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Scientists create 3D-bioprinted brain model to study interaction with immune cells

Around a glioblastoma, a very aggressive brain tumor, cells of the human immune system start helping the tumor instead of attacking it. To do research on what happens in the interaction of these cells, scientists of the University of Twente now created a 3D-bioprinted mini model of the brain.

11 Feb 2019

Scientists develop novel way with genome sequences to study widespread form of malaria

Scientists at the Institute of Genome Sciences at the University of Maryland School of Medicine have developed a novel way with genome sequences to study and better understand transmission, treat and ultimately eradicate Plasmodium vivax, the most widespread form of malaria. P. vivax is a single-celled transmitted by mosquitoes.

11 Feb 2019

Hormonal cycles may make women more prone to drug addiction, higher relapse rates

Women's hormonal cycles may not only make them more prone to drug addiction but also more affected by triggers that lead to relapse, a new Vanderbilt University study revealed. The findings are especially significant since there are virtually no addiction studies in women that account for these cycles.

11 Feb 2019

Study reveals how exercise may protect against Alzheimer's disease

Athletes know a vigorous workout can release a flood of endorphins: "feel-good" hormones that boost mood. Now there's evidence that exercise produces another hormone that may improve memory and protect against Alzheimer's disease, according to a study co-led by Ottavio Arancio, MD, PhD, a researcher at Columbia University's Vagelos College of Physicians and Surgeons and Taub Institute for Research on Alzheimer's Disease and the Aging Brain.

11 Feb 2019

New research opens the way for tailored cancer drugs

New research on how cancer mutations influence a certain type of receptor on the cell membrane opens the way for the development of tailored drugs for certain cancers, such as rectal cancer and lung cancer.

11 Feb 2019

Metabolic plasticity helps metastatic cancer cells survive hostile environments

When metastatic cancer cells need to avoid a threat, they simply reprogram themselves. Rice University scientists are beginning to get a handle on how they survive hostile environments.

8 Feb 2019

Novel protein sensor allows researchers to observe nicotine's movements in cells

When a person takes a puff on a cigarette, nicotine floods into the brain, latching onto receptors on the surface of neurons and producing feelings of happiness. But nicotine does not simply stay on the surface of cells--the drug actually permeates into neural cells and alters them from the inside out.

8 Feb 2019

Changing nature of opioid epidemic could be responsible for increase in overdose deaths

The opioid epidemic in the United States could be responsible for 700,000 overdose deaths between 2016 and 2025, according to a new study published today in JAMA Network Open.

8 Feb 2019

'Trojan horse' drug shows promise for untreatable cancers

A new cancer drug that uses a ‘Trojan horse’ approach to destroy cancer cells from within has shown promising results for patients with untreatable cancers.

8 Feb 2019

Unexpected discovery points to potential new treatment for autoimmune disorder

Researchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid arthritis that may help explain the painful flare-ups associated with the disease.

8 Feb 2019

Researchers report promising advance in the search for new class of antidepressants

In experiments with mice, researchers at Johns Hopkins Medicine report a promising advance in the search for a new class of drugs to treat major depression.

8 Feb 2019

What ‘dope sick’ really feels like

Detoxing off heroin or opioids without medication is sheer hell. I should know. For many users, full-blown withdrawal is often foreshadowed by a yawn, or perhaps a runny nose, a sore back, sensitive skin or a restless leg. For me, the telltale sign that the heroin was wearing off was a slight tingling sensation when I urinated.

8 Feb 2019

Therapy derived from parasitic worms helps protect against one of chemotherapy's side effects

A therapy derived from the eggs of parasitic worms helps to protect against one of chemotherapy's debilitating side effects by significantly downregulating major proinflammatory pathways and reducing inflammation, indicates the first transcriptome-wide profiling of the bladder during ifosfamide-induced hemorrhagic cystitis.

8 Feb 2019

New clinical trial aims to examine safety and use of two HIV prevention tools

A clinical trial has begun to examine the safety and use of two HIV prevention tools--oral pre-exposure prophylaxis and a vaginal ring--in adolescent girls and young women in southern Africa.

8 Feb 2019

New simulations offer insights on vital atomic-scale drug-cardiac cells interactions

To unravel the mysterious mechanisms of drug potency for the treatment of cardiac arrhythmias, a group of researchers at UC Davis have developed novel simulations that provide insights on vital atomic-scale drug-cardiac cells interactions.

8 Feb 2019

Study shows precision medicines could aid more breast cancer patients via RNA-targeting

When women or men receive the worrisome diagnosis of breast cancer, that news comes with an important piece of information, namely, whether their cancer is HER2-positive or HER2-negative.

8 Feb 2019

FDA takes initiative to adopt modern technologies for enhancing security of the drug supply chain

A key element of the U.S. Food and Drug Administration's mission is focused on helping to ensure that all products we regulate, including drugs available to consumers, are safe and of high quality. This means working to ensure greater accountability in our nation's drug supply chain.

8 Feb 2019

Vilcek Foundation prizes awarded to immigrants for their work on human biology and disease

The Vilcek Foundation is pleased to announce the winners of the 2019 Vilcek Foundation Prizes for Biomedical Science, awarded to immigrants who have made significant contributions to the field. Dr. Angelika Amon will receive the $100,000 Vilcek Prize, while Drs. Amit Choudhary, Jeanne T. Paz, and Mikhail G. Shapiro will each receive the $50,000 Vilcek Prize for Creative Promise.

8 Feb 2019

Inaccurate tests carried out on tuberculosis patients lead to high mortality rate

Inaccurate tests carried out on tuberculosis patients in developing countries often fail to reliably detect resistance to drugs, leading to incorrect treatment and a higher mortality rate.

8 Feb 2019

Intensive blood pressure lowering does not improve post-stroke recovery in clot-buster-treated patients

Intensive blood pressure lowering safely reduced the risk of bleeding in the brain in ischemic stroke patients being treated with clot-busting drugs, but did not improve post-stroke recovery, according to late breaking science presented at the American Stroke Association's International Stroke Conference 2019, a world premier meeting for researchers and clinicians dedicated to the science and treatment of cerebrovascular disease.

8 Feb 2019

Drugs News and Research

Scientists create 3D-bioprinted brain model to study interaction with immune cells

Scientists develop novel way with genome sequences to study widespread form of malaria

Hormonal cycles may make women more prone to drug addiction, higher relapse rates

Study reveals how exercise may protect against Alzheimer's disease

New research opens the way for tailored cancer drugs

Metabolic plasticity helps metastatic cancer cells survive hostile environments

Novel protein sensor allows researchers to observe nicotine's movements in cells

Changing nature of opioid epidemic could be responsible for increase in overdose deaths

'Trojan horse' drug shows promise for untreatable cancers

Unexpected discovery points to potential new treatment for autoimmune disorder

Researchers report promising advance in the search for new class of antidepressants

What ‘dope sick’ really feels like

Therapy derived from parasitic worms helps protect against one of chemotherapy's side effects

New clinical trial aims to examine safety and use of two HIV prevention tools

New simulations offer insights on vital atomic-scale drug-cardiac cells interactions

Study shows precision medicines could aid more breast cancer patients via RNA-targeting

FDA takes initiative to adopt modern technologies for enhancing security of the drug supply chain

Vilcek Foundation prizes awarded to immigrants for their work on human biology and disease

Inaccurate tests carried out on tuberculosis patients lead to high mortality rate

Intensive blood pressure lowering does not improve post-stroke recovery in clot-buster-treated patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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