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Study reveals impact of residual inflammatory risk on clinical outcomes after PCI

Patients who have persistently high levels of inflammation following percutaneous coronary intervention for coronary artery disease are significantly more likely to die from any cause or to have a heart attack within a year, according to a study of 7,026 patients published in the European Heart Journal.

19 Nov 2018

New methods for preserving shoulder function, quality of life in breast cancer patients

After a prophylactic double mastectomy in 2015, Tina Harrison discovered that she did, indeed, have breast cancer--it just hadn't been detected.

19 Nov 2018

Scientists equip new virus that kills carcinoma cells with protein

Scientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells that are tricked into shielding the cancer from the immune system.

19 Nov 2018

New strategy to hinder emergence of antimicrobial-resistant pathogens

With many disease-causing bacteria ratcheting up their shields against current drugs, new tactics are vital to protect people from treatment-resistant infections.

17 Nov 2018

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

A majority of the HIV-infected cells that persist in HIV-infected individuals even during suppressive antiretroviral therapy originated from cellular proliferation, not viral replication, according to new research published in Nature Communications.

17 Nov 2018

New model of FSHD could be useful to study effectiveness of experimental therapeutics

Facioscapulohumeral muscular dystrophy is the most prevalent dominantly inherited muscular dystrophy in the world. To date, there are no pharmacologic treatments available for the more than 850,000 people affected worldwide.

17 Nov 2018

New first-line treatment for peripheral T-cell lymphoma approved by FDA

The U.S. Food and Drug Administration today expanded the approved use of Adcetris (brentuximab vedotin) injection in combination with chemotherapy for adult patients with certain types of peripheral T-cell lymphoma.

16 Nov 2018

Gene editing could be used to halt kidney disease in patients with Joubert syndrome

For the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave the way for personalized treatment in the future.

16 Nov 2018

Infant gut microbes altered by mother's obesity may increase risk for future disease

Infant gut microbes altered by their mother's obesity can cause inflammation and other major changes within the baby, increasing the risk of obesity and non-alcoholic fatty liver disease later in life, according to researchers at the University of Colorado Anschutz Medical Campus.

16 Nov 2018

Drug used to treat dizziness may slow down growth of triple-negative breast cancer

Screening Food and Drug Administration approved compounds for their ability to stop cancer growth in the lab led to the finding that the drug flunarizine can slow down the growth of triple-negative breast cancer in an animal model of the disease.

16 Nov 2018

NIH awards over $1.8 million to husband-and-wife doctors to test new breast cancer approach

Husband-and-wife doctors at the University of Virginia Cancer Center have been awarded more than $1.8 million from the National Institutes of Health for their effort to improve radiation therapy and breast surgery for patients with early-stage breast cancer.

16 Nov 2018

Research shows how to achieve improved smoking cessation outcomes within California's Medicaid population

New research shows improved smoking cessation outcomes can be achieved within the Medi-Cal (California's Medicaid program) population by supplementing telephone counseling with access to nicotine-replacement patches and moderate financial incentives that are not contingent on outcomes.

16 Nov 2018

Specific bacterial toxins reduce number of cells suppressing immune response

Staphylococcus aureus bacteria can cause numerous diseases, such as skin infections, pneumonia and blood poisoning.

16 Nov 2018

Non-coding genetic variant plays key role in endothelial function and disease incidence

Atherosclerotic disease, the slow and silent hardening and narrowing of the arteries, is a leading cause of mortality worldwide. It is responsible for more than 15 million deaths each year, including an estimated 610,000 people in the United States.

15 Nov 2018

New approach targets matrix surrounding neurons to protect neurons after stroke

To protect neurons and limit the damage after a stroke, researchers from the CNRS, the University of Caen-Normandie, University Paris-Est Créteil, and the company OTR3 have pursued an innovative path: targeting the matrix that surrounds and supports brain cells.

15 Nov 2018

CRISPR-based tool shown to enhance cell-based immunotherapy

Researchers have developed a CRISPR-based tool called SLICE that can boost the effectiveness of immune cell therapies.

15 Nov 2018

Researchers uncover how insect antibiotic targets Gram-negative bacteria

An antibiotic called thanatin attacks the way the outer membrane of Gram-negative bacteria is built. Researchers at the University of Zurich have now found out that this happens through a previously unknown mechanism. Thanatin, produced naturally by the spined soldier bug, can therefore be used to develop new classes of antibiotics.

15 Nov 2018

Treating children with 'bubble baby disease'

An international study published in the journal Blood by researchers led by Dr. Elie Haddad, a pediatric immunologist and researcher at CHU Sainte-Justine and professor at Université de Montréal, highlights the urgent need to develop better treatment strategies for patients suffering from severe combined immune deficiency.

15 Nov 2018

Inhibition of prostaglandin E2 enhances ability to combat infectious colitis

The treatment of intestinal infections caused by some strains of the bacterium Escherichia coli, present in unsanitized or contaminated foods, may have a new ally.

15 Nov 2018

New edition of Red Journal focuses on roles of imaging in radiation oncology

A new special edition of the International Journal of Radiation Oncology* Biology* Physics focuses on the roles of imaging in radiation oncology. The collection explores topics such as improving accuracy with patient positioning, defining radiation therapy volumes using imaging, imaging of functional biomarkers, the role of imaging in post-treatment care, machine learning and artificial intelligence.

15 Nov 2018

Therapy News and Research

Study reveals impact of residual inflammatory risk on clinical outcomes after PCI

New methods for preserving shoulder function, quality of life in breast cancer patients

Scientists equip new virus that kills carcinoma cells with protein

New strategy to hinder emergence of antimicrobial-resistant pathogens

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

New model of FSHD could be useful to study effectiveness of experimental therapeutics

New first-line treatment for peripheral T-cell lymphoma approved by FDA

Gene editing could be used to halt kidney disease in patients with Joubert syndrome

Infant gut microbes altered by mother's obesity may increase risk for future disease

Drug used to treat dizziness may slow down growth of triple-negative breast cancer

NIH awards over $1.8 million to husband-and-wife doctors to test new breast cancer approach

Research shows how to achieve improved smoking cessation outcomes within California's Medicaid population

Specific bacterial toxins reduce number of cells suppressing immune response

Non-coding genetic variant plays key role in endothelial function and disease incidence

New approach targets matrix surrounding neurons to protect neurons after stroke

CRISPR-based tool shown to enhance cell-based immunotherapy

Researchers uncover how insect antibiotic targets Gram-negative bacteria

Treating children with 'bubble baby disease'

Inhibition of prostaglandin E2 enhances ability to combat infectious colitis

New edition of Red Journal focuses on roles of imaging in radiation oncology

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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