Genomics News and Research

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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

Yeast reveals a key mechanism in how genes are controlled

Yeast, that simple organism essential to making beer and bread, has revealed for Cornell University researchers a key mechanism in how genes are controlled.

28 Oct 2022

Ancient viral DNA in human genomes protects cells against present-day viruses

Viral DNA in human genomes, embedded there from ancient infections, serve as antivirals that protect human cells against certain present-day viruses, according to new research.

27 Oct 2022

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest in response.

27 Oct 2022

New approach to immunotherapy provokes a robust anti-tumor immune response in preclinical models

A new approach to cancer immunotherapy that uses one type of immune cell to kill another - rather than directly attacking the cancer - provokes a robust anti-tumor immune response that shrinks ovarian, lung, and pancreatic tumors in preclinical disease models, according to researchers at the Icahn School of Medicine at Mount Sinai in New York.

25 Oct 2022

New diagnostic method applies machine learning to advanced genomics data to detect sepsis

Sepsis, the overreaction of the immune system in response to an infection, causes an estimated 20% of deaths globally and as many as 20 to 50% of U.S. hospital deaths each year.

24 Oct 2022

Breakthrough discovery is a 'major step forward' in understanding cervical cancer

Scientists have discovered that cervical cancer can be divided into two distinct molecular subgroups – one far more aggressive than the other – as part of the largest 'omics' study of its kind, led by researchers at UCL and the University of Southampton.

21 Oct 2022

Surprising discovery in people of Polynesian ancestry offers clues to genetic underpinnings of high cholesterol

The discovery of a genetic variant that is relatively common among people of Polynesian ancestry, but incredibly rare in most other populations, is giving clues to the genetic underpinnings of high cholesterol in all people, according to new research led by University of Pittsburgh School of Public Health geneticists in partnership with several other groups, including the University of Otago and the Samoan health research community.

21 Oct 2022

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

In a recent study published in the journal Nature Cell Biology, researchers demonstrated the susceptibility of salivary glands to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in vitro using an organoid culture model.

20 Oct 2022

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

In a recent study published in the journal eLife, researchers showed the utility of machine-learning models in identifying early immune signatures, which could reliably predict clinical and immunological outcomes in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-infected outpatients.

20 Oct 2022

Study uses pluripotent stem cell models to investigate stress response in PTSD patients

Stem cell-derived neurons from combat veterans with post-traumatic stress disorder (PTSD) react differently to a stress hormone than those from veterans without PTSD, a finding that could provide insights into how genetics can make someone more susceptible to developing PTSD following trauma exposure.

20 Oct 2022

Scientists map structure of the hepatitis C virus E1E2 glycoprotein complex

A team led by scientists at Scripps Research and the University of Amsterdam has achieved an important goal in virology: mapping, at high resolution, critical proteins that stud the surface of the Hepatitis C virus (HCV) and enable it to enter host cells.

20 Oct 2022

Study identifies gene mutations that impact radiation resistance and sensitivity

A new Northwestern Medicine study identifies common and rare gene mutations that impact radiation resistance and sensitivity, an important step toward providing more individualized and effective radiotherapy for patients with cancer.

20 Oct 2022

Beckman Coulter Life Sciences presenting at ASHG

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, will have a full team of dedicated professionals and informative programming at the American Society of Human Genetics (ASHG) Annual Meeting October 25-29, 2022 in Los Angeles, California at the Los Angeles Convention Center.

From Beckman Coulter Life Sciences 20 Oct 2022

Study shows how brain's sensitivity to regret may be altered in mood disorders

Researchers from the Icahn School of Medicine at Mount Sinai have learned that the way the brain processes the complex emotion of regret may be linked to an individual's ability to cope with stress, and altered in psychiatric disorders like depression.

19 Oct 2022

Scientists develop new tool to monitor brain plasticity

Scientists at Scripps Research have developed a new tool to monitor brain plasticity - the way our brains remodel and physically adapt as we learn and experience things, from watching a movie to learning a new song or language.

19 Oct 2022

BU researcher awarded $4.6 million U2C grant to develop innovative lung cancer biomarkers

Lung cancer screening by chest computed tomography (CT) can detect lung cancer earlier and make the disease less deadly; but even among nodules that are at intermediate risk, only a small minority are cancerous.

17 Oct 2022

New findings point to specific genes linked with increased risk of frozen shoulder

Frozen shoulder, or adhesive capsulitis, is a common cause of shoulder pain and immobility. New findings point to specific genes associated with an increased risk of this condition, reports The Journal of Bone & Joint Surgery.

14 Oct 2022

Metabolite discovery offers a potential way to address metabolic conditions

"Metabolism" describes the body's chemical changes that create the necessary materials for growth and overall health. Metabolites are the substances made and used during these metabolic processes - or, as a new discovery out of Scripps Research and its drug development arm, Calibr, indicates, they could also be potent molecules for treating severe diseases.

13 Oct 2022

Largest academic collaboration aims to transform the treatment for pediatric cancers

The Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute and St. Jude Children's Research Hospital today announced the largest academic collaboration of its kind to transform and accelerate the identification of vulnerabilities in pediatric cancers and translate them into better treatments.

13 Oct 2022

Study could help recommend the best treatment for women with early-stage mucinous ovarian cancer

A global study into mucinous ovarian cancer could help oncologists recommend the best treatment for women who are diagnosed early with the condition.

12 Oct 2022

Genomics News and Research

Further Reading

Yeast reveals a key mechanism in how genes are controlled

Ancient viral DNA in human genomes protects cells against present-day viruses

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

New approach to immunotherapy provokes a robust anti-tumor immune response in preclinical models

New diagnostic method applies machine learning to advanced genomics data to detect sepsis

Breakthrough discovery is a 'major step forward' in understanding cervical cancer

Surprising discovery in people of Polynesian ancestry offers clues to genetic underpinnings of high cholesterol

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

Study uses pluripotent stem cell models to investigate stress response in PTSD patients

Scientists map structure of the hepatitis C virus E1E2 glycoprotein complex

Study identifies gene mutations that impact radiation resistance and sensitivity

Beckman Coulter Life Sciences presenting at ASHG

Study shows how brain's sensitivity to regret may be altered in mood disorders

Scientists develop new tool to monitor brain plasticity

BU researcher awarded $4.6 million U2C grant to develop innovative lung cancer biomarkers

New findings point to specific genes linked with increased risk of frozen shoulder

Metabolite discovery offers a potential way to address metabolic conditions

Largest academic collaboration aims to transform the treatment for pediatric cancers

Study could help recommend the best treatment for women with early-stage mucinous ovarian cancer

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