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New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

An international Phase 3 clinical trial found that metastatic colorectal cancer patients with a rare genetic tumor mutation called KRAS G12C experienced superior progression-free survival rates compared to standard of care when offered a combination treatment of KRAS inhibitor sotorasib and monoclonal antibody panitumumab.

27 Oct 2023

Study proposes roadmap to improve migrant and refugee health data collection in Europe

Despite rising global mobility, the state of migrant and refugee health data in European health systems is a concern, a new study shows.

27 Oct 2023

Novel replacement strategy holds promise for the treatment of various genetic disorders

Severe Combined Immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development. SCID can also affect B-cell and natural killer cell function and counts.

27 Oct 2023

Watch: California and feds invest in health care for homeless people

KFF Health News senior correspondent Angela Hart appeared on Spectrum News 1's "Los Angeles Times Today" on Oct. 24 to discuss her coverage of state and federal efforts to expand street medicine — a growing field that focuses on treating homeless people wherever they are, whether indoors or on the streets.

27 Oct 2023

Smaller employers weigh a big-company fix for scarce primary care: Their own clinics

With his company's health costs soaring and his workers struggling with high blood pressure and other medical conditions, Winston Griffin, CEO of Laurel Grocery Co., knew his company had to do something.

27 Oct 2023

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.

26 Oct 2023

Youngest children diagnosed with ADHD just as likely to keep diagnosis as older peers

Children who are the youngest in their class to be identified with ADHD are just as likely to keep the diagnosis as older pupils in their year group, scientists have found.

26 Oct 2023

Is retroelement-based gene editing a safer alternative to CRISPR-Cas approaches?

In a Perspective, Stephen Tang and Samuel Sternberg discuss retroelement-based gene editing as a safer alternative to CRISPR-Cas approaches.

26 Oct 2023

Malaria protein discovery opens new avenues for combating deadly infection

The discovery of a malaria protein that helps the parasite grow inside red blood cells and plays a key regulatory role in the parasite's immune evasion tactics could pave the way for new vaccines or therapeutics to combat the deadly infection.

26 Oct 2023

New study challenges long-held belief about how chemotherapy works

A new study from the University of Wisconsin–Madison suggests that chemotherapy may not be reaching its full potential, in part because researchers and doctors have long misunderstood how some of the most common cancer drugs actually ward off tumors.

26 Oct 2023

Study: Nearly 1.7 million people could be living with dementia in England and Wales by 2040

Up to 1.7 million people could be living with dementia in England and Wales by 2040 – over 40% more than previously forecast – finds a new UCL-led study.

26 Oct 2023

Groundbreaking research advances understanding of how pathogens impact cancer

Viral infections are known to be a central cause of more than 10% of cancers worldwide. University of California researchers may have uncovered one of the key reasons why.

26 Oct 2023

Autistic people less likely to be affected by bystander effect in workplace, study finds

A well-established psychological theory states that most of us are less likely to intervene in a bad situation if other people are present, and this 'bystander effect' also applies to workplace settings.

26 Oct 2023

Endometriosis and irritable bowel syndrome share genetic risk factors, UQ research shows

University of Queensland researchers have shown that endometriosis and irritable bowel syndrome (IBS) share genetic risk factors, explaining why patients with one condition may also have the other.

26 Oct 2023

New nanoparticle-based system developed for comprehensive treatment of rheumatoid arthritis

A team of scientists led by KOO Sagang from the Seoul National University and Center for Nanoparticle Research within the Institue for Basic Science Center (IBS), in collaboration with researchers from Korea Institute of Science and Technology (KIST) and the Seoul National University, developed a new solution for the treatment of rheumatoid arthritis (RA).

26 Oct 2023

Somatic mutations in the skin not responsible for the start or spread of psoriasis

Psoriasis - a chronic skin condition - is not caused or spread by spontaneous genetic mutations in the skin, new research suggests.

26 Oct 2023

Newly identified amino acid may play key role in predicting outcomes and treatment of long COVID

University of Alberta researchers have identified an amino acid that may play a key role in predicting poor clinical outcomes and the treatment of long COVID.

26 Oct 2023

Genomic screening encourages people with hemochromatosis to seek treatment and relevant management

Genomic screening to identify hemochromatosis - a disorder that causes iron levels in the body to rise to dangerous levels - encourages people with the condition to seek treatment and ongoing management, a Geisinger study found.

26 Oct 2023

Treatment in ambulance-based mobile stroke unit increases the likelihood of averting strokes

Receiving a clot-busting drug in an ambulance-based mobile stroke unit (MSU) increases the likelihood of averting strokes and complete recovery compared with standard hospital emergency care, according to researchers at Weill Cornell Medicine, NewYork-Presbyterian, UTHealth Houston, Memorial Hermann-Texas Medical Center and five other medical centers across the United States.

26 Oct 2023

Discovery of protein interaction could lead to new schizophrenia treatments

The discovery of a physical interaction between two proteins in brain cells that can be traced in mice to control of movement, anxiety and memory could one day open the door to development of new schizophrenia treatment strategies, researchers say.

26 Oct 2023

OCT News and Research

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

Study proposes roadmap to improve migrant and refugee health data collection in Europe

Novel replacement strategy holds promise for the treatment of various genetic disorders

Watch: California and feds invest in health care for homeless people

Smaller employers weigh a big-company fix for scarce primary care: Their own clinics

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

Youngest children diagnosed with ADHD just as likely to keep diagnosis as older peers

Is retroelement-based gene editing a safer alternative to CRISPR-Cas approaches?

Malaria protein discovery opens new avenues for combating deadly infection

New study challenges long-held belief about how chemotherapy works

Study: Nearly 1.7 million people could be living with dementia in England and Wales by 2040

Groundbreaking research advances understanding of how pathogens impact cancer

Autistic people less likely to be affected by bystander effect in workplace, study finds

Endometriosis and irritable bowel syndrome share genetic risk factors, UQ research shows

New nanoparticle-based system developed for comprehensive treatment of rheumatoid arthritis

Somatic mutations in the skin not responsible for the start or spread of psoriasis

Newly identified amino acid may play key role in predicting outcomes and treatment of long COVID

Genomic screening encourages people with hemochromatosis to seek treatment and relevant management

Treatment in ambulance-based mobile stroke unit increases the likelihood of averting strokes

Discovery of protein interaction could lead to new schizophrenia treatments

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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