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Study finds how miR-132 acts as ‘handbrake’ on our immune system

Researchers have discovered how a tiny molecule known as miR-132 acts as a "handbrake" on our immune system - helping us fight infection.

5 Mar 2019

New combinational drug therapy may effectively combat pancreatic cancer

Even among cancers, pancreatic cancer is an especially sinister form of disease. The one-year survival rate is extremely low, and treatment progress has lagged behind that of many other malignancies.

5 Mar 2019

Researchers create 3D vascularized proximal tubule model to study renal reabsorption

Every day our kidneys tackle the daunting task of continuously cleaning our blood to prevent waste, salt and excess fluid from building up inside our bodies.

5 Mar 2019

FutureNeuro collaborates with UCB to inform improvements in epilepsy treatment

FutureNeuro, the SFI Research Centre for Chronic and Rare Neurological Diseases, based at RCSI, has partnered with global biopharmaceutical company, UCB, to unlock the power of healthcare data to inform improvements in clinical care of people with epilepsy.

5 Mar 2019

Novel treatment targeting fibroblasts may prevent heart failure after heart attack

Heart attack survivors are at greater risk of developing heart failure, a chronic condition in which more than half of those diagnosed will die within five years.

5 Mar 2019

GARDP and Penta join forces to deal with drug-resistant infections in children

The Global Antibiotic Research & Development Partnership and Penta, the pediatric infectious diseases research network, have joined forces to tackle drug-resistant infections in children.

5 Mar 2019

New ‘microdose’ psychedelic treatment appears to relieve anxiety and depression

Lava lamps, tambourines and, of course, psychedelic drugs were hallmarks of the 1960s. Psychedelic drugs can make people euphoric, though users can also become extremely anxious and agitated. But that's at a high dose.

5 Mar 2019

Peptide derived from fungi prevents growth of tuberculosis bacteria

The discovery of the peptide as a possible future antibiotic was made when the researchers screened different antimicrobial peptides' ability to prevent the growth of the tuberculosis bacteria Mycobacterium tuberculosis.

4 Mar 2019

Research opens door to promising new treatment strategy for deadly brain tumor in children

A study published in Nature Communications found that an inhibitor of an enzyme called ACVR1 slows tumor growth and increases survival in an animal model of diffuse intrinsic pontine glioma - the most deadly brain tumor in children.

4 Mar 2019

Nicotine could affect human embryonic development at the single-cell level

Nicotine induces widespread adverse effects on human embryonic development at the level of individual cells, researchers report February 28th in the journal Stem Cell Reports.

4 Mar 2019

Increased muscle mass could save your life

As far back as Ancient Greece, a sculptured physique has been heralded as the pinnacle of physical perfection. But now, researchers from Japan have found that increased muscle mass doesn't just make you look good, it could literally save your life.

4 Mar 2019

New method could help treat reduced exercise capacity caused by heart failure

A group of Hokkaido University scientists and collaborators have developed a method that could be used to treat heart failure patients whose exercise capacity has been impaired.

4 Mar 2019

Scientists create novel tool to advance search for antibacterial drugs

Indiana University researchers are advancing knowledge about how bacteria build their cell walls that could contribute to the search for new antibacterial drugs. They have created a new tool to observe living cells in real time under a microscope.

4 Mar 2019

Protecting against ‘invisible threat’ that affects cancer care workers

Chemotherapy drugs are lifesaving to cancer patients, but these toxic drugs are hazardous to the health care workers who come into contact with them. Despite the risks, many health care workers do not use recommended personal protective equipment such as gloves or gowns when handling chemotherapy.

2 Mar 2019

Newly developed bioluminescence sensors pave way for drug discovery

Canadian researchers, working in partnership with Brazilian colleagues, have developed 13 bioluminescence sensors for use in testing the effectiveness of new medical drugs in the laboratory.

2 Mar 2019

Wakefulness and novel sleep index may predict success of spontaneous breathing trial

Critically ill patients are more likely to be successfully weaned from a mechanical ventilator, or breathing machine, if they have higher levels of wakefulness and both their right and left brains experience the same depth of sleep, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

1 Mar 2019

New 'electronic nose' is 95% accurate in identifying deadly disease

Fewer dogs in Brazil may be euthanized unnecessarily after researchers showed that a new test is 95% accurate in identifying the deadly disease Leishmaniasis.

1 Mar 2019

Scientists use pulsed infrared light lasers to focus on the action of drugs

Having absolute control of the activity of a molecule in an organism. Deciding when, where and how a drug is activated. These are some of the goals expected to be reached with the so-called photoswitchable molecules, compounds that, in the presence of certain light waves, change their properties.

1 Mar 2019

New multi-year affiliation announced to establish global center for rare diseases

The University of Oxford and University Hospitals in Cleveland, Ohio, today announced a multi-year affiliation to establish a global center for rare diseases.

1 Mar 2019

Translucent wonder material used on stadium roofs helps measure protein particles

Understanding how proteins clump together is essential in modern pharmaceuticals. When these tiny particles aggregate, they can alter the effectiveness of both vaccines and drugs, especially many of the new, popular formulations derived from monoclonal antibodies.

1 Mar 2019