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Vanderbilt researchers achieve milestone in Alzheimer's drug development

Researchers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the Vanderbilt University School of Medicine Basic Sciences, have detailed the successful drug discovery of a phase I single ascending dose clinical trial of VU319, a drug for memory loss in people with Alzheimer's disease and schizophrenia.

19 Dec 2024

Can probiotics restore antibiotic-perturbed microbiota?

Probiotics can reduce antibiotic-associated diarrhea but don't fully restore gut microbiota. Further studies are essential to evaluate their long-term effects.

19 Dec 2024

The role of phytochemicals in combating metabolic diseases

This editorial reviews the impact of phytochemicals on metabolic diseases, emphasizing their potential in reducing inflammation and improving health outcomes.

19 Dec 2024

Australian researchers discover potential lifeline for premature babies

Australian researchers have discovered a potential new lifeline for the tiniest and most vulnerable newborns. Scientists at Monash Children's Hospital have successfully collected and reinfused umbilical cord blood cells in extremely premature babies, offering a glimmer of hope for preventing brain injuries.

18 Dec 2024

Researchers investigate oxygen's effect on overactive cells in type 2 diabetes

Researchers from the University of Missouri are studying potential therapies to target specific cells linked to the development of cardiovascular and metabolic disorders like high blood pressure and type 2 diabetes.

18 Dec 2024

New app offers relief for parents mourning the loss of a child

A new study shows that an app can help parents who are mourning the loss of a child. Parents who used the app for three months reported reduced symptoms of prolonged grief and post-traumatic stress, and also had fewer negative thoughts.

18 Dec 2024

Genetic testing improves care for pediatric neurodevelopmental disorders

Adding genetic testing to the evaluation of pediatric patients with neurodevelopmental disorders (NDD) resulted in more individualized care, including changes in medication, referrals to clinical trials or specialists, and surveillance for potential medical issues, according to a new UCLA Health study.

18 Dec 2024

Clinical trial to evaluate minimally invasive procedure for women with pelvic venous disease

A multicenter randomized, controlled clinical trial aims to test whether a minimally invasive treatment can relieve chronic pelvic pain and improve the quality of life for women with pelvic venous disease (PeVD).

18 Dec 2024

New molecular imaging agent can accurately identify crucial cancer biomarker

A new molecular imaging agent can accurately identify a crucial biomarker found among many different types of cancer.

18 Dec 2024

Study demonstrates safety of neural stem cell transplant for treating chronic spinal cord injury

A Phase I clinical trial led by researchers at University of California San Diego School of Medicine has demonstrated the long-term safety and feasibility of neural stem cell transplantation for treating chronic spinal cord injuries.

18 Dec 2024

CBD can be used safely in women with advanced breast cancer and clinical anxiety

This Phase II trial explores CBD for anxiety in breast cancer patients, indicating safety and potential anxiolytic effects despite no primary outcome success.

18 Dec 2024

Automated system enhances stroke rehabilitation using robots

The increasing number of strokes and subsequent rehabilitation has highlighted the growing need for effective care strategies.

18 Dec 2024

Huntsman Cancer Institute joins innovative clinical trials program for blood cancers

Huntsman Cancer Institute at the University of Utah (the U) has joined other institutions in an innovative clinical trials program designed to match patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) with a clinical trial specifically designed for the genetic signature of their disease.

17 Dec 2024

Chemical compound lights up treatment-resistant cancers on imaging scans

Researchers have used a chemical compound to light up treatment-resistant cancers on imaging scans, in a breakthrough that could help medical professionals better target and treat cancer.

17 Dec 2024

New radiation therapy approach improves survival for older glioblastoma patients

Mayo Clinic announces the results of an innovative treatment approach that may offer improvement in overall survival in older patients with newly diagnosed glioblastoma while maintaining quality of life.

17 Dec 2024

Pioneering study shows promising results for cognitive treatment in Down syndrome

The ICOD (Improving Condition in Down syndrome) project, a pioneering study in addressing the cognitive difficulties associated with Down syndrome, has demonstrated the safety of treatment with the molecule AEF0217, developed by the French biotech Aelis Farma, as well as its effectiveness in improving cognitive function in these people.

17 Dec 2024

Federal funding boosts effort to make eye transplants a reality

A federal funding agency that supports high-impact research capable of driving biomedical and health breakthroughs has awarded up to $47 million for a project aimed at moving eye transplants to restore vision closer to reality.

16 Dec 2024

WashU Medicine receives $10.8 million grant to advance blood cancer research

Continuing its role as a leader in leukemia research, Washington University School of Medicine in St. Louis has been awarded a five-year, $10.8 million grant to further its exceptional programs in leukemia and other blood cancers.

16 Dec 2024

Researchers investigate CBD's effect on scan-related anxiety in breast cancer patients

The findings showed that CBD did not significantly change scan-related anxiety when compared to a placebo, but researchers did find that CBD was safe and resulted in significantly lower overall anxiety levels.

16 Dec 2024

Breaking the vape habit: Challenges faced by young adult users

A randomized clinical trial explored the characteristics of young adult exclusive e-cigarette users seeking treatment, revealing high dependence levels, significant behavioral health concerns, and common usage of nicotine replacement therapies. Findings underscore the need for tailored cessation strategies targeting young adults.

15 Dec 2024