Hemoglobin News and Research

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Quality-improvement initiatives lead to progress in diabetes care

Two major initiatives designed to improve primary care treatment of type 2 diabetes have yielded significant benefits in largely minority, disadvantaged populations, according to a pair of studies in the December issue of Medical Care.

4 Dec 2007

Wyeth receives European approval for TORISEL

Wyeth Pharmaceuticals, a division of Wyeth, has announced that the European Commission has approved TORISEL (temsirolimus) for the first-line treatment of patients with advanced renal cell carcinoma (RCC) who have at least three of six prognostic risk factors. TORISEL is the only approved cancer therapy that specifically inhibits the mTOR (mammalian target of rapamycin) kinase, an important regulator of cell proliferation, cell growth and cell survival.

27 Nov 2007

Vitamin E can significantly reduce risk of heart attacks for diabetics with certain gene variant

Vitamin E supplements can significantly reduce the risk of heart attacks and related deaths for diabetics who carry a particular version of a gene, according to researchers at the Technion-Israel Institute of Technology and the Clalit Health Services in Israel.

21 Nov 2007

New technique enables the detection of biomolecules' dynamic reactions in a single living cell

By taking advantage of the signature frequency by which organic and inorganic molecules absorb light, the team of researchers, led by Luke Lee, professor of bioengineering and director of UC Berkeley's Biomolecular Nanotechnology Center, can determine in real time whether specific enzymes are activated or particular genes are expressed, all with unprecedented resolution within a single living cell.

19 Nov 2007

New anemia measure predicts risk of death in dialysis patients

A new indicator of variations in hemoglobin level over time is a strong predictor of the risk of death among patients receiving dialysis for end-stage renal disease (ESRD), reports a study in the December Journal of the American Society of Nephrology.

15 Nov 2007

Overexpression of neuroglobin reduces severity of Alzheimer's disease in mice

Mice genetically engineered to both overproduce the protein neuroglobin and to develop Alzheimer's disease (AD) had a much milder form of the disease when compared to mice engineered to have AD alone, researchers at the Buck Institute for Age Research have reported.

13 Nov 2007

FDA strengthens warnings for erythropoiesis-stimulating agents

The U.S. Food and Drug Administration has approved revised boxed warnings and other safety-related product labeling changes for erythropoiesis-stimulating agents (ESAs), which treat certain types of anemia.

13 Nov 2007

Discovery of new hemoglobin function

A team of researchers from Wake Forest University, the National Institutes of Health and other institutions has discovered a previously undetected chemical process within the oxygen-carrying molecule hemoglobin that could have far-reaching implications for the treatment of cardiovascular diseases.

6 Nov 2007

How can some people live at high altitudes and thrive while others struggle?

The answer for Tibetans who live at altitudes around 14,000 feet is increased nitric oxide (NO) levels. High levels of NO circulate in various forms in the blood and produce the physiological mechanisms that cause the increased blood flow that maintains oxygen delivery despite hypoxia - low levels of oxygen in the ambient air and the bloodstream.

31 Oct 2007

Critical need for earlier diagnosis and referral of HIV-infected children in Africa

Care provided by nurses and other clinicians in primary health care settings in sub-Saharan Africa can result in good outcomes for children with HIV infection.

22 Oct 2007

Good outcomes possible for HIV-infected children in Africa enrolled in pediatric treatment programs

Care provided by nurses and other clinicians in primary health care settings in sub-Saharan Africa can result in good outcomes for children with HIV infection.

22 Oct 2007

Pulse cooximeters help doctors determine patients' smoking status

Pulse cooximeters have long been used to identify and measure the levels of carbon monoxide (CO) in the blood of patients or firefighters.

22 Oct 2007

Discovery of protein that plays a key role in the recycling of iron from blood

Scientists working in the only lab at MIT doing hematology research have uncovered a protein that plays a key role in the recycling of iron from blood. Their work, described in the October 11 Journal of Clinical Investigation, could lead to new therapies for certain inherited blood disorders such as beta-thalassemia, a condition that causes chronic anemia.

12 Oct 2007

Any kind of exercise helps control diabetes but combo of aerobic and resistance training the best

According to Canadian researchers any kind of exercise is better than none when it comes to controling type-2 diabetes.

18 Sep 2007

Combined aerobic and resistance training best for people with diabetes

In a new randomized controlled trial, both aerobic and resistance exercise improved glycemic/blood sugar control in people with type 2 diabetes.

18 Sep 2007

HIV patients with declining platelet counts appear to be at increased risk for HIV-associated dementia

Therapies leading to longer life for HIV patients have paradoxically increased the prevalence of this condition. Identifying biological markers for the development of HIV–associated dementia is critical both for diagnosing the disorder and for understanding its underlying mechanisms.

11 Sep 2007

Discovery of novel cause of iron overload in patients with thalassemia

According to the study, thalassemia patients overproduce a protein called GDF15, which suppresses the production of a liver protein, hepcidin, which in turn leads to an increase in the uptake of dietary iron in the gut.

30 Aug 2007

New technology for keeping liver cells alive inside bioartificial liver-assist devices

Such devices enable people who are suffering from acute liver failure to survive while their own liver cells regenerate, or until they receive a liver transplant. The person's blood or plasma circulates through the device. Inside, living cells -- usually pig or human liver cells -- perform normal liver functions.

24 Aug 2007

New techniques for measuring blood volume

The July issue of The American Journal of Medical Sciences presents a special symposium on the measurement and clinical implications of blood volume and its measurement.

16 Aug 2007

New research may lead to future gene therapies for patients with sickle cell anemia and beta-thalassemia

Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for regulating overlapping groups of genes during the development of red blood cells.

7 Aug 2007

Hemoglobin News and Research

Quality-improvement initiatives lead to progress in diabetes care

Wyeth receives European approval for TORISEL

Vitamin E can significantly reduce risk of heart attacks for diabetics with certain gene variant

New technique enables the detection of biomolecules' dynamic reactions in a single living cell

New anemia measure predicts risk of death in dialysis patients

Overexpression of neuroglobin reduces severity of Alzheimer's disease in mice

FDA strengthens warnings for erythropoiesis-stimulating agents

Discovery of new hemoglobin function

How can some people live at high altitudes and thrive while others struggle?

Critical need for earlier diagnosis and referral of HIV-infected children in Africa

Good outcomes possible for HIV-infected children in Africa enrolled in pediatric treatment programs

Pulse cooximeters help doctors determine patients' smoking status

Discovery of protein that plays a key role in the recycling of iron from blood

Any kind of exercise helps control diabetes but combo of aerobic and resistance training the best

Combined aerobic and resistance training best for people with diabetes

HIV patients with declining platelet counts appear to be at increased risk for HIV-associated dementia

Discovery of novel cause of iron overload in patients with thalassemia

New technology for keeping liver cells alive inside bioartificial liver-assist devices

New techniques for measuring blood volume

New research may lead to future gene therapies for patients with sickle cell anemia and beta-thalassemia

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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