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New editorial proposes changes to improve minority representation in clinical trials

In an editorial published in CNS Spectrums, Jay Avasarala, MD, PhD, takes the research community to task for its lack of minority representation in Phase III clinical trials for drugs to treat Multiple Sclerosis (MS).

2 Jan 2019

Study uncovers how tumors backfire on neoadjuvant chemotherapy

Some patients with breast cancer receive chemotherapy before the tumor is removed with surgery. This approach, called 'neoadjuvant' therapy, helps to reduce the size of the tumor to facilitate breast-conserving surgery, and can even eradicate the tumor, leaving few or no cancerous cells for the surgeon to remove.

2 Jan 2019

Novel sensor monitors beating heart cells with minimal disruption

For the first time, engineers have demonstrated an electronic device to closely monitor beating heart cells without affecting their behavior. A collaboration between the University of Tokyo, Tokyo Women's Medical University and RIKEN in Japan produced a functional sample of heart cells with a soft nanomesh sensor in direct contact with the tissue.

2 Jan 2019

New research could help restore youthful characteristics

If only we could keep our bodies young, healthy and energetic, even as we attain the wisdom of our years. New research at the Weizmann Institute of Science suggests this dream could be at least partly obtainable in the future.

2 Jan 2019

Study reveals increase in potency and price of cannabis across Europe

Cannabis resin and herbal cannabis have significantly increased in potency and in price, according to the first study to investigate changes in cannabis across Europe.

2 Jan 2019

Almost 9000 children and teens died from opioid poisonings in over two decades, finds study

Nearly 9,000 children and adolescents died from opioid poisonings with prescription and illicit drugs between 1999 and 2016 based on an analysis of national data.

31 Dec 2018

Insured but still in debt: 5 jobs pulling in $100k a year no match for medical bills

Robert and Tiffany Cano of San Tan Valley, Ariz., have a new marriage, a new house and a 10-month-old son, Brody, who is delighted by his ability to blow raspberries.

28 Dec 2018

Review of recent advances in label-free quantification in cancer proteomics

In recent years, proteomics research has become a popular method for characterizing the functional proteins driving the transformation of malignancy, tracing the large-scale protein alterations induced by anti-cancer drug, as well as discovering the innovative targets and first-in-class drugs for oncologic disorders.

28 Dec 2018

Irish soil contains bacterial strains effective against antibiotic-resistant superbugs

Researchers analyzing soil from Ireland long thought to have medicinal properties have discovered that it contains a previously unknown strain of bacteria which is effective against four of the top six superbugs that are resistant to antibiotics, including MRSA.

27 Dec 2018

New review focuses on the structure-activity relationships of flavonoids

ABCB1 in the ABC transporter family also termed as P-glycoprotein, grants the simultaneous resistance of metastatic cancer cells towards various anti-cancer drugs with different targets and diverse chemical structures.

27 Dec 2018

Targeting thymidylate biosynthesis in kinetoplastid and apicomplexan protozoans

Kinetoplastid and apicomplexan parasites include protozoans which are responsible for human diseases, and cause a serious impact on human health and the socioeconomic growth of developing countries. Chemotherapy is the main option to control these pathogenic organisms.

27 Dec 2018

Scientists suggest need for new approach to confront side effects of common anti-cancer therapy

Results of a new study by neuroscientists at the University of Massachusetts Amherst and the University of Toronto suggest that a new treatment approach is needed - and how this may be possible - to address adverse effects of aromatase inhibitors, drugs commonly prescribed to both men and women to prevent recurrence of estrogen-positive breast cancer.

27 Dec 2018

Neuronal cell death in Alzheimer's disease may actually not be a bad thing, shows study

For the first time, scientists at the Champalimaud Centre for the Unknown, in Lisbon, Portugal, have shown that neuronal cell death in Alzheimer's disease may actually not be a bad thing - on the contrary, it may be the result of a cell quality control mechanism trying to protect the brain from the accumulation of malfunctioning neurons.

27 Dec 2018

Breast cancer drugs could tackle lung cancers resistant to targeted therapies

A class of drugs used to treat certain breast cancers could help to tackle lung cancers that have become resistant to targeted therapies, suggests a new study in mice from the Francis Crick Institute and the Institute of Cancer Research.

27 Dec 2018

Study: Reactivation of HIV-infected cells depends on its size and cell cycle

Thanks to the development of antiretroviral drugs, human immunodeficiency virus is considered a manageable chronic disease today.

27 Dec 2018

NIPER researcher presents a review on autophagy in neuronal cells

Autophagy is a cellular degradation process that can cause the death of a cell in certain conditions. Autophagy is necessary to maintain cellular homeostasis by clearing out damaged cellular organelles and proteins through certain pathways.

27 Dec 2018

Lupin partners with Abbvie to develop and commercialize new targeted oncology treatments

Pharma major Lupin Limited and global biopharmaceutical company AbbVie Inc., today announced that AbbVie has licensed Lupin's MALT1 (Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1) inhibitor program.

25 Dec 2018

FDA authorizes marketing of new tool to aid in nutritional management of breast milk

Today, the U.S. Food and Drug Administration permitted marketing of the Miris Human Milk Analyzer, a new diagnostic test to aid healthcare professionals in measuring nutrients in breast milk, including the concentration of fat, carbohydrate, protein, total solids and energy.

24 Dec 2018

CWRU researcher receives nearly $1 million to study drug resistance mechanisms in prostate cancer

Sanjay Gupta, PhD, of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center will receive $962,000 over three years to investigate drug resistance mechanisms in prostate cancer.

24 Dec 2018

Statins reduce the formation of brown adipose tissue

A certain proportion of the adult population has not only white adipose (or fatty) tissue, but also the brown kind. This brown adipose tissue helps to convert sugar and fat into heat. People with brown adipose tissue are better at regulating their body temperature in the winter, and are less likely to suffer from excess weight or diabetes.

21 Dec 2018

Drugs News and Research

New editorial proposes changes to improve minority representation in clinical trials

Study uncovers how tumors backfire on neoadjuvant chemotherapy

Novel sensor monitors beating heart cells with minimal disruption

New research could help restore youthful characteristics

Study reveals increase in potency and price of cannabis across Europe

Almost 9000 children and teens died from opioid poisonings in over two decades, finds study

Insured but still in debt: 5 jobs pulling in $100k a year no match for medical bills

Review of recent advances in label-free quantification in cancer proteomics

Irish soil contains bacterial strains effective against antibiotic-resistant superbugs

New review focuses on the structure-activity relationships of flavonoids

Targeting thymidylate biosynthesis in kinetoplastid and apicomplexan protozoans

Scientists suggest need for new approach to confront side effects of common anti-cancer therapy

Neuronal cell death in Alzheimer's disease may actually not be a bad thing, shows study

Breast cancer drugs could tackle lung cancers resistant to targeted therapies

Study: Reactivation of HIV-infected cells depends on its size and cell cycle

NIPER researcher presents a review on autophagy in neuronal cells

Lupin partners with Abbvie to develop and commercialize new targeted oncology treatments

FDA authorizes marketing of new tool to aid in nutritional management of breast milk

CWRU researcher receives nearly $1 million to study drug resistance mechanisms in prostate cancer

Statins reduce the formation of brown adipose tissue

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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