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FDA-approved drug hampers cancer metastasis in animal model, shows study

For cancer to spread, it needs a hospitable environment in distant organs. This fertile "soil" can provide a home to circulating malignant cells.

16 Jan 2019

Multiple sclerosis could benefit from stem cell therapy

Patients with relapsing multiple sclerosis (MS) have benefited from an experimental stem cell therapy. MS is an autoimmune disease where the central nervous system is affected. It is severely debilitating and means a slow and progressive death for the patients.

16 Jan 2019

Study points to potential new biomarker and drug target for amyotrophic lateral sclerosis

Research led by stem cell scientists at Harvard University points to a potential new biomarker and drug target for amyotrophic lateral sclerosis, a neurological disease that is extremely difficult to diagnose and treat.

16 Jan 2019

Nerve transfer surgery restores arm movement in children with acute flaccid myelitis

An innovative and complex surgery involving nerve transfers is restoring hope and transforming lives torn apart by a mysterious and devastating illness. Acute flaccid myelitis, also known as AFM, strikes without warning, shows no mercy and frequently results in paralysis.

15 Jan 2019

Contraceptive patch that could provide 6 months of contraception within seconds

Most birth control methods involving hormones involve daily intake of pills. Long acting contraceptive methods that involve implants or intrauterine devices (IUDs) need regular visits to the doctor and are not as acceptable to many women.

15 Jan 2019

Researchers discover how cancer cells avoid genetic meltdown

A team of scientists have shed light on how cancer cell populations avoid genetic meltdown, despite the rapid accumulation of harmful mutations.

15 Jan 2019

Synthetic compound reverses mutant p53 aggregate accumulation, study shows

Cancer is a multidisciplinary disease, with different mutations leading to different prognoses and treatment necessities. Among the most important mutation targets in cancers, affecting more than 50% of all cancer cases, is TP53.

14 Jan 2019

Study shows how herpes viruses and tumors have learned to manipulate the same ancient RNA

Herpes viral infections use the ancient genetic material found in the human genome to proliferate, mimicking the same process tumors have been found to manipulate, Mount Sinai researchers have shown for the first time.

14 Jan 2019

Lesbian, gay and bisexual individuals more likely to suffer severe substance use disorders

Researchers know that lesbian, gay and bisexual individuals are more likely than heterosexuals to use alcohol, tobacco or other drugs, but until now they didn't know to what degree.

14 Jan 2019

Scientists identify endogenous activator of sigma-1 receptors in human cells

Cells communicate through complex mechanisms that typically involve receptors and ligands that bind to them. Endogenous ligands, produced by the body, have been identified for the vast majority of cellular receptors, helping explain receptor existence and function. But in the case of sigma-1 receptors, which interact with a diverse array of psychoactive drugs, an endogenous ligand has remained elusive.

14 Jan 2019

Turning breast cancer cells into fat cells prevents the formation of metastases

An innovative combination therapy can force malignant breast cancer cells to turn into fat cells. This can be used to prevent the formation of metastases in mice, as researchers at the University of Basel's Department of Biomedicine recently reported in the journal Cancer Cell.

14 Jan 2019

New skin patch provides long-acting contraceptive protection

Researchers have developed a new skin patch that uses microneedle technology to deliver a long-acting contraceptive hormone.

14 Jan 2019

Meth’s resurgence spotlights lack of meds to combat the addiction

In 2016, news reports warned the public of an opioid epidemic gripping the nation. But Madeline Vaughn, then a lead clinical intake coordinator at the Houston-based addiction treatment organization Council on Recovery, sensed something different was going on with the patients she checked in from the street.

14 Jan 2019

Opiod prescriptions for pet dogs misused by their masters

A new study has shown that Americans are probably increasingly consuming the opioid analgesics that are prescribed for their pet dogs. The research shows that one of the reasons behind rise in the opioid epidemic could be the rise in prescription opioids for dogs.

14 Jan 2019

Researchers repurpose gene-editing tool CRISPR to develop better antibiotics

A University of Wisconsin-Madison researcher and his collaborators at the University of California, San Francisco have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ones.

11 Jan 2019

New potential immunotherapy target in pancreatic cancer identified

Researchers have identified a new potential immunotherapy target in pancreatic cancer, which so far has been notoriously resistant to treatment with immune checkpoint blockade drugs effective against a variety of other cancers.

11 Jan 2019

New research could have a significant impact on cancer therapy

Research led by Suresh Alahari, PhD, the Fred Brazda Professor of Biochemistry and Molecular Biology at LSU Health New Orleans School of Medicine, has found a new role for a protein discovered by his lab in preventing the growth and spread of breast cancer.

11 Jan 2019

Lupus Research Alliance announces research awards to accelerate development of new therapies

Can "borrowed" drugs for treating other diseases protect the skin in patients with lupus? Can researchers coax the body to weed out harmful immune cells that drive tissue destruction in lupus? Those are just two of the innovative approaches for lupus therapies recognized by the Lupus Research Alliance with the latest round of its Target Identification in Lupus grants.

11 Jan 2019

Review examines what influences HIV-positive patients to stay on antiretroviral drugs in Africa

An international team of researchers have carried out a review of the evidence examining what influences people who are HIV positive to go to health services and then stay on antiretroviral drugs in Africa.

11 Jan 2019

New class of sleeping pill preserves ability to wake in response to danger signals

In a trial of one of the main class of prescription sleeping pills, half the participants slept through a fire alarm as loud as someone vacuuming next to their bed. But a newer alternative preserves the ability to wake in response to danger signals, according to a new research.

11 Jan 2019