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Celgene reports second quarter total revenue of $1.18 billion

Celgene Corporation announced non-GAAP net income of $417 million, or non-GAAP diluted earnings per share of $0.89, for the quarter ended June 30, 2011. Non-GAAP net income for the second quarter of 2010 was $323 million, or non-GAAP diluted earnings per share of $0.69.

28 Jul 2011

New approaches to improve biomarker discovery

An article in the current edition of Chemical & Engineering News, ACS's weekly newsmagazine, describes the trials, tribulations, and triumphs of one of the hottest pursuits in modern biomedical science - the search for "biomarkers" that could greatly improve the diagnosis of disease and efforts to monitor the effectiveness of treatment.

28 Jul 2011

Cigarette smoke exposure alters airway tissue in people with COPD

Cigarette smoke exposure fundamentally alters airway tissue from people with chronic obstructive pulmonary disease (COPD) at the cellular level, laying the groundwork for airway thickening and even precipitating precancerous changes in cell proliferation that may be self-perpetuating long after cigarette smoke exposure ends, according to Australian researchers.

28 Jul 2011

Relative muscle mass inversely linked with insulin resistance and pre-diabetes

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that the greater an individual's total muscle mass, the lower the person's risk of having insulin resistance, the major precursor of type 2 diabetes.

28 Jul 2011

Study examines effect of unhealthy food outlets on adolescent junk food consumption

Got lots of fast food restaurants and other outlets that sell junk food in your neighborhood? Then your teen is more likely to nosh regularly on burgers and fries and wash them down with a soda.

28 Jul 2011

SMRT DNA sequencing technology reveals genetic profile of German E. coli bacteria

An international team of scientists has successfully employed single molecule, real-time DNA sequencing technology from Pacific Biosciences of California, Inc. to provide valuable insights into the pathogenicity and evolutionary origins of the highly virulent bacterium responsible for the German E. coli outbreak.

28 Jul 2011

Arterial spin labeling shows areas of brain activity in chronic low back pain patients

Research from Brigham and Women's Hospital (BWH) uses a new imaging technique, arterial spin labeling, to show the areas of the brain that are activated when patients with low back pain have a worsening of their usual, chronic pain.

28 Jul 2011

Brooklyn drugstores accused of Medicare Part D fraud

With a blue awning with the Russian word for pharmacy written on it and a sign hung in the window declaring "We Accept All Medicare Part D Plans," Monica's looks like a typical mom-and-pop Brooklyn drugstore.

28 Jul 2011

Many factors contribute to high caesarean section rate around the world

A wide range of clinical and non-clinical factors can affect whether women go on to have a vaginal delivery after having a caesarean, according to two major reviews published in the August issue of the Journal of Advanced Nursing.

28 Jul 2011

USAID releases new issue of Frontlines

The June/July issue of USAID's Frontlines focuses on climate change, including an article on how Kenyan farmers are adapting to environmental changes. The issue also includes articles on how the search for an HIV vaccine has boosted African research and on the introduction of the GeneXpert tuberculosis test in Central Asia.

28 Jul 2011

Eli Lilly introduces physician payment registry for public

Eli Lilly and Company today announced the launch of a physician payment registry to help the public better understand how the company works with U.S. physicians and compensates them for their services – and how these collaborations benefit patient care.

28 Jul 2011

World Bank urges China to address NCDs or face economic consequences

In a report released on Tuesday, the World Bank urged China to step up its efforts to fight non-communicable diseases (NCDs), "the main cause of death in the country, warning of rising health expenditure and an economic slowdown if rapid action is not taken," Reuters reports.

28 Jul 2011

U.N. warns 3.5M Kenyans will need food aid by September

The U.N. on Tuesday said approximately 3.5 million Kenyans will need food aid due to drought by September, "while European officials warned such crises would flare up again unless more money was directed at prevention efforts," Reuters reports.

28 Jul 2011

Engineers work to design prosthetic arm that allows amputees to feel what they touch

Engineering researchers at four U.S. universities are embarking on a four-year project to design a prosthetic arm that amputees can control directly with their brains and that will allow them to feel what they touch.

28 Jul 2011

Two large insurers profit by Americans' postponement of care

WellPoint Inc and Aetna Inc , the second and third-biggest U.S. health insurers by market value, are set to report second-quarter earnings on Wednesday that will likely be helped by Americans avoiding doctor visits and delaying medical procedures. The industry has benefited from Americans postponing such care during the weak economy.

28 Jul 2011

Sorin Group's Mitroflow valve with PRT receives CE Mark approval

Sorin Group,, a global medical company and a leader in the treatment of cardiovascular diseases, announced today that it received the CE Mark approval for the Mitroflow Aortic Pericardial Heart Valve with PRT.

28 Jul 2011

Law center presses its health law challenge

"The Thomas Moore Law Center formally asked the Supreme Court Tuesday to reverse an appeals court decision upholding the health care reform law. Marking the first appeal of its kind to reach the nation's highest court, the conservative legal group continues to insist the mandate requiring all Americans to purchase health insurance is unconstitutional".

28 Jul 2011

Mitochondrial genome undergoes random reorganisation during reprogramming

Induced pluripotent stem cells (iPS cells) are truly talented multi-taskers. They can reproduce almost all cell types and thus offer great hope in the fight against diseases like Alzheimer's and Parkinson's. However, it would appear that their use is not entirely without risk: during the reprogramming of body cells into iPS cells, disease-causing mutations can creep into the genetic material.

28 Jul 2011

Pharmaceutical companies' profit protection hurts global AIDS fight

In her latest piece on the New York Times' "Opinionator" blog, author and journalist Tina Rosenberg argues that the terms of Gilead's recent agreement with the Medicines Patent Pool is "confirmation of a dangerous new trend: middle-income countries as a target market for drug makers."

28 Jul 2011

Scientists show how RET gene in breast cancer cells responds to estrogen

Using human breast cancer cells and the protein that causes fireflies to glow, a Johns Hopkins team has shed light on why some breast cancer cells become resistant to the anticancer effects of the drug tamoxifen. The key is a discovery of two genetic "dimmer switches" that apparently control how a breast cancer gene responds to the female hormone estrogen.

28 Jul 2011