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First Edition: June 7, 2011

Reporting for Kaiser Health News, in collaboration with The Washington Post, Sandra Boodman writes: "Being in a hospital at night or over a weekend can be hazardous to your health, and even has a name: 'the weekend effect.' A raft of studies has documented higher rates of death, complications and medical errors affecting patients treated at night or on weekends".

7 Jun 2011

Merck, Roche partner to develop cancer diagnostic assays

Merck, known outside the United States and Canada as MSD, and Roche today announced that they have entered into a collaboration focused on the application and development of diagnostic assays for use with Merck's investigational cancer therapy portfolio.

From Roche Sequencing and Life Science 7 Jun 2011

Key heart failure therapies could prevent nearly 68,000 deaths each year

A national study has found that nearly 68,000 deaths potentially could be prevented each year by optimally implementing key national guideline-recommended therapies, including critical medications and cardiac devices, for all eligible heart failure patients.

7 Jun 2011

LWW sponsors 26th Annual Clinical Symposium on Advances in Skin & Wound Care

The 26th Annual Clinical Symposium on Advances in Skin & Wound Care: The Conference for Prevention and Healing will be held September 9-12, 2011, at the Gaylord National Hotel & Convention Center, National Harbor, MD.

7 Jun 2011

Novel technique promises to reduce damage after heart attack

Scientists at the University of Leicester are investigating a novel technique that promises to protect heart muscle from life-threatening damage following a heart attack - simply by squeezing an arm. Heart attacks are the major cause of premature death in England, with massive implications for survival and costs of long-term health care.

7 Jun 2011

Study provides epidemiology of fatal occupational traumatic brain injury in the U.S.

Although traumatic brain injury (TBI) is one of the leading causes of death in the United States, work-related TBI has not been well documented. In a study published in the July issue of the American Journal of Preventive Medicine, researchers describe the epidemiology of fatal TBI in the US workplace between 2003 and 2008.

7 Jun 2011

$Zoledronate at lower dose effective in reducing risk of osteoporotic fractures$

Zoledronate at lower dose effective in reducing risk of osteoporotic fractures

A lower dose of zoledronic acid than currently recommended for prevention of bone fractures due to osteoporosis decreases bone resorption and increases bone density, and may be effective in reducing the risk of osteoporotic fractures, a study finds.

7 Jun 2011

MMV honors UT Southwestern with Project of the Year for new anti-malarial drug discovery

The discovery of a potential new anti-malarial drug by a UT Southwestern Medical Center-led research team has been awarded Project of the Year by Medicines for Malaria Venture.

7 Jun 2011

CWRU researcher helps combat mental illness in U.S. teens

When teens start experiencing changes in moods or emotions, they tend to fear sharing their blue days with their families and adults who can help them. As a consequence, they often suffer in silence.

7 Jun 2011

Tβ4 activates Akt survival kinase and reduces heart attack damage

RegeneRx Biopharmaceuticals, Inc. has announced that researchers have shown that Tβ4 has more extensive beneficial effects on the myocardium after heart attack than previously reported.

7 Jun 2011

Moving Met molecules from inside to outside of the cell could halt cancer growth

Work by researchers at Queen Mary, University of London could point to a new way to treat aggressive types of cancer.

7 Jun 2011

Unique clinical trial addresses important questions about treating AIDS-related cancers

As the world marks the 30-year anniversary of the first reporting of HIV/AIDS, now comes the realization of a new challenge for people with the incurable disease. For reasons not yet clear, people with HIV face a higher rate of cancers not usually associated with HIV. This increasing rate of "non-AIDS defining cancers" includes lung, head and neck, liver, kidney, and anal cancers, among others.

7 Jun 2011

Ligand's LGD-4033 Phase I clinical trial data presented at the Endocrine Society annual meeting

Ligand Pharmaceuticals Incorporated today announced that data from a comprehensive Phase I multi-dose program with its selective androgen receptor modulator (SARM) LGD-4033 was featured in a poster presentation today at the Endocrine Society Annual Meeting in Boston, June 4-7, 2011.

