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Novel biomaterials approach reveals how mechanical forces shape T cell fate

The successful campaign of adoptive T cell therapies, a type of immunotherapy in which immune T cells are collected from a patient, enhanced outside of the body, and reinfused back into the same patient, especially against blood cancers is well under way.

26 Jun 2023

Beware the chair: sedentary habits harm bones, contribute to higher body fat, study reveals

Researchers compared the associations of sedentary and physical activities with factors such as body fat.

23 Jun 2023

New standard more effective at preventing graft-versus-host disease

Clinicians have a new standard for graft-versus-host disease (GVHD) prevention after allogeneic hematopoietic stem cell transplantation, according to results from a phase III study published June 22 in the New England Journal of Medicine.

22 Jun 2023

World's largest gathering of NF community convenes in Arizona to advance research and care

From June 21 through June 27, the largest gathering of NF researchers, clinicians, and patients in the world will take place at the Fairmont Scottsdale Princess in Scottsdale, Arizona.

22 Jun 2023

MD Anderson and Ochsner Health join forces to advance cancer care in Louisiana

The University of Texas MD Anderson Cancer Center and New Orleans-based Ochsner Health today announced a partnership to create Ochsner MD Anderson Cancer Center in southeastern Louisiana.

22 Jun 2023

Understanding the molecular mechanisms responsible for antimony drug resistance in Leishmania parasites

Leishmaniasis is a tropical disease caused by parasites known as Leishmania, which are transmitted to humans and animals through the bites of more than 90 species of sand flies.

22 Jun 2023

Tranexamic acid use linked to decreased incidence of heterotopic ossification after elbow trauma surgery

For patients undergoing surgery for elbow trauma, treatment with the hemostatic drug tranexamic acid (TXA) is associated with a decreased incidence of heterotopic ossification (HO) – a common complication of abnormal bone formation, reports a study in The Journal of Bone & Joint Surgery.

22 Jun 2023

Uncovering Hidden Diversity in Human Gut Anatomy

In this interview, we spoke to researchers involved in a recent study that found significant variation in the anatomy of human guts.

22 Jun 2023

"All-inside" meniscal repair system provides a high success rate at long-term follow-up

A second-generation "all-inside" meniscal repair system provides a high success rate at long-term follow-up, reports a study in The Journal of Bone & Joint Surgery.

21 Jun 2023

Repurposed drug effective at inhibiting a protein kinase linked to cardiac arrhythmias

Ruxolitinib, a drug that is already approved by the U.S. Food and Drug Administration (FDA) for treating certain cancers and skin conditions, is effective at inhibiting CaMKII, a protein kinase linked to cardiac arrhythmias.

21 Jun 2023

Newborn screening for "bubble-baby" disease boosts survival of children

Screening newborns for severe combined immunodeficiency disease (SCID) significantly increases the survival of children after bone marrow transplantation, a new North American study finds.

21 Jun 2023

Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA, plays an important role in molecular biology.

21 Jun 2023

Newborn screening facilitates early identification of infants with severe combined immunodeficiency

Introducing widespread screening of newborns for a deadly disease called severe combined immunodeficiency, or SCID, followed by early treatment boosted the five-year survival rate of children with the disorder from 73% before the advent of screening to 87% since, researchers report.

20 Jun 2023

UTHSC researchers receive major national award to find new treatments for breast cancer metastasis

UTHSC researchers working to find new treatments to combat breast cancer metastasis recently pulled in a major national award.

20 Jun 2023

Study shows therapeutic potential of HK for treating degenerative rotator cuff injury in humans

The incidence of degenerative rotator cuff injury in the elderly poses a significant economic burden. A novel study by investigators in The American Journal of Pathology, published by Elsevier, has established that mitochondrial sirtuin 3 (SIRT3) activator honokiol (HK) promotes healing of rotator cuff injury in aged mice.

20 Jun 2023

Could mutated blood cells hold the key to lower Alzheimer's risk?

Researchers tested whether clonal hematopoiesis of indeterminate potential (CHIP) status was associated with Alzheimer's disease.

19 Jun 2023

New method can create plant-based meat substitutes with better texture

Sales of plant-based meat products have levelled off in recent years, at least in part because current offerings lack the texture or mouthfeel of a nice T-bone steak or chicken breast.

18 Jun 2023

Social isolation negatively impacts bone health in mice

Social isolation may negatively impact bone health, suggests a study conducted in mice being presented Sunday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

18 Jun 2023

Transgender adolescents rarely chose to discontinue gender-affirming hormone therapy, finds study

A three-year-long retrospective cohort study of a single Atlanta hospital's patient population found transgender and gender-diverse teenagers rarely chose to discontinue gender-affirming hormone therapy, according to a study being presented Sunday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

18 Jun 2023

Testosterone therapy reduces gender dysphoria, depression and suicidality in trans adults

Receiving rapid access to testosterone therapy reduced feelings of gender dysphoria and led to a clinically significant reduction in depression as well as a 50% reduction in suicidality among transgender and gender diverse adults, according to research being presented Sunday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

18 Jun 2023

Bone News and Research

Novel biomaterials approach reveals how mechanical forces shape T cell fate

Beware the chair: sedentary habits harm bones, contribute to higher body fat, study reveals

New standard more effective at preventing graft-versus-host disease

World's largest gathering of NF community convenes in Arizona to advance research and care

MD Anderson and Ochsner Health join forces to advance cancer care in Louisiana

Understanding the molecular mechanisms responsible for antimony drug resistance in Leishmania parasites

Tranexamic acid use linked to decreased incidence of heterotopic ossification after elbow trauma surgery

Uncovering Hidden Diversity in Human Gut Anatomy

"All-inside" meniscal repair system provides a high success rate at long-term follow-up

Repurposed drug effective at inhibiting a protein kinase linked to cardiac arrhythmias

Newborn screening for "bubble-baby" disease boosts survival of children

Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Newborn screening facilitates early identification of infants with severe combined immunodeficiency

UTHSC researchers receive major national award to find new treatments for breast cancer metastasis

Study shows therapeutic potential of HK for treating degenerative rotator cuff injury in humans

Could mutated blood cells hold the key to lower Alzheimer's risk?

New method can create plant-based meat substitutes with better texture

Social isolation negatively impacts bone health in mice

Transgender adolescents rarely chose to discontinue gender-affirming hormone therapy, finds study

Testosterone therapy reduces gender dysphoria, depression and suicidality in trans adults

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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