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Prolonged exposure to air pollution can have visible, negative effects on brain

Long-term exposure to air pollution can lead to physical changes in the brain, as well as learning and memory problems and even depression, new research in mice suggests.

5 Jul 2011

Never smokers' lung adenocarcinomas show greater genome instability

Lung adenocarcinomas in people who have never smoked show greater genome instability than those in smokers, supporting the theory that lung cancer in never smokers arises through different pathways, according to research presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer.

5 Jul 2011

Patients with high EGFR expression more likely to benefit from cetuximab plus chemotherapy

High epidermal growth factor receptor expression was a good predictor of which lung cancer patients would survive longer when cetuximab was added to first-line chemotherapy, according to research presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer.

5 Jul 2011

Study: Threatened miscarriages complicate 20% of all pregnancies

Dr Kaltum Adam, an honorary clinical research fellow at St Mary's Hospital in Manchester (UK), told the annual meeting of the European Society for Human Reproduction and Embryology that around 20% of all pregnancies were complicated by threatened miscarriage, and up to 20% of these would miscarry.

5 Jul 2011

Cleavage stage embryo with aneuploidy can undergo genetic normalisation process

Professor William G. Kearns told the annual meeting of the European Society of Human Reproduction and Embryology that a three-day-old embryo with an incorrect number of chromosomes was capable of undergoing "a dynamic process of genetic normalisation" so that by day five, when it had developed to the blastocyst stage, it had become euploid, with the correct number of chromosomes.

5 Jul 2011

PET imaging technique may identify TKI-responsive lung cancer

A non-invasive PET imaging technique may identify lung cancers that respond best to tyrosine kinase inhibitors (TKIs), allowing doctors to better select patients for personalized therapy, according to research presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer.

5 Jul 2011

LCMC finds 9.6% of lung cancer patients with ALK rearrangement

ALK rearrangement has been found in 9.6% of lung cancer patients tested in the Lung Cancer Mutation Consortium, and MET amplification in another 4.1%, reflecting how many patients might benefit from targeted therapies such as crizotinib, according to research presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer.

5 Jul 2011

Erlotinib phase III study results on lung cancer presented at IASLC conference

In the first phase III study to include Western lung cancer patients, first-line treatment with erlotinib (Tarceva) nearly doubled progression-free survival compared with chemotherapy, according to research presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer.

5 Jul 2011

Early childbearing impedes education among women

In almost every country, women with more education have fewer children. But does education reduce childbearing, or does childbearing get in the way of education, or both? New research by Joel E. Cohen and colleagues in Norway found that, at least among a population of Norwegian women, childbearing impeded education more than education impeded childbearing.

5 Jul 2011

ICSI study shows strong increase in first trimester pregnancy loss after the age of 38

The research, presented at the annual conference of the European Society of Human Reproduction and Embryology, also showed that rates of preclinical abortion, miscarriage and overall pregnancy loss during the first trimester remained more or less constant until the age of 34, but increased steadily from the age of 35 onwards.

5 Jul 2011

Smart nanomaterials can disrupt blood supply to cancerous tumours

Scientists at the University of Southampton have developed smart nanomaterials, which can disrupt the blood supply to cancerous tumours.

5 Jul 2011

Life satisfaction protects against coronary heart disease

While depression and anxiety have long been recognised as risk factors for heart disease, there is less certainty over the beneficial effects of a 'positive' psychological state, Now, following a study of almost 8000 British civil servants, researchers say that a satisfying life is indeed good for the heart.

5 Jul 2011

Adipose tissue might serve as target for treating obesity-related disorders

Researchers at Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) have shown that the quality - not just the quantity - of adipose, or fat, tissue is a significant contributing factor in the development of inflammation and vascular disease in obese individuals.

5 Jul 2011

Mammograms should be personalized based on woman's age, breast density

Mammograms should not be done on a one-size fits all basis, but instead should be personalized based on a woman's age, the density of her breasts, her family history of breast cancer and a number of other factors including her own values.

5 Jul 2011

Closer look at the effect military deployment has on children

Children with a parent who was deployed in the U.S. military efforts Operation Iraqi Freedom (OIF) and Operation Enduring Freedom (OEF) for longer periods were more likely than children whose parents did not deploy to receive a diagnosis of a mental health problem, according to a report published Online First today by Archives of Pediatrics and Adolescent Medicine, one of the JAMA/Archives journals.

5 Jul 2011

Autism Speaks announces significant findings from largest study of twins with ASD

Autism Speaks, the world's largest autism science and advocacy organization, joined in announcing significant findings from the largest known study of twins with autism spectrum disorder.

5 Jul 2011

Study examines long-term sexual and relationship satisfaction in couples

Cuddling and caressing are important ingredients for long-term relationship satisfaction, according to an international study that looks at relationship and sexual satisfaction throughout committed relationships, but contrary to stereotypes, tenderness was more important to the men than to the women.

5 Jul 2011

Practices associated with successful weight loss versus maintenance

A new study indicates that the practices that help people to lose weight and the practices that help them keep it off do not overlap much.

5 Jul 2011

Individuals with anorexia nervosa have elevated mortality rate

Individuals who have eating disorders have an elevated mortality rate, especially those with anorexia nervosa (AN), according to a meta-analysis of previous studies, reported in the July issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

5 Jul 2011

Anti-depressants during early pregnancy linked to increased risk of autism

Exposure to selective serotonin reuptake inhibitors anti-depressants in early pregnancy may modestly increase risk of autism spectrum disorders, according to a Kaiser Permanente study published online in the current issue of Archives of General Psychiatry.

5 Jul 2011