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New City of Hope CAR T cell trial focuses on HER2-positive breast cancer patients with brain metastases

Women with HER2-positive breast cancer that has spread to the brain need more treatment options, and City of Hope and Mustang Bio Inc. are meeting that challenge.

30 Oct 2018

Gene that makes some people susceptible to middle ear infections identified

Researchers at the University of Colorado Anschutz Medical Campus have found multiple genetic variants within the FUT2 gene that makes some people especially susceptible to middle ear infections.

25 Oct 2018

Head and neck cancer survivors more likely to commit suicide

Despite improved survival rates among cancer patients, the risk of death by suicide remains high, especially among those treated for head and neck cancers.

25 Oct 2018

Biological factors not responsible for racial differences in colorectal cancer incidence

A systematic review and meta-analysis from the Regenstrief Institute and Indiana University School of Medicine has found that, in spite of the higher incidence and death rate of colorectal cancer in blacks, no difference exists in the overall prevalence of advanced, precancerous polyps between average-risk blacks and whites who underwent a screening colonoscopy.

24 Oct 2018

Tall people more likely to get cancers, finds study

A new study suggests that tall people are more likely to get cancers because they have more number of cells that can undergo dangerous mutations.

24 Oct 2018

CRC incidence rates among young adults across Europe increasing by 6% every year

Data from 20 European national cancer registries was used to analyze trends in incidence rates of young adults with CRC across Europe over the last 25 years.

23 Oct 2018

New type of molecule shows early promise against treatment-resistant prostate cancer

A new type of molecule blocks the action of genes that drive the growth of therapy-resistant prostate cancer, a new study finds.

23 Oct 2018

SLU researcher seeks to find solutions for 'chemo brain' symptoms and side effects of opioids

With a pair of RO1 grants from the National Institutes of Health, pain researcher Daniela Salvemini, Ph.D., will embark on two new research projects, studying chemotherapy-induced cognitive impairment, or "chemo brain," symptoms and unwanted side effects of opioids.

23 Oct 2018

Immunotherapy achieves major pathological response in early-stage mismatch repair deficient colon cancer

Pre-operative treatment with a combination of the immune checkpoint inhibitors nivolumab and ipilimumab achieves major pathological responses in 100% of early-stage colon cancers with mismatch repair deficiencies, according to results reported at ESMO 2018 from the first exploratory phase II trial to investigate this approach.

22 Oct 2018

At-home biofeedback therapy effective in relieving difficult-to-treat constipation

Biofeedback therapy used at home is about 70 percent effective at helping patients learn how to coordinate and relax bowel muscles and relieve one of the most difficult-to-treat types of constipation, investigators report.

22 Oct 2018

Case Comprehensive Cancer Center wins NIH grant to study health disparities

The Case Comprehensive Cancer Center has received a three-year, $3,194,947 grant from the National Cancer Institute to investigate colorectal and breast cancer health disparities.

19 Oct 2018

Study shows close link between cytokine interleukin-1ß and obesity-promoted colon cancer

A new study describes the mechanistic relationship between the cytokine interleukin-1β, (IL-1β) and obesity, showing that when IL-1β levels are increased in obesity, IL-1 receptor signaling activates multiple pathways leading to colon cancer.

18 Oct 2018

Patients once thought incurable can benefit from high-dose radiation therapy

In the first randomized, phase II clinical trial of its kind, researchers have shown that an aggressive form of high-precision radiation therapy can greatly increase how long oligometastatic patients live and doubles how long they live without cancer.

17 Oct 2018

New blood test for pediatric brain tumor patients offers safer approach than surgical biopsies

A new blood test for children with brain tumors offers a safer approach than surgical biopsies and may allow doctors to measure the effectiveness of treatment even before changes are identified on scans, according to research led by UCSF Benioff Children’s Hospitals and Children’s National Health System.

16 Oct 2018

Study pinpoints new marker that can predict Crohn’s disease subtype

Crohn's disease, a chronic inflammatory condition of the intestinal tract, has emerged as a global disease, with rates steadily increasing over the last 50 years.

16 Oct 2018

Modeling Non-Numerical Data in Systems Biology

An interview with Dr. Eshan Mitra, discussing the importance of computer models in biology and the development of a more accurate model of the RAF phosphorylation pathway.

15 Oct 2018

Study unravels how cancer stem cells use normal genes in abnormal ways

CDK1 is a "normal" protein - its presence drives cells through the cycle of replication. And MHC Class I molecules are "normal" as well - they present bits of proteins on the surfaces of cells for examination by the immune system.

15 Oct 2018

Obesity associated with higher risk of early-onset colorectal cancer

Women who are overweight or obese have up to twice the risk of developing colorectal cancer before age 50 as women who have what is considered a normal body mass index (BMI), according to new research led by Washington University School of Medicine in St. Louis.

12 Oct 2018

Inflammatory proteins in the colon increase in parallel with increasing weight, study shows

Studies in mice have demonstrated that obesity-induced inflammation contributes to the risk of colorectal cancer, but evidence in humans has been scarce.

11 Oct 2018

International audit of colorectal surgeries provides highly realistic reflection of current practices

The European Society of Coloproctology has undertaken a major international audit of colorectal operations to understand which are most widely used techniques across the world, which appear to be associated with the best outcomes and where further research needs to be undertaken.

10 Oct 2018

Colon News and Research

New City of Hope CAR T cell trial focuses on HER2-positive breast cancer patients with brain metastases

Gene that makes some people susceptible to middle ear infections identified

Head and neck cancer survivors more likely to commit suicide

Biological factors not responsible for racial differences in colorectal cancer incidence

Tall people more likely to get cancers, finds study

CRC incidence rates among young adults across Europe increasing by 6% every year

New type of molecule shows early promise against treatment-resistant prostate cancer

SLU researcher seeks to find solutions for 'chemo brain' symptoms and side effects of opioids

Immunotherapy achieves major pathological response in early-stage mismatch repair deficient colon cancer

At-home biofeedback therapy effective in relieving difficult-to-treat constipation

Case Comprehensive Cancer Center wins NIH grant to study health disparities

Study shows close link between cytokine interleukin-1ß and obesity-promoted colon cancer

Patients once thought incurable can benefit from high-dose radiation therapy

New blood test for pediatric brain tumor patients offers safer approach than surgical biopsies

Study pinpoints new marker that can predict Crohn’s disease subtype

Modeling Non-Numerical Data in Systems Biology

Study unravels how cancer stem cells use normal genes in abnormal ways

Obesity associated with higher risk of early-onset colorectal cancer

Inflammatory proteins in the colon increase in parallel with increasing weight, study shows

International audit of colorectal surgeries provides highly realistic reflection of current practices

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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