Inflammation News and Research

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Ipilimumab and bevacizumab drugs effective in treating metatastic melanoma

A duo of drugs, each targeting a prime survival strategy of tumors, can be safely administered and are potentially more effective than either drug alone for advanced, inoperable melanomas, according to a phase 1 clinical trial led by Dana-Farber Cancer Institute investigators.

4 Jun 2011

Majority of patients with ulcerative colitis eager to undergo fecal microbiota transplantation

The first study of the social and ethical issues associated with a provocative approach to treatment for ulcerative colitis has found that the majority of potential patients are eager for what is now called "fecal microbiota transplantation" to become available, although many have concerns about donor selection, screening, and methods of delivery.

3 Jun 2011

Fatty diet during pregnancy linked to increased risk of placental inflammation, stillbirth

Eating a high-fat diet during pregnancy increases the chance of stillbirth, according to new research at Oregon Health & Science University. The new data show eating a typical American diet, which is high in fat, decreases blood flow from the mother to the placenta, the temporary organ that nourishes the unborn fetus.

3 Jun 2011

Green tea consumption increases number of 'regulatory T cells', prevents autoimmune disease

One of the beneficial compounds found in green tea has a powerful ability to increase the number of "regulatory T cells" that play a key role in immune function and suppression of autoimmune disease, according to new research in the Linus Pauling Institute at Oregon State University.

3 Jun 2011

Elevated CRP levels predict poor prognosis of breast cancer

Levels of C-reactive protein (CRP) are increased in response to acute inflammation, infection and tissue damage. There are also reports that CRP levels are elevated because of cancer.

3 Jun 2011

Researchers explore relationship between emotions and poor prognosis in heart disease

Intense distress and fear of dying, which many people experience when suffering the symptoms of a heart attack, are not only fairly common emotional responses but are also linked to biological changes that occur during the event, according to new research published online today in the European Heart Journal.

2 Jun 2011

PCF funds 14 new Creativity Awards for advanced prostate cancer research

The Prostate Cancer Foundation today announced that it has funded 14 new Creativity Awards for advanced prostate cancer research. These two-year awards are designed to support innovative research ideas that have the potential to achieve breakthroughs for improved prostate cancer diagnosis and treatment.

2 Jun 2011

Plasma resuscitation restores damage to endothelial glycocalyx after hemorrhagic shock

Using plasma rather than standard resuscitation fluids seems to improve survival in trauma patients with massive blood loss. Now a new study in animals suggests that this benefit may result from plasma's ability to restore the "endothelial glycocalyx," a special layer lining the blood vessels, reports the June issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

1 Jun 2011

Appendix and tonsil surgeries before age 20 can increase risk of premature heart attack

The surgical removal of the appendix and tonsils before the age of 20 was associated with an increased risk of premature heart attack in a large population study performed in Sweden. Tonsillectomy increased the risk by 44% (hazard ratio 1.44) and appendectomy by 33% (HR 1.33).

1 Jun 2011

Natural killer cells promote induction of dry eye disease: New discovery

If you are one of the millions of people around the world who struggle with dry eye disease, good news is on the way. A new research discovery published in the Journal of Leukocyte Biology offers hope for new drugs that treat the cellular cause of the disease rather than its symptoms.

1 Jun 2011

Ampio commences new anti-inflammatory agent Phase 1B trial in osteoarthritis

Ampio Pharmaceuticals, Inc. announced today that it received ethics board approval for a Phase 1B clinical trial in Australia of its biologic anti-inflammatory agent, Ampion.

1 Jun 2011

Scientists develop carbohydrate-based vaccine against C. difficile infection

There is now a promising vaccine candidate for combating the pathogen which causes one of the most common and dangerous hospital infections. An international team of scientists from the Max Planck Institute of Colloids and Interfaces in Potsdam has developed a vaccine based on a carbohydrate against the Clostridium difficile bacterium, which is known to cause serious gastrointestinal diseases mainly in hospitals.

