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Tiny light source and sensors in endoscope may detect esophageal cancer more accurately

A tiny light source and sensors at the end of an endoscope may provide a more accurate way to identify pre-cancerous cells in the lining of the esophagus.

4 Jan 2011

Researchers study relationship between MITF, ATF2 in melanoma development

Melanoma is one of the least common types of skin cancer, but it is also the most deadly. Melanocytes (pigment-producing skin cells) lose the genetic regulatory mechanisms that normally limit their number, allowing them to divide and proliferate out of control. One such regulator, called MITF, controls an array of genes that influence melanocyte development, function and survival.

24 Dec 2010

Scientists pinpoint brain site where leptin hormone may trigger onset of puberty

UT Southwestern Medical Center researchers have pinpointed a tiny site in the brain where the hormone leptin may help trigger the onset of puberty.

23 Dec 2010

Arsenic agent for leukemia beneficial in treating medulloblastoma, Ewing's Sarcoma

Researchers at the Georgetown Lombardi Comprehensive Cancer Center, a part of Georgetown University Medical Center, have found that an arsenic-based agent already FDA-approved for a type of leukemia may be helpful in another hard-to-treat cancer, Ewing's Sarcoma (ES). The research, based on animal studies, also suggests the drug might be beneficial in treating medulloblastoma, a highly malignant pediatric brain cancer.

23 Dec 2010

Later onset of puberty associated with malnutrition, earlier onset to childhood obesity

The timing of the onset of puberty is linked to levels of nutrition: later onset is associated with malnutrition, while earlier onset is linked to childhood obesity. A team of researchers, led by Carol Elias, at the University of Texas Southwestern Medical Center, Dallas, has now generated data in mice that run counter to current thinking about the molecular pathway by which nutrition status affects the onset of puberty. Further, the team defines a new regulatory pathway for the process, which, if confirmed in humans, could potentially lead to new approaches to treating disorders of puberty and fertility.

23 Dec 2010

Researchers receive $100,000 NFL grant to study tissue engineering for spinal injuries

Researchers from Cornell University and Weill Cornell Medical College have been awarded $100,000 by NFL Charities, the charitable foundation of the National Football League owners, to research tissue engineering for spinal injuries.

22 Dec 2010

Domainex wins 2010 Genesis Life Science Innovation and Enterprise Programme Of The Year Award

Domainex Ltd, the leading UK-based drug discovery CRO, has won the 2010 Genesis Life Science Innovation and Enterprise Programme Of The Year Award. This Award was made in recognition of Domainex's proactive work on promoting academic-industry collaborations, and was adjudicated by leading representatives of the biotechnology and pharmaceutical industries.

From Domainex 15 Dec 2010

DBS targets same class of neuronal cells that respond to physical exercise and drug Prozac

Shooting steady pulses of electricity through slender electrodes into a brain area that controls complex behaviors has proven to be effective against several therapeutically stubborn neurological and neuropsychiatric disorders. Now, a new study has found that this technique, called deep brain stimulation (DBS), targets the same class of neuronal cells that are known to respond to physical exercise and drugs such as Prozac.

15 Dec 2010

Researchers discover central switch that regulates movement of cancer cells

Researchers at the University of Georgia have discovered a central switch that controls whether cells move or remain stationary. The misregulation of this switch may play a role in the increased movement of tumor cells and in the aggressiveness of tumors themselves.

9 Dec 2010

Experimental flu vaccine triggers immune response, protects against flu

Vaccine production hinges on the availability of hundreds of millions of eggs - and even with the vaccine, flu still claims somewhere around 36,000 lives in the United States during a typical year.

7 Dec 2010

Seasonal light cycles can affect development of babies' specific brain function: Study

The season in which babies are born can have a dramatic and persistent effect on how their biological clocks function.

6 Dec 2010

New clue in leukemia mystery

There is new hope for people with acute myelogenous leukemia (AML), a fast-growing cancer of the blood and bone marrow. Research led by Weill Cornell Medical College and published today in the online edition of the journal Cancer Cell reveals a surprising and unexpected cancer-causing mechanism. The investigators discovered that newly identified mutant enzymes in AML create a chemical poison to cause leukemia. Their findings should prove useful in treating patients by providing a molecular target against which to develop new drugs against one subset of AML as well as other cancers.

2 Dec 2010

Marcus evans Summit highlights potential growth, innovation in drug discovery

Drug discovery scientists need to broaden their approaches to pharmaceutical research and development (R&D) and Medicinal Chemistry, to take advantage of untapped opportunities, says Torsten Hoffmann, Head Discovery Chemistry at F. Hoffmann La Roche, Basel, Switzerland. Chemical Biology allows room for innovation, but is often overlooked by scientists in the industry.

