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Scripps Research professor wins $3.2 million grant to unravel the mysteries of type 1 diabetes

Luc Teyton, professor in the Department of Immunology and Microbiology at Scripps Research, has received a five-year, $3.2 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to help answer how type 1 diabetes manifests and develop potential therapeutics to reverse or prevent the disease.

29 Oct 2025

Systematic analysis reveals psilocybin's impact on obsessive-compulsive behaviors

A systematic review published today in Psychedelics by Mr. James Gattuso and colleagues at the Florey Institute of Neuroscience and Mental Health synthesizes clinical and preclinical evidence on psilocybin's effects on obsessive-compulsive behaviors, revealing consistent therapeutic potential across human patients and validated animal models.

29 Oct 2025

Retaining gonad function could be a potent strategy to fight late-life frailty

Frailty threatens older individuals because it increases their vulnerability to detrimental health outcomes, such as falling, longer hospitalization, or even shortened life expectancy.

29 Oct 2025

Unlocking memory: The role of epigenetics in memory expression

Our experiences leave traces in the brain, stored in small groups of cells called "engrams". Engrams are thought to hold the information of a memory and are reactivated when we remember, which makes them very interesting to research on memory and age- or trauma-related memory loss.

29 Oct 2025

MIT study reveals what happens inside the brain during sleep deprivation

Nearly everyone has experienced it: After a night of poor sleep, you don't feel as alert as you should. Your brain might seem foggy, and your mind drifts off when you should be paying attention.

29 Oct 2025

Enhancing ALS diagnosis with dual blood biomarkers

Despite modern imaging and genetic testing, diagnosing amyotrophic lateral sclerosis (ALS) remains challenging, particularly when distinguishing it from clinically similar neurodegenerative disorders.

29 Oct 2025

Unlocking the secrets of NMDA receptors for better brain health

As information zings from cell to cell inside the brain, bursts of electricity spur its transmission. At Cold Spring Harbor Laboratory (CSHL), scientists have turned their attention to the tiny pores that let charged ions enter a cell-and the molecular gatekeepers that help control them.

29 Oct 2025

Novel 3D chromosome mapping method can reliably reveal hidden structural variants

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new discoveries.

29 Oct 2025

Broad-spectrum antivenom could revolutionize treatment of venomous snakebites in Africa

DTU researchers are behind a potentially groundbreaking antivenom that could revolutionize the treatment of venomous snakebites in Africa.

29 Oct 2025

Two analgesic drugs may one day be repurposed as anti-tumor therapies

Peripheral afferent neurons - nerves that send signals from all areas of the body to the central nervous system (brain and spinal cord) - are known to infiltrate and grow within malignant bone tumors called osteosarcomas, often accompanied by severe pain.

29 Oct 2025

Some acute and chronic viral infections linked to increased risk of cardiovascular disease

In the weeks following a bout of influenza or COVID, the risk of heart attack or stroke may rise dramatically, and chronic infections such as HIV may increase the long-term risk of serious cardiovascular disease events, according to new, independent research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

29 Oct 2025

Unraveling the secrets of neuronal mechanotransduction

How do embryos develop? Why does the cortex of the mammalian brain fold? How do we feel touch at our fingertips? These and other fundamental biological questions remain unsolved.

29 Oct 2025

Heart ‘blueprint’ offers insights into fetal development and congenital defects

New research in Sweden has produced a "blueprint" revealing how the human heart is built during prenatal development.

29 Oct 2025

AI-powered LifeClock forecasts diseases years before symptoms appear

Researchers have developed LifeClock, an AI-driven biological clock trained on over 24 million electronic health records to estimate biological age across the human lifespan. The model accurately predicts disease risk years in advance, revealing distinct developmental and aging processes.

28 Oct 2025

Study highlights non-inferiority of super-high-pressure non-compliant balloons in coronary interventions

New study findings show that utilizing super-high-pressure non-compliant balloons (NCB) is non-inferior to intravascular lithotripsy (IVL) balloon catheters for lesion preparation and stent expansion in severely calcified lesions during percutaneous coronary intervention (PCI).

28 Oct 2025

Mount Sinai receives $4.5 million grant to investigate neural mechanisms underlying bipolar disorder

The Icahn School of Medicine at Mount Sinai is pleased to announce it has received a three-year, $4.5 million grant from BD2: Breakthrough Discoveries for thriving with Bipolar Disorder to investigate the neural mechanisms underlying bipolar disorder and pioneer novel neuromodulation-based treatment strategies.

28 Oct 2025

COVID-19 pandemic linked to diminishing public trust in childhood vaccines

An international study led by the Azrieli Faculty of Medicine in the Galilee at Bar-Ilan University reveals that the COVID-19 pandemic has contributed to a diminishing public trust in childhood vaccines, resulting in declining vaccination rates and a resurgence of preventable, life-threatening diseases such as measles.

28 Oct 2025

Sirolimus-eluting balloon strategy matches drug-eluting stents in large international PCI trial

New study results from a large international all-comer population of percutaneous coronary intervention (PCI) candidates found that utilizing a strategy of sirolimus-eluting balloons with bailout stenting only if necessary was noninferior to routine drug-eluting stent (DES) implantation as part of the treatment for de novo coronary artery disease.

27 Oct 2025

Senegal initiates comprehensive response to Rift Valley fever outbreak

Senegal has launched a nationwide, multisectoral response to tackle a growing outbreak of Rift Valley fever (RVF), warning affected communities against risky self-medication.

27 Oct 2025

Study finds evidence for repurposing thiostrepton as an anti-rhabdomyosarcoma drug

Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.

27 Oct 2025

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Laboratory News and Research

Scripps Research professor wins $3.2 million grant to unravel the mysteries of type 1 diabetes

Systematic analysis reveals psilocybin's impact on obsessive-compulsive behaviors

Retaining gonad function could be a potent strategy to fight late-life frailty

Unlocking memory: The role of epigenetics in memory expression

MIT study reveals what happens inside the brain during sleep deprivation

Enhancing ALS diagnosis with dual blood biomarkers

Unlocking the secrets of NMDA receptors for better brain health

Novel 3D chromosome mapping method can reliably reveal hidden structural variants

Broad-spectrum antivenom could revolutionize treatment of venomous snakebites in Africa

Two analgesic drugs may one day be repurposed as anti-tumor therapies

Some acute and chronic viral infections linked to increased risk of cardiovascular disease

Unraveling the secrets of neuronal mechanotransduction

Heart ‘blueprint’ offers insights into fetal development and congenital defects

AI-powered LifeClock forecasts diseases years before symptoms appear

Study highlights non-inferiority of super-high-pressure non-compliant balloons in coronary interventions

Mount Sinai receives $4.5 million grant to investigate neural mechanisms underlying bipolar disorder

COVID-19 pandemic linked to diminishing public trust in childhood vaccines

Sirolimus-eluting balloon strategy matches drug-eluting stents in large international PCI trial

Senegal initiates comprehensive response to Rift Valley fever outbreak

Study finds evidence for repurposing thiostrepton as an anti-rhabdomyosarcoma drug

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