7 Jun 2011

Independent investigators report Lymphoseek meets all endpoints in NEO3-09 Phase 3 study

Independent investigators reported today full results from the NEO3-09 study, reaffirming earlier top-line results that showed Lymphoseek met all primary and secondary endpoints and exhibited superior performance to vital blue dye in intraoperative lymphatic mapping (ILM) procedures.

7 Jun 2011

Increased blood clotting tendency linked to elevated bowel cancer risk

Back in the mid 19th century, a French doctor, Armand Trousseau, discovered a connection between cancer and thrombosis - the formation of often dangerous blood clots that can lead to venous occlusion.

7 Jun 2011

New poll finds 63% of Massachusetts residents support health care law enacted in 2006

A new poll by the Harvard School of Public Health and The Boston Globe finds 63% of Massachusetts residents support the health care reform legislation enacted in 2006, 21% oppose it while 6% are not sure and 9% have not heard or read about the law.

7 Jun 2011

Study finds consistent link between Parkinson's disease and melanoma

An analysis of several studies shows that people with Parkinson's disease have a significantly higher risk of melanoma, the most dangerous type of skin cancer and the leading cause of death from skin diseases.

7 Jun 2011

Ridaforolimus Phase III SUCCEED clinical trial on metastatic sarcoma meets primary endpoint

Merck, known outside the United States and Canada as MSD, and ARIAD Pharmaceuticals, Inc.,, today announced the presentation of detailed results from the Phase III SUCCEED clinical trial. SUCCEED evaluated oral ridaforolimus, an investigational mTOR inhibitor, in patients with metastatic soft-tissue or bone sarcomas who previously had a favorable response to chemotherapy.

7 Jun 2011

Consumption of high-fat food causes more insulin to be released by the pancreas and leads to obesity

Fat-rich food makes you fat. Behind this simple equation lie complex signalling pathways, through which the neurotransmitters in the brain control the body's energy balance.

7 Jun 2011

Race impacts risk of heart disease after gestational diabetes

New research finds that gestational diabetes, or pregnancy-related diabetes, may not raise the risk of heart disease independent of other cardiovascular risk factors except in certain high-risk populations, such as Hispanics. The results will be presented Monday at The Endocrine Society's 93rd Annual Meeting in Boston.

7 Jun 2011

Research News and Research

First Edition: June 7, 2011

Merck, Roche partner to develop cancer diagnostic assays

Key heart failure therapies could prevent nearly 68,000 deaths each year

LWW sponsors 26th Annual Clinical Symposium on Advances in Skin & Wound Care

Novel technique promises to reduce damage after heart attack

Study provides epidemiology of fatal occupational traumatic brain injury in the U.S.

Zoledronate at lower dose effective in reducing risk of osteoporotic fractures

MMV honors UT Southwestern with Project of the Year for new anti-malarial drug discovery

CWRU researcher helps combat mental illness in U.S. teens

Tβ4 activates Akt survival kinase and reduces heart attack damage

Moving Met molecules from inside to outside of the cell could halt cancer growth

Unique clinical trial addresses important questions about treating AIDS-related cancers

Ligand's LGD-4033 Phase I clinical trial data presented at the Endocrine Society annual meeting

Independent investigators report Lymphoseek meets all endpoints in NEO3-09 Phase 3 study

Increased blood clotting tendency linked to elevated bowel cancer risk

New poll finds 63% of Massachusetts residents support health care law enacted in 2006

Study finds consistent link between Parkinson's disease and melanoma

Ridaforolimus Phase III SUCCEED clinical trial on metastatic sarcoma meets primary endpoint

Consumption of high-fat food causes more insulin to be released by the pancreas and leads to obesity

Race impacts risk of heart disease after gestational diabetes

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