Bone Marrow News and Research

RSS

Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Aggressive cancer stem cells can now be isolated successfully in a scientific breakthrough

University of Texas at Dallas researchers have managed to formulate a new technique by which they can isolate aggressive cells which can be the main cause behind metastasized cancers or cancers that have spread to other major organs from their primary site of occurrence.

22 Feb 2018

Zika virus could be alternative for treatment of aggressive brain cancer

Zika virus, feared for causing microcephaly in babies whose mothers were infected during pregnancy by attacking the cells that will give rise to the fetus's cerebral cortex, could be an alternative for treatment of glioblastoma, the most common and aggressive kind of malignant brain tumor in adults.

21 Feb 2018

Research opens up new avenue to minimize risks of transplants

A bone marrow transplant is often the only therapy available to save leukemia patients, but the risk of complications is high. In spite of devoting considerable time and effort to finding a suitable donor, nearly half of all patients experience an unwanted reaction of their immune system, which often attacks their skin and liver and in up to 50% of cases the intestines.

21 Feb 2018

Scientists show that cutting-edge technique can efficiently sort nano-sized particles

A new cellular messenger discovered by Weill Cornell Medicine scientists may help reveal how cancer cells co-opt the body's intercellular delivery service to spread to new locations in the body.

From Waters | Wyatt Technology 21 Feb 2018

Replenishing a protein could improve healing properties of stem cell therapy after heart attack

Researchers may have found a way to reduce ongoing heart damage that occurs long after a severe heart attack by improving the longevity of stem cells injected into the heart.

13 Feb 2018

Cardiomyocytes fuse transiently during heart development and regeneration

Cardiomyocytes fuse during cardiac development and regeneration. A scientist of the German Centre for Cardiovascular Research (DZHK) discovered these previously unknown processes with the aid of genetically modified zebrafish in which fused cells fluoresce.

9 Feb 2018

Researchers develop safe, potent mRNA vaccine adjuvants that can elicit effective immune response

Production of conventional vaccines, which involves the use of live-attenuated or purified protein subunits of pathogens, is a long and complex process. Nucleic acid vaccines are safer alternatives, and allow easy adjustment of antigen to target specific pathogens.

9 Feb 2018

Moffitt study identifies new drug target that may reduce GVHD risk

Stem cell transplants can cure patients with high-risk leukemia or lymphoma. Graft-versus-host disease is a potentially life-threatening side effect that occurs when the donor's immune cells attack the recipient's normal tissues.

5 Feb 2018

Novel grape-derived compounds could be developed as therapeutic agents for treatment of depression

In a study to be published online February 2 in Nature Communications, scientists from the Icahn School of Medicine at Mount Sinai describe an extensive analysis of novel grape-derived compounds, dihydrocaffeic acid (DHCA) and malvidin-3'-O-glucoside (Mal-gluc),which might be developed as therapeutic agents for the treatment of depression.

2 Feb 2018

Historic study involving Simmons Cancer Center shows effectiveness of CAR-T therapy

A historic study involving researchers from UT Southwestern's Harold C. Simmons Comprehensive Cancer Center demonstrates the effectiveness of CAR-T therapy, which uses genetically modified immune cells to treat acute lymphoblastic leukemia (ALL) in children and young adults. The research appears in the New England Journal of Medicine.

1 Feb 2018

Scientists discover how gene mutation affects T cell function to promote immune disorders

Scientists discovered how a gene mutation affects T cell function to promote immune disorders and then tested a treatment based on the discovery - successfully fixing donated immune cells from a 16-year-old boy with an abnormally low level of white blood cells called lymphopenia.

30 Jan 2018

UAMS Myeloma Institute expert compiles new book on Castleman disease

Castleman disease, a rare disorder of the lymph nodes and related tissues, was identified and named more than a half-century ago but, until recently, no one had written a book exclusively about it.

30 Jan 2018

NYU Langone Health introduces new lung transplant program

The Transplant Institute at NYU Langone Health has launched a new lung transplant program, the third program of its kind in the greater New York City area, expanding regional access to this specialized level of care.

30 Jan 2018

FDA approves new radioactive drug for treatment of rare digestive tract cancers

The U.S. Food and Drug Administration today approved Lutathera (lutetium Lu 177 dotatate) for the treatment of a type of cancer that affects the pancreas or gastrointestinal tract called gastroenteropancreatic neuroendocrine tumors (GEP-NETs).

29 Jan 2018

Microbiome research offers new clues to increased HIV risk in women

Drawing from data collected for years by AIDS researchers in six African nations, scientists have pinpointed seven bacterial species whose presence in high concentrations may significantly increase the risk of HIV infection in women.

27 Jan 2018

Researchers identify promising new drug target for Ewing sarcoma

Screening a class of recently-developed drug compounds -- so-called "CDK inhibitors" capable of blocking CDK7/12/13 proteins -- against hundreds of different human cancer cell lines, researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center have found that CDK12 inhibitors pack a particularly lethal punch to Ewing sarcoma, a rare cancer typically affecting children and young adults.

25 Jan 2018

Phototherapeutic technology shows potential as anti-cancer weapon

A new anti-cancer strategy wields light as a precision weapon. Unlike traditional light therapy - which is limited to the skin and areas accessible with an endoscope - this technique can target and attack cancer cells that have spread deep inside the body, according to researchers at Washington University School of Medicine in St. Louis.

25 Jan 2018

CD34 protein found to be much more than a stem cell marker

A protein used to identify blood-forming cells is much more than a mere surface marker. A KAUST study shows that this protein, known as CD34, also plays a key role in binding adhesion molecules in the bone marrow.

24 Jan 2018

TSRI scientists identify factors crucial to mesenchymal stem cell differentiation

Researchers at The Scripps Research Institute recently published a study in the journal Cell Death and Differentiation identifying factors crucial to mesenchymal stem cell differentiation, providing insight into how these cells should be studied for clinical purposes.

24 Jan 2018

Researchers block common siren call of glioblastoma and metastatic breast cancer

Aggressive cancers like glioblastoma and metastatic breast cancer have in common a siren call that beckons the bone marrow to send along whatever the tumors need to survive and thrive.

23 Jan 2018

Bone Marrow News and Research

Further Reading

Aggressive cancer stem cells can now be isolated successfully in a scientific breakthrough

Zika virus could be alternative for treatment of aggressive brain cancer

Research opens up new avenue to minimize risks of transplants

Scientists show that cutting-edge technique can efficiently sort nano-sized particles

Replenishing a protein could improve healing properties of stem cell therapy after heart attack

Cardiomyocytes fuse transiently during heart development and regeneration

Researchers develop safe, potent mRNA vaccine adjuvants that can elicit effective immune response

Moffitt study identifies new drug target that may reduce GVHD risk

Novel grape-derived compounds could be developed as therapeutic agents for treatment of depression

Historic study involving Simmons Cancer Center shows effectiveness of CAR-T therapy

Scientists discover how gene mutation affects T cell function to promote immune disorders

UAMS Myeloma Institute expert compiles new book on Castleman disease

NYU Langone Health introduces new lung transplant program

FDA approves new radioactive drug for treatment of rare digestive tract cancers

Microbiome research offers new clues to increased HIV risk in women

Researchers identify promising new drug target for Ewing sarcoma

Phototherapeutic technology shows potential as anti-cancer weapon

CD34 protein found to be much more than a stem cell marker

TSRI scientists identify factors crucial to mesenchymal stem cell differentiation

Researchers block common siren call of glioblastoma and metastatic breast cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News