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Targeting Sirt-1 enzyme shows promise in controlling graft-vs-host disease

Bone marrow transplant offers patients with leukemia and lymphoma a potentially curative treatment. Bone marrow from the donor contains healthy immune cells, whose mission is to protect the body from invaders.

28 Jan 2019

Injection of genetically modified virus effectively treats metastatic melanoma patients

Injection of a genetically modified virus that induces the body's own immune cells to attack metastatic melanoma effectively treated almost 40 percent of patients with tumors that could not be surgically removed, according to researchers from three prominent cancer centers in a study published as an "article in press" on the Journal of the American College of Surgeons website in advance of print publication.

28 Jan 2019

Researchers create synthetic growth factor that offers comparable biological response

Growth factors are ligands that play important roles in the body - they are responsible for tissue regeneration, wound healing, and the maintenance and growth of cells.

28 Jan 2019

Low doses of anti-HIV drug appear to reduce tau protein in neurons of Alzheimer’s patients

The accumulation of amyloid beta plaques and tangles of a protein called tau in the brain are hallmarks of Alzheimer's disease.

27 Jan 2019

Regular use of aspirin may help some patients survive head and neck cancer

Regular use of aspirin or other nonsteroidal anti-inflammatory drugs may help some patients with head and neck cancer survive the disease, according to a study led by Professor Jennifer Grandis at the University of California, San Francisco.

27 Jan 2019

Association between tobacco use and paranoia is largely due to shared genetic influences

Paranoia is associated with regular tobacco smoking in adolescents after accounting for other factors like cannabis use, sleep disturbances and stressful life events, reports a study recently published to the Journal of the American Academy of Child and Adolescent Psychiatry.

25 Jan 2019

Scientists pinpoint mechanism that leads to steroid diabetes

Patients undergoing long-term treatment with steroids may suffer from metabolic side effects. Researchers at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich, partners in the German Center for Diabetes Research, have now pinpointed a mechanism that leads to so-called steroid diabetes

25 Jan 2019

New study uncovers key protein in the production of insulin

The crucial hormone insulin needs help acquiring the right structure. A protein that assists in the process of insulin folding has just been discovered in a new study conducted by researchers at the Department of Biomedical Sciences, University of Copenhagen.

25 Jan 2019

Regular use of common pain relief medicines improves survival for head and neck cancer patients

Regular use of a common type of medication, such as aspirin and ibuprofen, significantly improves survival for a third or more patients with head and neck cancer, a new study led by UC San Francisco has found.

25 Jan 2019

Fish oil does not appear to provide therapeutic benefits for obese teens with uncontrolled asthma

Fish oil does not appear to improve asthma control in adolescents and young adults with uncontrolled asthma who are overweight or obese, according to new research published online in the Annals of the American Thoracic Society.

25 Jan 2019

Scientists develop new method for synthesizing para-carboxyplenylsiloxanes

Russian scientists have developed a new method for synthesizing para-carboxyplenylsiloxanes, a unique class of organosilicon compounds. The resulting compounds are promising for creating self-healing, electrically conductive, heat- and frost-resistant silicones.

25 Jan 2019

Combination of cystic fibrosis drugs found to be safe and effective in children aged 2-5 years

An open label Phase 3 study conducted at Ann & Robert H. Lurie Children's Hospital of Chicago and other centers established that a combination of cystic fibrosis drugs lumacaftor and ivacaftor is safe and effective in children aged 2-5 years, whose disease is caused by two copies of F508del-CFTR gene mutation - the most common and severe form of cystic fibrosis.

25 Jan 2019

Researchers find promising technique for estimating rural intravenous drug use

A study published today in the American Journal of Public Health estimates that 1,857 people injected drugs in the last six months in Cabell County, W.Va., a rural county with a population of 94,958. This estimate is based on an innovative survey technique that public health officials can now use in their own rural communities to address the opioid epidemic.

25 Jan 2019

New study solves mystery behind how proteins interact with cell membrane

Trillions of cells -- all different shapes and sizes -- form a human body's structure. Surrounding each cell is a membrane, jointly acting as hostess and security -- welcoming certain information into the cell while making sure its components don't spill out into the body's void.

25 Jan 2019

Drought in rural Lesotho increases HIV risk among adolescent girls

Adolescent girls exposed to severe drought conditions in rural Lesotho had higher rates of HIV, according to a new study led by researchers at ICAP at Columbia University, a global health organization based at the Columbia Mailman School of Public Health, and from the Lesotho Ministry of Health and U.S. Centers for Disease Control and Prevention.

25 Jan 2019

Discovery could guide future treatments for patients with hypertension

A team of Vanderbilt University Medical Center researchers, working with the U.S. Department of Veteran's Affairs, has discovered genetic associations with blood pressure that could guide future treatments for patients with hypertension.

25 Jan 2019

Reassuring findings on the link between antidepressants and fertility

Based on limited research, there's no strong evidence that selective serotonin-reuptake inhibitors (SSRIs) - the most widely used class of antidepressants - have an adverse impact on fertility, according to a paper in the Harvard Review of Psychiatry.

25 Jan 2019

Drugs News and Research

Targeting Sirt-1 enzyme shows promise in controlling graft-vs-host disease

Injection of genetically modified virus effectively treats metastatic melanoma patients

Researchers create synthetic growth factor that offers comparable biological response

Low doses of anti-HIV drug appear to reduce tau protein in neurons of Alzheimer’s patients

Regular use of aspirin may help some patients survive head and neck cancer

Association between tobacco use and paranoia is largely due to shared genetic influences

Scientists pinpoint mechanism that leads to steroid diabetes

New study uncovers key protein in the production of insulin

Regular use of common pain relief medicines improves survival for head and neck cancer patients

Fish oil does not appear to provide therapeutic benefits for obese teens with uncontrolled asthma

Scientists develop new method for synthesizing para-carboxyplenylsiloxanes

Combination of cystic fibrosis drugs found to be safe and effective in children aged 2-5 years

Researchers find promising technique for estimating rural intravenous drug use

New study solves mystery behind how proteins interact with cell membrane

Drought in rural Lesotho increases HIV risk among adolescent girls

Discovery could guide future treatments for patients with hypertension

Reassuring findings on the link between antidepressants and fertility

ACR expresses its continuing concern with recent CMS policy

Researchers unlock key process in human cells that contributes to cancer, neurodegenerative diseases, and aging

Nine early career scientists named 2019 recipients of the Damon Runyon-Rachleff Innovation Award

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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