Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Scripps Florida researchers awarded $2.875 million to destroy common form of leukemia

Christoph Rader, PhD, associate professor at the Florida campus of The Scripps Research Institute, has been awarded a $2.875 million, five-year grant from the National Cancer Institute to develop unique antibody-drug conjugates engineered to eradicate one of the most common forms of leukemia, chronic lymphocytic leukemia

10 Apr 2018

Using Cord Blood to Alleviate the Symptoms of Autism

Cord blood has been studied extensively for the treatment of hematological diseases such as cancer and sickle cell anemia, but is now in phase II trials for the alleviation of autism. Dr. Ann Smith, director of Smart Cells who provided the cord blood for the trial, discusses the research and it's potential.

9 Apr 2018

Insights into blood cell formation may help break new ground in treatment of anemia

Every day, stem cells in our bone marrow produce billions of new red blood cells. Any disruption in this process can result in serious disease. Researchers from Charité - Universitätsmedizin Berlin and Harvard Medical School have succeeded in furthering our understanding of how blood cells are formed.

4 Apr 2018

MIT researchers develop new portable device to monitor white blood cell levels

One of the major side effects of chemotherapy is a sharp drop in white blood cells, which leaves patients vulnerable to dangerous infections. MIT researchers have now developed a portable device that could be used to monitor patients' white blood cell levels at home, without taking blood samples.

3 Apr 2018

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

Allogeneic bone marrow transplant (BMT) is an essential treatment to cure patients with blood cancers such as leukemia. In patients who have undergone chemotherapy and radiation, a small number of cancer cells can remain in the bloodstream and allow the malignancy to recur.

3 Apr 2018

Computational biologists develop algorithm to align datasets with single-cell resolution

A team of computational biologists has developed an algorithm that can 'align' multiple sequencing datasets with single-cell resolution.

3 Apr 2018

Combined treatment prolongs survival in mouse models of malignant mesothelioma

Combined treatment with two cancer immunotherapy drugs - one a novel immune modulator and one that focuses and activates the antitumor immune response - significantly prolonged survival in mouse models of the aggressive cancer malignant mesothelioma.

2 Apr 2018

FDA grants accelerated approval to leukemia drug for patients with MRD-positive ALL

The U.S. Food and Drug Administration granted accelerated approval to Blincyto (blinatumomab) to treat adults and children with B-cell precursor acute lymphoblastic leukemia (ALL) who are in remission but still have minimal residual disease (MRD).

30 Mar 2018

Study: Lower temperatures can trigger the body’s ‘good’ fat formation at cellular level

Lower temperatures can activate the body's 'good' fat formation at a cellular level, a new study led by academics at The University of Nottingham has found.

21 Mar 2018

Stem cell treatment may help rejuvenate ovaries, avoid effects of premature menopause

Young women with premature ovarian insufficiency may be able to use their own bone marrow stem cells to rejuvenate their ovaries and avoid the effects of premature menopause, new research suggests.

19 Mar 2018

Subset of immune cells critical for ensuring healthy weight gain, study shows

Obesity and its negative impacts on health - including metabolic syndrome, type-2 diabetes mellitus and cardiovascular complications - are a global pandemic (Taubes, 2009).

16 Mar 2018

Clinical trial to test efficacy of stem cell transplants in stopping ALS muscle deterioration

Once funding is obtained, researchers can perform a clinical trial to test the efficacy of transplanting bone marrow cells into muscles to stop deterioration caused by the illness. The method has already yielded positive results on mice.

16 Mar 2018

Young athletes commonly have bone marrow edema in lower spine, study shows

New research indicates that young recreational and elite athletes commonly accumulate excess fluid in the bone marrow around the joint that connects the spine with the pelvis.

13 Mar 2018

Newly-discovered hereditary mutation leads to increased production of EPO in the blood

A newly-discovered hereditary mutation is responsible for an increased production of erythropoietin (EPO) in the blood.

8 Mar 2018

New study shows advantages of DNA barcoding technique for identifying nanoparticles

The first direct comparison of in vitro and in vivo screening techniques for identifying nanoparticles that may be used to transport therapeutic molecules into cells shows that testing in lab dishes isn't much help in predicting which nanoparticles will successfully enter the cells of living animals.

5 Mar 2018

Leading consultants from the North East putting rare diseases expertise on world stage

This Rare Disease Day (28 February), the Academic Health Science Network, is shining a spotlight on the region’s healthcare pioneers chosen to lead three major European rare disease networks.

1 Mar 2018

Telomere length testing can alter treatment decisions for certain diseases

Research led by Johns Hopkins physicians and scientists shows that a test for measuring the length of DNA endcaps, called telomeres, which has a variability rate of 5 percent, can alter treatment decisions for patients with certain types of bone marrow failure.

27 Feb 2018

Study suggests novel approach for protecting diabetes patients from vascular disease

Recent findings suggest a novel approach for protecting people with diabetes from their higher risk of advanced blood vessel disease, which sets the stage for early heart attacks and strokes.

27 Feb 2018

UT Dallas researchers use new technique to isolate cancer stem cells

Researchers at The University of Texas at Dallas have devised a new technique to isolate aggressive cells thought to form the root of many hard-to-treat metastasized cancers -- a significant step toward developing new drugs that might target these cells.

22 Feb 2018

Scientists discover new treatment approach to curb severe myocarditis

The outcome of viral myocarditis is closely associated with the immune response of the affected individual. An inhibitor of the immunoproteasome, a protein degradation complex in immunocompetent cells, reduces the extent of the inflammation and thus also the damage to the heart during myocarditis.

22 Feb 2018

Bone Marrow News and Research

Further Reading

Scripps Florida researchers awarded $2.875 million to destroy common form of leukemia

Using Cord Blood to Alleviate the Symptoms of Autism

Insights into blood cell formation may help break new ground in treatment of anemia

MIT researchers develop new portable device to monitor white blood cell levels

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

Computational biologists develop algorithm to align datasets with single-cell resolution

Combined treatment prolongs survival in mouse models of malignant mesothelioma

FDA grants accelerated approval to leukemia drug for patients with MRD-positive ALL

Study: Lower temperatures can trigger the body’s ‘good’ fat formation at cellular level

Stem cell treatment may help rejuvenate ovaries, avoid effects of premature menopause

Subset of immune cells critical for ensuring healthy weight gain, study shows

Clinical trial to test efficacy of stem cell transplants in stopping ALS muscle deterioration

Young athletes commonly have bone marrow edema in lower spine, study shows

Newly-discovered hereditary mutation leads to increased production of EPO in the blood

New study shows advantages of DNA barcoding technique for identifying nanoparticles

Leading consultants from the North East putting rare diseases expertise on world stage

Telomere length testing can alter treatment decisions for certain diseases

Study suggests novel approach for protecting diabetes patients from vascular disease

UT Dallas researchers use new technique to isolate cancer stem cells

Scientists discover new treatment approach to curb severe myocarditis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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