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Risk factors for rare COVID-19 complications in children (MIS-C)

While the earlier waves of COVID-19 relatively spared children, some of the affected children have developed a systemic inflammatory condition, with occasionally fatal outcomes. Called multisystem inflammatory syndrome in children (MIS-C), its pathogenesis and risk factors are the subject of a new study on the medRxiv* preprint server.

21 May 2021

Facets of SARS-CoV-2 infection and animal models

A new study in the journal Frontiers in Cell and Developmental Biology discusses the ribonucleic acid (RNA) genome of the virus, and the mechanisms by which it establishes infection within the host cell. The researchers also summarize the development of animal models of COVID-19, which will both help understand the clinical features of the illness, and indicate new approaches for the treatment of the infection.

21 May 2021

Are COVID-19-related complications in children explained by abnormal immune responses?

A common theme in reports on COVID-19 around the world has been the large number of children who have not been infected or shown signs of disease. However, though the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes less acute infection in this age group, it is associated with a severe immune-mediated multisystemic illness called multisystem inflammatory syndrome in children (MIS-C).

20 May 2021

Early treatment may prevent clotting in COVID-19 vaccine-related thrombocytopenia

Now, a new report in the Journal of Thrombosis and Hemostasis reveals that timely diagnosis and treatment of this condition may prevent further morbidity and mortality, and enable the vaccine to be used widely with confidence.

20 May 2021

Four months of multi-drug therapy for tuberculosis is as effective as standard regimen

Four months of multi-drug therapy that included rifapentine and moxifloxacin treated active tuberculosis (TB) as effectively as the standard six-month regimen in a multinational study, cutting treatment time by a third.

20 May 2021

Study confirms that human endocrine system is strongly involved in SARS-Cov-2 infection

The endocrine system is strongly involved in SARS-Cov-2 infection - so much so that evidence of an "endocrine phenotype" of COVID-19 has emerged, according to a statement by the European Society of Endocrinology (ESE) published in the journal Endocrine in April 2021.

20 May 2021

Animal and insect invasions could shed light on COVID-19 transmission

Invasions by alien insect and animal species have much in common with outbreaks of infectious diseases and could tell us a great deal about how pandemics spread, according to a research paper published today.

19 May 2021

A possible human-to-canine transmission of SARS-CoV-2

Now, researchers at the U.S. Centers for Disease Control and Prevention (CDC) identified a case of human to animal transmission when SARS-CoV-2 was detected in a healthy poodle dog living with four family members who had COVID-19.

18 May 2021

COVID-19 mRNA vaccines safe and effective for pregnant and breastfeeding women

The current coronavirus disease 2019 (COVID-19) pandemic has brought untold devastation in its wake, with its rapid and asymptomatic spread to hundreds of millions of people the world over. Vaccines have been hailed as the way out of this situation, and a dozen or so are being rolled out in many different countries.

18 May 2021

Survey: 40% of people with liver disease have been worried about mental health impact of the pandemic

A survey by the British Liver Trust in March 2021 has revealed that 40% of people with liver disease have been worried about their mental health during the pandemic.

17 May 2021

Investigational drug reduced triglycerides in patients with severe hypertriglyceridemia, acute pancreatitis

The investigational drug evinacumab reduced triglycerides in patients with severe hypertriglyceridemia (sHTG) and a history of hospitalizations for acute pancreatitis in a phase 2 global study led by Mount Sinai.

17 May 2021

High-density microarray patch could help vaccinate for dengue in a single click

A dengue virus vaccine candidate has passed an important milestone, with promising results in animal model testing providing hope to the 390 million people infected every year.

13 May 2021

Huge healthcare burden of post-COVID-19 symptoms likely, suggests new study

How well do patients who had COVID-19 recover after the virus is cleared from their systems? A new preprint reports on symptom profiles over the first nine months of the illness.

13 May 2021

Scientists unveil new Ebola virus vaccine design

Scientists at Scripps Research have unveiled a new Ebola virus vaccine design, which they say has several advantages over standard vaccine approaches for Ebola and related viruses that continue to threaten global health.

13 May 2021

Investment in primary prevention can reduce rheumatic heart disease in the African Union

Rheumatic heart disease (RHD) remains a major cause of cardiovascular disease in Africa, even as acute rheumatic fever and RHD have become rare in high-income countries.

12 May 2021

Covid-19 patients show reduced gray matter volume in the brain

Covid-19 patients who receive oxygen therapy or experience fever show reduced gray matter volume in the frontal-temporal network of the brain, according to a new study led by researchers at Georgia State University and the Georgia Institute of Technology.

12 May 2021

Case study describes consequences of undetected SARS-CoV-2 infection during mRNA vaccination

Now, a new report describes a case of a coincidental mRNA vaccination and SARS-CoV-2 infection in a 31-year-old doctor, addressing the theoretical considerations for potential risks and further required actions in case more cases appear in the future.

11 May 2021

Severe COVID-19 linked to genetic clotting predisposition

Thus, the need to stratify the risk of severe or critical disease in patients presenting with SARS-CoV-2 infection remains a crying necessity. A new preprint research paper posted to the medRxiv server discusses the relationship between severe disease and pre-existing susceptibility to clots and other diseases of the cardiovascular system.

11 May 2021

FDA expands emergency use authorization for Pfizer-BioNTech COVID-19 Vaccine

Today, the U.S. Food and Drug Administration expanded the emergency use authorization (EUA) for the Pfizer-BioNTech COVID-19 Vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to include adolescents 12 through 15 years of age.

10 May 2021

Natural products a rich source for novel antiviral compounds

In a recent review in the journal Viruses, researchers look at natural products that can be identified as potential alternative antiviral agents. The reviewers discussed the antiviral activities of several natural products towards DNA and RNA viruses with an analytical approach. The researchers detailed the cellular/viral targets of the active molecules and their impact on the infection and viral replication cycle.

10 May 2021

Fever News and Research

Risk factors for rare COVID-19 complications in children (MIS-C)

Facets of SARS-CoV-2 infection and animal models

Are COVID-19-related complications in children explained by abnormal immune responses?

Early treatment may prevent clotting in COVID-19 vaccine-related thrombocytopenia

Four months of multi-drug therapy for tuberculosis is as effective as standard regimen

Study confirms that human endocrine system is strongly involved in SARS-Cov-2 infection

Animal and insect invasions could shed light on COVID-19 transmission

A possible human-to-canine transmission of SARS-CoV-2

COVID-19 mRNA vaccines safe and effective for pregnant and breastfeeding women

Survey: 40% of people with liver disease have been worried about mental health impact of the pandemic

Investigational drug reduced triglycerides in patients with severe hypertriglyceridemia, acute pancreatitis

High-density microarray patch could help vaccinate for dengue in a single click

Huge healthcare burden of post-COVID-19 symptoms likely, suggests new study

Scientists unveil new Ebola virus vaccine design

Investment in primary prevention can reduce rheumatic heart disease in the African Union

Covid-19 patients show reduced gray matter volume in the brain

Case study describes consequences of undetected SARS-CoV-2 infection during mRNA vaccination

Severe COVID-19 linked to genetic clotting predisposition

FDA expands emergency use authorization for Pfizer-BioNTech COVID-19 Vaccine

Natural products a rich source for novel antiviral compounds

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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