29 Nov 2010

How HIV kills CD4 T cells

Researchers appear to have an explanation for a longstanding question in HIV biology: how it is that the virus kills so many CD4 T cells, despite the fact that most of them appear to be "bystander" cells that are themselves not productively infected. That loss of CD4 T cells marks the progression from HIV infection to full-blown AIDS, explain the researchers who report their findings in studies of human tonsils and spleens in the November 24th issue of Cell, a Cell Press publication.

25 Nov 2010

Researchers identify trigger mechanism for quality control checkpoint in cell division process

Researchers from Huntsman Cancer Institute (HCI) at the University of Utah report that they have identified a previously undiscovered trigger mechanism for a quality control checkpoint at the very end of the cell division process in a paper to be published in the November 29 issue of The Journal of Cell Biology and online today.

23 Nov 2010

Researchers document novel form of splicing in nerve cell cytoplasm

Cells have their own version of the cut-and-paste editing function called splicing. Researchers at the University of Pennsylvania School of Medicine have documented a novel form of splicing in the cytoplasm of a nerve cell, which dictates a special form of a potassium channel protein in the outer membrane.

19 Nov 2010

Scientists uncover minute mechanism of nuclear pore complexes at molecular level

Dr. Joseph Glavy at Stevens Institute of Technology studies the smallest and most basic elements of life. The Assistant Professor of Chemical Biology runs the Glavy Lab, where advanced student scientists study the nuclear pore complexes (NPCs) in cells, observing the minutest mechanisms of life as they unfold during mitosis. The Glavy Lab's formal purpose is to study the NPC at the molecular level in the pursuit of the unknown or unexpected in the well-studied but not always well-understood nuclei of living cells.

17 Nov 2010

Specific brain changes suggest new therapeutic targets for Alzheimer's disease

New studies identify brain changes in people with Alzheimer's disease. The results give researchers a greater understanding of the disease and may help at-risk individuals by improving early detection. New animal research also shows a novel approach to Alzheimer's vaccine design that may avoid dangerous side effects. These new results were reported at Neuroscience 2010, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news on brain science and health.

17 Nov 2010

HCI unveils next-generation technology platform for fraud, waste, and abuse prevention and detection

HealthCare Insight (HCI) today unveiled Nucleus™, a next-generation technology platform for fraud, waste, and abuse prevention and detection, at the Annual Training Conference & Anti-Fraud Expo of the National Healthcare Anti-Fraud Association (NHCAA). The Nucleus application features advanced analytics, comprehensive risk scoring, and a customizable interface to help insurers stop fraud before medical claims are paid.

17 Nov 2010

Alkermes's ALKS 33 drug candidate offers potential treatment for multiple disease indications

Alkermes, Inc. today announced the presentation of promising preclinical results for its proprietary opioid modulator, ALKS 33, showing the drug candidate's potential in multiple disease indications.

17 Nov 2010

Cell Nucleus News and Research

Tiny light source and sensors in endoscope may detect esophageal cancer more accurately

Researchers study relationship between MITF, ATF2 in melanoma development

Scientists pinpoint brain site where leptin hormone may trigger onset of puberty

Arsenic agent for leukemia beneficial in treating medulloblastoma, Ewing's Sarcoma

Later onset of puberty associated with malnutrition, earlier onset to childhood obesity

Researchers receive $100,000 NFL grant to study tissue engineering for spinal injuries

Domainex wins 2010 Genesis Life Science Innovation and Enterprise Programme Of The Year Award

DBS targets same class of neuronal cells that respond to physical exercise and drug Prozac

Researchers discover central switch that regulates movement of cancer cells

Experimental flu vaccine triggers immune response, protects against flu

Seasonal light cycles can affect development of babies' specific brain function: Study

New clue in leukemia mystery

Marcus evans Summit highlights potential growth, innovation in drug discovery

How HIV kills CD4 T cells

Researchers identify trigger mechanism for quality control checkpoint in cell division process

Researchers document novel form of splicing in nerve cell cytoplasm

Scientists uncover minute mechanism of nuclear pore complexes at molecular level

Specific brain changes suggest new therapeutic targets for Alzheimer's disease

HCI unveils next-generation technology platform for fraud, waste, and abuse prevention and detection

Alkermes's ALKS 33 drug candidate offers potential treatment for multiple disease indications

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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