How two structurally different lemon pectins modulate the gut microbiota

A diet containing fruits and vegetables contains pectins (plant polysaccharides). Pectin cannot be metabolized by mammalian cells in the gastrointestinal tract but is fermented by the gut microbiota in the colon, where short-chain fatty acids (SCFAs) are released. Previous studies have examined pectin's prebiotic properties.

4 Dec 2022

Mucosal IgA fused nanobody as a non-invasive, cost-effective prophylaxis and therapeutic option against major SARS-CoV-2 variants

Researchers from the United States developed an affordable, non-invasive, inhalable prophylactic treatment consisting of immunoglobulin (Ig) A fused nanobodies against the SARS-CoV-2 Omicron variant.

2 Dec 2022

Exploring the effects of dietary fiber on gut microbiome and inflammatory diseases

Researchers reviewed how dietary fibers modulate the composition and function of gut microbiota.

2 Dec 2022

Collaborative work unravels hidden molecular secrets of age-related diseases

Insilico Medicine, a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, and the University of Copenhagen announced today the release of the first batch of results from the collaborative work directed to perform multi-omics-based analyses in the context of age-related diseases using an AI-driven target and drug discovery pipeline.

2 Dec 2022

Novel prefusion S antigen designed by the mutation of the SARS-CoV-2 Spike protein’s trimeric structure

Researchers mutated the SARS-CoV-2 spike protein's trimeric structure to design a novel prefusion S antigen, S2D14.

1 Dec 2022

The requirement for Fc effector functions to protect against SARS-CoV-2 infection

Researchers determined which specific fragment crystallizable effector functions protect against SARS-CoV-2 infection, especially its emerging variants.

1 Dec 2022

Impact of COVID-19 on sperm quality

Researchers examined the effect of coronavirus disease 2019 (COVID-19) on sperm quality.

1 Dec 2022

Study provides a framework to guide the development of variant-resistant SARS-CoV-2 vaccines

Latest research findings show that vaccine-elicited neutralizing antibodies against SARS-CoV-2 are mostly directed against one of the two main domains of the viral entry machinery.

30 Nov 2022

New urinary biomarkers could help monitor potential abuse of emerging synthetic cannabinoids

A team of scientists from the National University of Singapore (NUS) has successfully identified the urinary biomarkers of an emerging subclass of synthetic cannabinoids, called OXIZID, to monitor potential abuse.

30 Nov 2022

Unique scaffolding material shows significant promise in the treatment of spinal cord injury

Unique new material developed at University of Limerick in Ireland has shown significant promise in the treatment of spinal cord injury.

29 Nov 2022

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Researchers report that a gut microbial catabolite could reduce the cardiometabolic disease burden in mice.

29 Nov 2022

Antioxidant and anti-inflammatory properties of Stingless bee-derived propolis against acne

Researchers explore the anti-acne, antioxidant, and anti-inflammatory properties of Stingless bee (Tetragonula biroi)-derived propolis.

29 Nov 2022

Endogenous system may be responsible for delayed onset of diabetic retinopathy

About one third of patients with diabetes mellitus (DM) develop diabetic retinopathy (DR), a leading cause of blindness in working-age individuals. DR typically develops after many years of DM, and some patients do not develop DR for more than 50 years.

29 Nov 2022

Pediatric acute myeloid leukemia genetic subtypes with poor outcomes show increased inflammatory cytokine signaling

Researchers used ribonucleic acid (RNA) sequence data to understand the association between inflammatory cytokines and poor outcomes of pediatric Acute Myeloid Leukemia (pAML).

29 Nov 2022

Impact of doubling COVID-19 cases on health parameters

Researchers assessed the impact of the doubling of coronavirus disease 2019 (COVID-19) cases on health parameters.

29 Nov 2022

in vitro News and Research

Low-intensity ultrasound therapies may help rebuild stronger knees

Scientists report the in vitro production of infectious Plasmodium falciparum sporozoites

Understanding why respiratory infections are more common in the winter

Comparison of blood plasma protein expression in mild, moderate, and severe COVID-19 identifies novel disease severity biomarkers

Researchers develop a polyvalent lipid nanoparticle mRNA vaccine against Monkeypox virus

How two structurally different lemon pectins modulate the gut microbiota

Mucosal IgA fused nanobody as a non-invasive, cost-effective prophylaxis and therapeutic option against major SARS-CoV-2 variants

Exploring the effects of dietary fiber on gut microbiome and inflammatory diseases

Collaborative work unravels hidden molecular secrets of age-related diseases

Novel prefusion S antigen designed by the mutation of the SARS-CoV-2 Spike protein’s trimeric structure

The requirement for Fc effector functions to protect against SARS-CoV-2 infection

Impact of COVID-19 on sperm quality

Study provides a framework to guide the development of variant-resistant SARS-CoV-2 vaccines

New urinary biomarkers could help monitor potential abuse of emerging synthetic cannabinoids

Unique scaffolding material shows significant promise in the treatment of spinal cord injury

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Antioxidant and anti-inflammatory properties of Stingless bee-derived propolis against acne

Endogenous system may be responsible for delayed onset of diabetic retinopathy

Pediatric acute myeloid leukemia genetic subtypes with poor outcomes show increased inflammatory cytokine signaling

Impact of doubling COVID-19 cases on health parameters

Driving innovation in drug discovery with in vitro biology solutions eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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