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Scientists discover key molecule that targets tumour blood vessels

Scientists at the Walter and Eliza Hall Institute have discovered a key molecule needed to kill the blood vessels that supply tumours.

7 Jun 2011

Millennium, Seattle Genetics' new brentuximab vedotin trial data presented at ASCO 2011

Seattle Genetics, Inc. and Millennium: The Takeda Oncology Company, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, today reported updated data from a pivotal trial of brentuximab vedotin in relapsed or refractory Hodgkin lymphoma and a phase II trial in relapsed or refractory systemic anaplastic large cell lymphoma.

7 Jun 2011

Women with higher leptin levels have fewer symptoms of depression

Women who have higher levels of the appetite-controlling hormone leptin have fewer symptoms of depression, and this apparent inverse relationship is not related to body mass index (BMI), a new study finds.

7 Jun 2011

Faults in p53 gene could help predict beneficial drug combination for ovarian cancer

FAULTS in a gene commonly inactivated in many different types of cancer could be used to predict which drug combination ovarian cancer patients are most likely to benefit from, according to results presented at the American Society for Clinical Oncology.

7 Jun 2011

Specific forms of lymphoma create their own survival niche

Cancer cells do not grow equally well everywhere in the body. Often, they first create the conditions in which they can grow. Many years ago researchers discovered that solid tumors attract blood vessels to ensure their supply of nutrients by secreting specific factors.

7 Jun 2011

Sprouts suspected as possible source of German E. coli outbreak

German officials on Sunday said an E. coli strain that has sickened more than 2,000 people and killed 22 may have originated in a batch of sprouts produced at an organic farm in the north of the country, the New York Times reports.

7 Jun 2011

Exelixis reports encouraging interim data from cabozantinib phase 2 trial for metastatic CRPC

Exelixis, Inc. today reported updated interim data from the fully enrolled cohort of patients with metastatic castration-resistant prostate cancer (CRPC) treated with cabozantinib (XL184) in a phase 2 adaptive randomized discontinuation trial (RDT).

7 Jun 2011

Silencing two microRNAs may help treat age-related macular degeneration

Blocking two tiny molecules of RNA - a chemical cousin of DNA - appears to suppress the abnormal growth of blood vessels that occurs in degenerative eye disorders, UT Southwestern Medical Center researchers have found.

7 Jun 2011

Former Malian health minister indicted in case about misuse of global fund donations

Oumar Ibrahim Toure, a former Malian health minister, "has been indicted for his role over the misuse of donor funds to fight malaria and tuberculosis in the poor West African nation, Mali's supreme court said in a statement" on Thursday, Reuters reports.

7 Jun 2011

ImaginAb, Oxford BioMedicaplc enter research deal to develop in vivo diagnostic imaging agent

Oxford BioMedicaplc, a leading gene therapy company, today announces that it has signed a research collaboration agreement with ImaginAb, Inc., a biotechnology company specialising in the development of engineered antibody fragments for diagnostic imaging and novel therapeutic applications, to engineer an in vivo diagnostic imaging agent using an antibody targeting the Company's proprietary 5T4 tumour antigen.

7 Jun 2011

Moderate consumption of desserts with low glycemic index and glycemic load may help treat pediatric obesity

Overweight girls lose more weight and can better stay on a healthy diet if they eat sugar-free, low-fat desserts several times weekly, as opposed to any dessert once a week, a new study finds. The results will be reported Monday at The Endocrine Society's 93rd Annual Meeting in Boston.

7 Jun 2011

Non-steroidal, oral contraceptive for men

Researchers at Columbia University Medical Center are honing in on the development of what may be the first non-steroidal, oral contraceptive for men. Tests of low doses of a compound that interferes with retinoic acid receptors (RARs), whose ligands are metabolites of dietary vitamin A, showed that it caused sterility in male mice.

7 Jun 2011

Female cancer survivors benefit from natural nutritional supplement

A natural nutritional supplement, marketed for the last decade as a sexual aid, has been shown to significantly improve overall quality of life for female cancer survivors, according to researchers at Wake Forest Baptist Medical Center.

