Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Cell fusion could be a potential therapeutic strategy to treat retinal damage

Fusing human retinal cells with adult stem cells could be a potential therapeutic strategy to treat retinal damage and visual impairment, according to the findings of a new study published in the journal eBioMedicine.

15 Mar 2022

Mason scientists receive DOD funding for breast cancer prevention and treatment research

George Mason University College of Science announced a $1.57 million dollar grant from the Department of Defense to fund a transformative approach for breast cancer treatment developed by scientists in Mason's Center for Drug Discovery for Rare Diseases.

15 Mar 2022

Using mRNA to introduce gene editor into human muscle stem cells

Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.

14 Mar 2022

Study raises hopes for effective treatment of infant B acute lymphoblastic leukemia

New research has begun to unravel the mystery of why a particular form of leukemia in infants has defied efforts to improve outcomes, despite significant improvements in treating older children.

14 Mar 2022

Single protein elicits multilineage reprogramming of astrocytes in adult mouse brains

A single protein can reverse the developmental clock on adult brain cells called astrocytes, morphing them into stem-like cells that produce neurons and other cell types, UT Southwestern researchers report in a PNAS study.

9 Mar 2022

Study identifies new immune checkpoint that may be exploited for cancer treatment

A collaborative study led by the Monash Biomedicine Discovery Institute has discovered a new immune checkpoint that may be exploited for cancer therapy.

8 Mar 2022

How have human organoids been used in research to study SARS-CoV-2?

In a recent review published in the journal Organoids, scientists have presented an overview on the use of human stem cell-derived organoids in understanding functionality and cellular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a deadly beta-coronavirus responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic.

7 Mar 2022

Some blood cells remain in tissues for years, research finds

Human immune cells not only circulate in the blood, but can also occupy certain tissues and sometimes remain there for years.

7 Mar 2022

Slowing down the DNA replication speed increases cell reprogramming efficiency

Adult cells in our body can only give rise to the same cell type. For example, a skin cell cannot give rise to a muscle cell but to skin cells only.

7 Mar 2022

World Trade Center responders have increased levels of mutations that escalate blood cancer risk

Scientists from Vanderbilt-Ingram Cancer Center (VICC) collaborated with researchers from New York to determine that 9/11 first responders to the World Trade Center have increased levels of mutations that escalate their risk for blood cancers or cardiovascular disease, according to a study published March 7 in Nature Medicine.

7 Mar 2022

Study uncovers new clues about the cellular processes that can lead to androgen deficiency

A laboratory study at the Miller School of Medicine's Desai Sethi Urology Institute has uncovered new clues about the cellular processes that can lead to deficiencies of androgens (male hormones) such as testosterone.

4 Mar 2022

Researchers design a peptide hydrogel for cell spheroids production

This study is led by Prof. Zhimou Yang and Prof. Quan Chen (College of Life Sciences in Nankai University), and Prof. Jianfeng Liu (Institute of Radiation Medicine, Chinese Academy of Medical Sciences). Prof. Zhimou Yang, who is working in the research field of peptide self-assembly biomaterials for more than 15 years, designed the peptide hydrogel for cell spheroids production.

4 Mar 2022

Researchers take pioneering efforts to optimize the functionality of pancreatic cells produced from stem cells

Helsingin yliopisto (University of Helsinki) Insulin is a vital hormone produced by pancreatic beta cells. Type 1 diabetes is caused by the destruction of these cells, which results in patients having to replace the lost insulin with multiple daily injections.

4 Mar 2022

Study identifies new ways to enhance SC-beta cell survivability through genetic manipulation

Recent advances in the transplantation of stem cell-derived insulin-producing beta cells (SC-beta cells) to treat type 1 diabetes (T1D) has generated considerable interest and excitement.

3 Mar 2022

Study provides insight into what causes therapy failure in patients with myelodysplastic syndromes

Researchers from The University of Texas MD Anderson Cancer Center discovered that treatment resistance in patients with myelodysplastic syndromes (MDS) is caused by two distinct classes of stem cells and identified possible therapeutic approaches that target these cells.

3 Mar 2022

Researchers reveal unique signature of genes expressed by hematopoietic stem cells

Hematopoietic stem cells (HSCs) have the capacity to both self-renew and differentiate into all mature blood cell types, making them promising treatments for a variety of diseases.

2 Mar 2022

Intestinal cells can change specializations during their lives, finds study

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes.

1 Mar 2022

Study explores dictionary learning-based bridge integration method for data harmonization of single-cell analysis

In a new study, researchers developed and elucidated a ‘bridge integration’ method to harmonize single-cell ribonucleic acid sequencing datasets.

1 Mar 2022

Novel molecular pathway shared by two neurodegenerative disorders discovered

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

28 Feb 2022

Novel mechanism that connects circadian rhythm and muscle repair discovered

Northwestern Medicine investigators have discovered a novel mechanism that connects circadian rhythm-controlled cellular metabolism and regeneration with muscle repair after injury, according to recent findings published in the journal Genes and Development.

28 Feb 2022

Stem Cells News and Research

Further Reading

Cell fusion could be a potential therapeutic strategy to treat retinal damage

Mason scientists receive DOD funding for breast cancer prevention and treatment research

Using mRNA to introduce gene editor into human muscle stem cells

Study raises hopes for effective treatment of infant B acute lymphoblastic leukemia

Single protein elicits multilineage reprogramming of astrocytes in adult mouse brains

Study identifies new immune checkpoint that may be exploited for cancer treatment

How have human organoids been used in research to study SARS-CoV-2?

Some blood cells remain in tissues for years, research finds

Slowing down the DNA replication speed increases cell reprogramming efficiency

World Trade Center responders have increased levels of mutations that escalate blood cancer risk

Study uncovers new clues about the cellular processes that can lead to androgen deficiency

Researchers design a peptide hydrogel for cell spheroids production

Researchers take pioneering efforts to optimize the functionality of pancreatic cells produced from stem cells

Study identifies new ways to enhance SC-beta cell survivability through genetic manipulation

Study provides insight into what causes therapy failure in patients with myelodysplastic syndromes

Researchers reveal unique signature of genes expressed by hematopoietic stem cells

Intestinal cells can change specializations during their lives, finds study

Study explores dictionary learning-based bridge integration method for data harmonization of single-cell analysis

Novel molecular pathway shared by two neurodegenerative disorders discovered

Novel mechanism that connects circadian rhythm and muscle repair discovered

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