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FDA approves new treatment for rare disease of the bone marrow and blood

The U.S. Food and Drug Administration today approved Elzonris (tagraxofusp-erzs) infusion for the treatment of blastic plasmacytoid dendritic cell neoplasm in adults and in pediatric patients, two years of age and older.

21 Dec 2018

New approach to destroy HIV reservoirs

Current HIV treatments need to be taken for life by those infected as antiretroviral therapy is unable to eliminate viral reservoirs lurking in immune cells. Institut Pasteur scientists have identified the characteristics of CD4 T lymphocytes that are preferentially infected by the virus - it is their metabolic (or energy-producing) activity1 that enables the virus to multiply.

21 Dec 2018

Interval of time to biochemical failure could be used as surrogate endpoint for prostate cancer

An analysis of the NRG Oncology clinical trial NRG-RTOG 9202 showed that the interval of time to biochemical failure, or the time it takes for previously treated cancer to return as indicated by prostate specific antigen rise, could be used as a surrogate endpoint for locally advanced prostate cancer.

21 Dec 2018

GW researchers receive NIH funding to study causes of high risk of heart disease in HIV patients

Atherosclerosis and cardiovascular disease are major complications of HIV infection and cannot currently be treated by antiretroviral treatments.

21 Dec 2018

New project develops more efficient treatment approaches for cardiovascular diseases

Within the framework of a European collaborative research project, Oliver Müller, professor at the Faculty of Medicine at Kiel University and Consultant at the Department of Internal Medicine III, University Medical Center Schleswig-Holstein, Campus Kiel, will receive 1.4 million Euros for the project "CardioReGenix: Development of Next-Generation Gene Therapies for Cardiovascular Disease".

21 Dec 2018

Study provides information about chemotherapeutic drugs binding to plasma proteins

Chemotherapy is use of drugs to cure a disease but more specifically, it refers to drug therapy for cancer. Cancer chemotherapy can be done with a single drug or a combination of drugs and is usually systematic in nature, that is to say that a drug is administered through the blood circulation to eliminate cancer cells in many parts of the body.

21 Dec 2018

Elegant, low-cost approach enhances single-cell RNA sequencing

Droplet microfluidics has revolutionized single-cell RNA sequencing, offering a low-cost, high-throughput method for single-cell genomics. However, this method has been limited in its ability to capture complete RNA transcription information.

20 Dec 2018

Experimental gene therapy extends lifespan of mice suffering from untreatable mitochondrial disease

Researchers at the University of Helsinki and Folkhälsan Research Center have, together with their collaborators, for the first time demonstrated in a mouse model that partial restoration of respiratory chain function in mitochondria, which serve as cellular power plants, may be sufficient to entirely prevent symptoms of a severe mitochondrial disorder.

20 Dec 2018

Advanced stem cell approach could help fight Parkinson's disease

Scientists have taken a key step towards improving an emerging class of treatments for Parkinson's disease.

20 Dec 2018

Using mobile phone-based intervention to encourage Chinese smokers to quit the habit

Among smokers receiving a 12-week-long mobile phone-based intervention encouraging them to quit, up to 6.5% of participants stopped smoking by the end of the study, according to a research article published this week in the open-access journal PLOS Medicine by Jinsong Tang of the Second Xiangya Hospital of Central South University in China, and colleagues.

20 Dec 2018

Women with heart disease report more disparities in care compared with men

Using data from a nationwide survey that represents 11 million women with heart and blood vessel diseases, Johns Hopkins Medicine researchers say women continue to report significant disparities in the care they receive compared with men.

20 Dec 2018

Scientists investigate potential of nanomaterials to activate the body's antitumor immune response

The importance of research into the role of the immune system in the development and therapy of oncological diseases was emphasized by the Royal Swedish Academy, which recently named James Allison and Tasuku Honjo recipients of the 2018 Nobel Prize in Physiology or Medicine for launching an effective new way to attack cancer by treating the immune system rather than the tumor.

20 Dec 2018

$Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction$

Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction

Researchers at the University of Arizona have discovered that metformin, a drug commonly used to treat type 2 diabetes, might also be used to treat heart failure with preserved ejection fraction, a condition that is predicted to affect over 8% of people ages 65 or older by the year 2020.

19 Dec 2018

Self-powered bandage generates electricity, reduces healing time for skin wounds in rats

Skin has a remarkable ability to heal itself. But in some cases, wounds heal very slowly or not at all, putting a person at risk for chronic pain, infection and scarring. Now, researchers have developed a self-powered bandage that generates an electric field over an injury, dramatically reducing the healing time for skin wounds in rats.

19 Dec 2018

Kidney failure is increasing in Australians under 50 with type 2 diabetes, study finds

A study of more than 1.3 million Australians with diabetes has found that kidney failure is increasing in people with type 2 diabetes aged under 50 years, leading to reduced quality of life and placing growing demand on the country's kidney dialysis and transplantation services.

19 Dec 2018

Galectins play a key role in the degeneration of cartilage in osteoarthritis

A network of carbohydrate binding proteins - so-called galectins - plays an important role in the degeneration of cartilage in osteoarthritis.

19 Dec 2018

Personalization techniques give a new lease of life to anticancer vaccines

Anticancer vaccines have gained a new lease of life with techniques to personalise them to individual patients.

19 Dec 2018

Active ingredient in eye drops shows promise for treating aggressive blood cancer

An active ingredient in eye drops that were being developed for the treatment of a form of eye disease has shown promise for treating an aggressive form of blood cancer. Scientists at the Wellcome Sanger Institute, University of Cambridge, University of Nottingham and their collaborators have found that this compound, which targets an essential cancer gene, could kill leukemia cells without harming non-leukemic blood cells.

19 Dec 2018

Mind-body exercises may improve cognition in older adults

Mind-body exercises--especially tai chi and dance mind-body exercise--are beneficial for improving global cognition, cognitive flexibility, working memory, verbal fluency, and learning in older adults. The findings come from a meta-analysis of all relevant published studies.

19 Dec 2018

New study adds evidence to efficacy and safety of low-dose vaginal estrogen

Despite its proven effectiveness in treating the genital symptoms of menopause, low-dose vaginal estrogen therapy remains underused largely because of misperceptions regarding its safety.

19 Dec 2018

Therapy News and Research

FDA approves new treatment for rare disease of the bone marrow and blood

New approach to destroy HIV reservoirs

Interval of time to biochemical failure could be used as surrogate endpoint for prostate cancer

GW researchers receive NIH funding to study causes of high risk of heart disease in HIV patients

New project develops more efficient treatment approaches for cardiovascular diseases

Study provides information about chemotherapeutic drugs binding to plasma proteins

Elegant, low-cost approach enhances single-cell RNA sequencing

Experimental gene therapy extends lifespan of mice suffering from untreatable mitochondrial disease

Advanced stem cell approach could help fight Parkinson's disease

Using mobile phone-based intervention to encourage Chinese smokers to quit the habit

Women with heart disease report more disparities in care compared with men

Scientists investigate potential of nanomaterials to activate the body's antitumor immune response

Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction

Self-powered bandage generates electricity, reduces healing time for skin wounds in rats

Kidney failure is increasing in Australians under 50 with type 2 diabetes, study finds

Galectins play a key role in the degeneration of cartilage in osteoarthritis

Personalization techniques give a new lease of life to anticancer vaccines

Active ingredient in eye drops shows promise for treating aggressive blood cancer

Mind-body exercises may improve cognition in older adults

New study adds evidence to efficacy and safety of low-dose vaginal estrogen

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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