7 Jun 2011

Symphogen's Sym004 Phase 1 trial data on advanced solid tumors presented at ASCO 2011

Symphogen announced today preliminary primary endpoint data on 12 of 20 patients enrolled in the first Phase 1 clinical trial with their lead cancer compound, Sym004.

7 Jun 2011

Testosterone spray may slow cognitive decline in post-menopausal women

Post-menopausal women have better memory after daily treatment with a testosterone spray for six months, a new preliminary study finds. The results will be presented Saturday at The Endocrine Society's 93rd Annual Meeting in Boston.

7 Jun 2011

Researchers reveal surprising link between cell's skeleton and organ size

A group of scientists at the Instituto Gulbenkian de Ci-ncia, in Portugal, have uncovered a surprising link between the cell's skeleton and organ size. The team, led by Florence Janody, show in the journal Development, that one of the proteins that regulates the skeleton of the cell also acts to blocks activation of genes that promote cell survival and proliferation.

7 Jun 2011

Thermo Fisher Scientific unveils three new mass spectrometry products at 59th Annual ASMS Conference

Thermo Fisher Scientific Inc., the world leader in serving science, introduced three breakthrough instruments that take mass spectrometry (MS) analysis to new levels of performance in resolution, speed, sensitivity and accuracy. The new instruments were unveiled at the 59th Annual ASMS Conference on Mass Spectrometry and Allied Topics, being held June 5-9 at the Colorado Convention Center.

From Thermo Fisher Scientific Inc. 7 Jun 2011

Jindal's Medicaid plan questioned; Wash. lawmakers enact fee on nursing homes to increase federal match

Calling it a "dubious privatization venture," a Baton Rouge good-government group last week questioned Gov. Bobby Jindal's plan to turn over large chunks of the state Medicaid program to private insurers and praised the Louisiana House of Representatives for trying to slow the process.

7 Jun 2011

Manhattan acquires Senior Scientific

In a move to accelerate applications of a novel cancer detection and treatment technology, Manhattan Scientifics today announced that it has acquired all of Senior Scientific, LLC and its affiliate Scientific Nanomedicine Inc.

7 Jun 2011

Gay, bisexual teenagers more likely to engage in risky behavior

A new report finds that gay, lesbian and bisexual high school students are more likely than heterosexual students to engage in such risky behavior as smoking, drinking alcohol and carrying guns. The study by the Centers for Disease Control and Prevention (CDC) surveyed 156,000 high school students and was released on Monday. This is the largest of its kind by the federal government.

7 Jun 2011

Research News and Research

Scientists discover key molecule that targets tumour blood vessels

Millennium, Seattle Genetics' new brentuximab vedotin trial data presented at ASCO 2011

Women with higher leptin levels have fewer symptoms of depression

Faults in p53 gene could help predict beneficial drug combination for ovarian cancer

Specific forms of lymphoma create their own survival niche

Sprouts suspected as possible source of German E. coli outbreak

Exelixis reports encouraging interim data from cabozantinib phase 2 trial for metastatic CRPC

Silencing two microRNAs may help treat age-related macular degeneration

Former Malian health minister indicted in case about misuse of global fund donations

ImaginAb, Oxford BioMedicaplc enter research deal to develop in vivo diagnostic imaging agent

Moderate consumption of desserts with low glycemic index and glycemic load may help treat pediatric obesity

Non-steroidal, oral contraceptive for men

Female cancer survivors benefit from natural nutritional supplement

Symphogen's Sym004 Phase 1 trial data on advanced solid tumors presented at ASCO 2011

Testosterone spray may slow cognitive decline in post-menopausal women

Researchers reveal surprising link between cell's skeleton and organ size

Thermo Fisher Scientific unveils three new mass spectrometry products at 59th Annual ASMS Conference

Jindal's Medicaid plan questioned; Wash. lawmakers enact fee on nursing homes to increase federal match

Manhattan acquires Senior Scientific

Gay, bisexual teenagers more likely to engage in risky behavior

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