Lungs News and Research

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Passive smoking increases likelihood of lung cancer in children later in life

Children who are exposed to environmental tobacco smoke (passive smoking) are at a higher risk of developing lung cancer as adults, says a paper in this week's BMJ.

30 Jan 2005

Physical traits, genetic test help with early diagnosis of aneurysm syndrome

A research team led by Johns Hopkins doctors has defined the physical traits and genetic basis of a new aortic aneurysm syndrome that is extremely aggressive and can cause death in early childhood. Early diagnosis of the syndrome and rapid surgical repair of the swollen aorta can save lives, the researchers report in the Jan. 30 advance online section of Nature Genetics.

30 Jan 2005

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine will begin in the Washington, DC area in a couple of months after the U.S. Food and Drug Administration conferred investigational new drug status on the vaccine.

27 Jan 2005

Trial of Etanercept for Wegners's disease shows no benefit against the autoimmune condition

A Johns Hopkins-led study designed to evaluate the ability of etanercept to maintain disease remissions in a serious autoimmune disorder has failed to show any benefit. Etanercept, also called Enbrel, is a common treatment for rheumatoid arthritis and other types of joint inflammation.

26 Jan 2005

Why some men develop aggressive prostate cancer that becomes resistant to hormone-withdrawal therapy

Researchers found that certain mutations in a protein called the androgen receptor cause advanced and invasive prostate cancer when put into otherwise healthy mice. The androgen receptor's normal function is to control growth of the prostate gland in response to cues from male hormones called androgens, which have long been thought to stimulate prostate tumors.

26 Jan 2005

Blood clots in the lungs could be prevented with computed tomography (CT) scans of the legs

Researchers found that indirect CT venography (CTV) could identify blood clots in the legs that have the potential to break free, travel to the lung and block an artery--a life-threatening condition known as pulmonary embolism.

25 Jan 2005

High blood pressure risk in African-Americans linked to genetics

National health records have shown that African-Americans are more prone to high blood pressure than Caucasians, but pinning down the roots of that difference has proven elusive. Now, researchers at the Stanford University School of Medicine have narrowed down the search for genes that contribute to this difference in disease risk.

24 Jan 2005

Screening tests find colorectal cancer in its earliest stages when it can be treated more successfully

Colorectal cancer (CRC) is second only to lung cancer as the leading cause of cancer-related death in the United States. In 2004, it’s estimated that CRC caused nearly 57,000 deaths.

18 Jan 2005

Broadening treatment to battle recurrence of endometrial cancer

Mayo Clinic researchers studying endometrial cancer have found that patients at risk for relapse based on identified risk factors had a 46 percent probability of experiencing recurrence within five years despite treatment with state-of-the-art therapy.

18 Jan 2005

Home HIV-AIDS test could be a reality within two years

A portable device similar to a home pregnancy test that can quickly detect the presence of infectious diseases, including HIV-AIDS and measles as well as biological agents such as Ricin and anthrax, is the goal of a new joint research project

17 Jan 2005

Alvesco now available for asthma sufferers in the United Kingdom

Altana AG has announced that Alvesco (Ciclesonide), a novel inhaled corticosteroid (ICS) for the treatment of adults (18+ years) suffering from persistent asthma is now available for the first time in the United Kingdom (UK).

17 Jan 2005

Scientific evidence on passive smoking is inconclusive

Scientific evidence on environmental tobacco smoke (ETS or so-called "passive smoking") is inconclusive and does not justify a total ban on smoking in public places, it was argued at a conference on public smoking in Edinburgh today.

17 Jan 2005

GenoMed files patent application on two genes linked to common cancers

GenoMed announced today that it has filed a patent application on two genes linked to common cancers. These are the first new disease genes the company has filed on since its multiple patent applications about ACE, a "master" disease gene.

17 Jan 2005

Avastin available across Europe within the next few weeks

Roche has announced that the European Commission has approved Avastin (bevacizumab, rhuMAb-VEGF), the new innovative anti-angiogenesis drug, for the treatment of patients with previously untreated metastatic colorectal cancer.

16 Jan 2005

High health care burden of acute chest pain

Chest pain accounts for almost three quarter of a million emergency care visits in England and Wales every year - around double previous estimates - indicates research in Heart.

16 Jan 2005

Tobacco industry involvement in p53 gene research impairs integrity of the scientific process

The strategies used by the tobacco industry to counteract research linking tobacco smoke to cancer-causing mutations in a gene called p53 are detailed in a study published in The Lancet.

13 Jan 2005

Evaluation of BAY 43-9006 (Sorafenib) for pancreatic cancer

Oncologists from USC/Norris Comprehensive Cancer Center are running tests on a new pancreatic cancer drug that targets the cancer from two directions.

13 Jan 2005

Alarming ignorance about cancer in Britain

There is an alarming ignorance about cancer and how to reduce the risk of the disease which is Britain's biggest killer – a special survey reveals today.

13 Jan 2005

Smoking marijuana is associated with increased risk of many of the same symptoms as smoking cigarettes

Smoking marijuana is associated with increased risk of many of the same symptoms as smoking cigarettes--chronic bronchitis, coughing on most days, phlegm production, shortness of breath, and wheezing, according to a Yale study published in the Journal of General Internal Medicine.

13 Jan 2005

First new guidelines in more than a decade for managing asthma during pregnancy

The report reflects new medications that have emerged and updates treatment recommendations for pregnant women with asthma based on a systematic review of data on the safety of asthma medications during pregnancy. An executive summary ("Quick Reference") of the guidelines is published in the January issue of the Journal of Allergy & Clinical Immunology.

12 Jan 2005