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Research breaks ground on new ways of treating blood disorders with gene therapy

Research from experts at Michigan Medicine, the Children's Hospital of Philadelphia and Penn Medicine is breaking ground on new ways of treating blood disorders, such as sickle cell anemia, through gene therapy.

9 Aug 2023

Low levels of vitamin K linked to poor lung function

People with low levels of vitamin K in their blood are more likely to have poor lung function and to say they suffer with asthma, chronic obstructive pulmonary disease (COPD) and wheezing, according to a study published today (Thursday) in ERJ Open Research.

9 Aug 2023

Hmga1 protein could be an important therapeutic target for osteoporosis

New research published in The FASEB Journal indicates that increasing the expression of a particular gene may help to prevent bone loss associated with postmenopausal osteoporosis.

9 Aug 2023

Mice lacking TMCO3 gene have shortened bones

Through next-generation sequencing, investigators have identified a mutation in the TMCO3 gene in two sisters with short stature.

9 Aug 2023

Spatially-resolved macrophage phenotyping in liver disease-related research

This review manuscript highlights the relevance of spatially-resolved macrophage phenotyping in liver disease-related research.

8 Aug 2023

Myelodysplastic syndromes are commonly misdiagnosed, study finds

Blood disorders known as myelodysplastic syndromes/neoplasms (MDS) are difficult to diagnose – and are commonly misdiagnosed – putting patients at increased risk for treatment mistakes and other potentially harmful consequences, according to researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations.

8 Aug 2023

Medical grade adhesives for medical device manufacturing

In this interview, Master Bond describes the features and benefits of medical grade adhesives for medical device manufacturing.

From Master Bond Inc. 8 Aug 2023

Amid lack of accountability for bias in maternity care, a California family seeks justice

Aniya was ready to leave. She was dressed in a fuzzy white onesie her mother had packed for her first trip home. Yet Aniya's family had more questions than answers as they cradled the newborn out of the hospital, her mother's body left behind.

8 Aug 2023

Molecular insights: Detecting gene fusions offers new avenues for advanced cancer management

Study identifies gene fusions to understand their relationship with observed pathologies in cancer patients.

8 Aug 2023

Phage therapy shows promise in treating tough Pseudomonas aeruginosa infections

A new international study conducted by the Israeli Phage Therapy Center (IPTC) led by Prof. Ran Nir-Paz at Hadassah Hebrew University Medical Center and Prof. Ronen Hazan of the Faculty of Dental Medicine at The Hebrew University of Jerusalem, using phage PASA16 on compassionate basis to treat tough Pseudomonas aeruginosa infections, has shown promising results with an 86.6% success rate.

7 Aug 2023

Bone mineralization found to dampen metastatic progression of breast cancer

Tumor cells are known to be fickle sleeper agents, often lying dormant in distant tissues for years before reactivating and forming metastasis.

7 Aug 2023

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Researchers investigate whether M2 macrophage-derived exosomes could prevent inflammation-associated damage during sepsis.

7 Aug 2023

New study provides promising results for metformin in periodontitis

Periodontitis, a prevalent global health concern, results in the gradual destruction of tooth-supporting tissues and is often exacerbated by oxidative stress conditions and bacterial changes. Current treatment methodologies include mechanical debridement, anti-inflammatory drugs, and regenerative surgery.

4 Aug 2023

Precocious puberty on the rise in girls during COVID-19 pandemic

The number of girls diagnosed with precocious puberty increased during the COVID-19 pandemic due to potential risk factors such as increased screen time and less physical activity, according to a new study published in the Journal of the Endocrine Society.

3 Aug 2023

Unlocking the potential of Reg3γ: new insights into its metabolic functions and therapeutic prospects

Researchers evaluated the physiological roles of an antimicrobial peptide.

3 Aug 2023

Study finds α5 integrin as a potential therapeutic target in amyotrophic lateral sclerosis

Researchers examined the therapeutic effects of targeting integrins for treating Amyotrophic lateral sclerosis (ALS).

3 Aug 2023

Researchers discover cause of cholesteatomas

Chronic inflammation of the middle ear can cause several problems and complications that can affect a person's hearing and balance.

3 Aug 2023

What are the parallel effects of exercise on cardiometabolic and mental health in children with an excess of adiposity?

Researchers performed a secondary analysis of the ActiveBrains randomized clinical trial (RCT) to look at how a 20-week exercise program affected child health.

2 Aug 2023

Study provides new insights into the intricate cellular processes driving heterotopic ossification

In a new study published on 21 July 2023 by the journal Bone Research, a team of researchers from Johns Hopkins University, using a combination of lineage tracing and single-cell RNA sequencing (scRNA-seq), delved into the contribution of synovial/tendon sheath progenitor cells to heterotopic bone formation.

1 Aug 2023

MGH opens first-of-its-kind center to eliminate lifelong immunosuppression after organ transplant

Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham health system, officially opened the Legorreta Center for Clinical Transplant Tolerance, the first-of-its kind center in the world dedicated to preventing organ rejection after transplant surgery without the use of lifelong immunosuppressive medications.

1 Aug 2023

Bone News and Research

Research breaks ground on new ways of treating blood disorders with gene therapy

Low levels of vitamin K linked to poor lung function

Hmga1 protein could be an important therapeutic target for osteoporosis

Mice lacking TMCO3 gene have shortened bones

Spatially-resolved macrophage phenotyping in liver disease-related research

Myelodysplastic syndromes are commonly misdiagnosed, study finds

Medical grade adhesives for medical device manufacturing

Amid lack of accountability for bias in maternity care, a California family seeks justice

Molecular insights: Detecting gene fusions offers new avenues for advanced cancer management

Phage therapy shows promise in treating tough Pseudomonas aeruginosa infections

Bone mineralization found to dampen metastatic progression of breast cancer

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

New study provides promising results for metformin in periodontitis

Precocious puberty on the rise in girls during COVID-19 pandemic

Unlocking the potential of Reg3γ: new insights into its metabolic functions and therapeutic prospects

Study finds α5 integrin as a potential therapeutic target in amyotrophic lateral sclerosis

Researchers discover cause of cholesteatomas

What are the parallel effects of exercise on cardiometabolic and mental health in children with an excess of adiposity?

Study provides new insights into the intricate cellular processes driving heterotopic ossification

MGH opens first-of-its-kind center to eliminate lifelong immunosuppression after organ transplant

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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