Metastasis News and Research

RSS

Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Researchers discover new anti-thrombotic drug target for developing more protective blood thinners

Blood platelets shore up open wounds and help cuts heal, but they can also cause heart attacks and strokes when a congealed ball of platelets known as a thrombus breaks free from a site of injury and gets lodged in blood vessels that feed oxygen to the brain or heart.

24 May 2017

Study findings could lead to quick and new way for predicting efficacy of cancer treatments

Once hailed as a breakthrough in cancer treatment, immunotherapies are now raising concerns as doctors note new side effects like severe allergic reactions, acute-onset diabetes and heart damage.

23 May 2017

Breast cancer cells undergo stiffening state prior to becoming malignant, study shows

A study published now on Nature Communications shows that breast cancer cells undergo a stiffening state prior to acquiring malignant features and becoming invasive.

16 May 2017

Study reveals how proline metabolism supports breast cancer metastasis

A multinational group of scientists, led by professor Sarah-Maria Fendt, have discovered that breast cancer cells that have invaded other organs rely on a different nutrient metabolism to produce energy than normal cells and non-metastasizing cancer cells.

11 May 2017

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

The low oxygen concentrations that prevail in many tumors enhance their propensity to metastasize to other tissues. Researchers at Ludwig-Maximilians-Universitaet in Munich led by Professor Heiko Hermeking have now uncovered the molecular mechanism that links the two phenomena.

11 May 2017

Research illuminates how primary colorectal tumors contribute to premetastatic 'niche' formation

Primary colorectal tumors secrete VEGF-A, inducing CXCL1 and CXCR2-positive myeloid-derived suppressor cell (MDSC) recruitment at distant sites and establishing niches for future metastases, report Medical University of South Carolina investigators in an article published online ahead of print on April 28, 2017 by Cancer Research.

10 May 2017

Brachytherapy is effective treatment option for penile cancer, study shows

Results from the largest group of men treated for cancer of the penis by a single institution have shown that treatment with brachytherapy (a type of radiotherapy) is a good option that can be used instead of surgery in many cases.

8 May 2017

Scientists identify RIOK1 enzyme as new target for cancer therapy

Dr. Florian Weinberg, from Prof. Dr. Tilman Brummer's research group at the Institute of Molecular Medicine and Cell Research of the University of Freiburg, joined forces with scientists from the Departments of Clinical Pathology and Medicine I of the University Medical Centre Freiburg and the Kinghorn Cancer Centre/Garvan Insitute in Australia in an international team that has identified a new target for cancer therapy.

5 May 2017

New research uncovers role of mysterious molecule in skin cancer

New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) at Lake Nona uncovers the modus operandi of a mysterious molecule called SPRIGHTLY that has been previously implicated in colorectal cancer, breast cancer, and melanoma.

3 May 2017

TSRI study reveals clues to where tumor metastases are born

Scientists at The Scripps Research Institute have discovered why some cancers may reoccur after years in remission.

3 May 2017

Study: New gene editing strategy effectively targets cancer-causing ‘fusion genes’ in mouse models

A novel gene therapy using CRISPR genome editing technology effectively targets cancer-causing "fusion genes" and improves survival in mouse models of aggressive liver and prostate cancers, University of Pittsburgh School of Medicine researchers report in a study published online today in Nature Biotechnology.

2 May 2017

AI key to driving precision medicine in cancer?

It is worth noting that in the U.S. and in many countries, digital pathology is still at a very early stage, compared to many other fields that were digitized 15 or 20 years ago such as radiology. There have been some barriers to the adoption of digital pathology such as regulatory challenges that are only just now being overcome. Recently, the FDA approved the use of whole slide imaging software for primary diagnostics.

27 Apr 2017

New technique can test effectiveness of treatments for breast cancer metastases in bone

A new laboratory technique developed by researchers at Baylor College of Medicine and other institutions can rapidly test the effectiveness of treatments for life-threatening breast cancer metastases in bone. The study appears in Nature Communications.

21 Apr 2017

Researchers identify novel molecular mechanism involved in progression, metastasis of TNBC

University of Tsukuba-led researchers identified a novel molecular mechanism involved in progression and metastasis in the most aggressive form of breast cancer.

21 Apr 2017

IRCM researchers discover how immunotherapy works in some cancer patients

What if our immune system could cure cancer? This logic seems almost too simple to be true, but it forms the basis of an emerging cancer treatment—immunotherapy.

19 Apr 2017

Strawberry extract can inhibit spread of breast cancer cells, mice study shows

A study by European and Latin American researchers has shown that strawberry extract can inhibit the spread of laboratory-grown breast cancer cells, even when they are inoculated in female mice to induce tumours.

19 Apr 2017

FAU researchers discover key factor for early metastases in pancreatic cancer

Pancreatic cancer is one of the most aggressive tumour types because it starts forming metastases early. The cancer itself, however, is usually only discovered late. This leads to a high patient mortality rate. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg have now discovered why pancreatic cancer and other malignant types of tumours can disseminate so rapidly.

18 Apr 2017

Metastasis News and Research

Further Reading