31 May 2011

Study: E-waste linked to adverse effects on human health

In addition to its damaging effect on the environment and its illegal smuggling into developing countries, researchers have now linked e-waste to adverse effects on human health, such as inflammation and oxidative stress - precursors to cardiovascular disease, DNA damage and possibly cancer.

31 May 2011

Positive data from Augurex's RA biomarker blood test, novel drug target presented at EULAR conference

Augurex Life Sciences Corp. today reported that in London at the European League Against Rheumatism Conference, leading arthritis researchers presented important data on Augurex's rheumatoid arthritis biomarker blood test and novel drug target.

30 May 2011

Oceana Therapeutics receives FDA approval for Solesta injectable gel to treat fecal incontinence

The U.S. Food and Drug Administration today approved a sterile, injectable gel to treat fecal incontinence in patients for whom other therapies such as diet change, fiber therapy or anti-motility medications failed.

30 May 2011

Possible defense for community-acquired pneumonia among the elderly

Community-acquired pneumonia is the leading cause of infectious death among the elderly. Newly published research from The University of Texas Health Science Center San Antonio suggests why older people are vulnerable and offers a possible defense.

27 May 2011

Study: Cardiovascular disease may be under treated in rheumatoid arthritis patients

Results of a study, involving 98,454 patients demonstrated that at 30 days following their first heart attack, RA patients were approximately 20% less likely to be prescribed standard MI treatments, such as statins and betablockers, compared to healthy patients.

27 May 2011

Lactate shuttle also exists in human tumors

Researchers at the Kimmel Cancer Center at Jefferson have shed new light on the longstanding conundrum about what makes a tumor grow-and how to make it stop. Interestingly, cancer cells accelerate the aging of nearby connective tissue cells to cause inflammation, which ultimately provides "fuel" for the tumor to grow and even metastasize.

27 May 2011

Two new hepatitis C drugs effectively improve cure rates of African Americans

Two new drugs just approved by the Food and Drug Administration to treat hepatitis C genotype 1 significantly improved the cure rates of patients. One of the drugs was extremely effective in treating African Americans.

27 May 2011

4SC to present pre-clinical data on vidofludimus in systemic lupus erythematosus at EULAR 2011

4SC AG, a discovery and development company of targeted small molecule drugs for autoimmune and cancer diseases, will present pre-clinical data on vidofludimus - its lead small-molecule drug candidate against autoimmune diseases - in systemic lupus erythematosus at EULAR 2011, Europe's largest scientific conference on rheumatic diseases, in London, UK, from May 25-28, 2011.

27 May 2011

Inflammation News and Research

Ipilimumab and bevacizumab drugs effective in treating metatastic melanoma

Majority of patients with ulcerative colitis eager to undergo fecal microbiota transplantation

Fatty diet during pregnancy linked to increased risk of placental inflammation, stillbirth

Green tea consumption increases number of 'regulatory T cells', prevents autoimmune disease

Elevated CRP levels predict poor prognosis of breast cancer

Researchers explore relationship between emotions and poor prognosis in heart disease

PCF funds 14 new Creativity Awards for advanced prostate cancer research

Plasma resuscitation restores damage to endothelial glycocalyx after hemorrhagic shock

Appendix and tonsil surgeries before age 20 can increase risk of premature heart attack

Natural killer cells promote induction of dry eye disease: New discovery

Ampio commences new anti-inflammatory agent Phase 1B trial in osteoarthritis

Scientists develop carbohydrate-based vaccine against C. difficile infection

Study: E-waste linked to adverse effects on human health

Positive data from Augurex's RA biomarker blood test, novel drug target presented at EULAR conference

Oceana Therapeutics receives FDA approval for Solesta injectable gel to treat fecal incontinence

Possible defense for community-acquired pneumonia among the elderly

Study: Cardiovascular disease may be under treated in rheumatoid arthritis patients

Lactate shuttle also exists in human tumors

Two new hepatitis C drugs effectively improve cure rates of African Americans

4SC to present pre-clinical data on vidofludimus in systemic lupus erythematosus at EULAR 2011

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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