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Novel therapeutic targets based on biology of aging show promise for Alzheimer's disease

A scientific strategy that explores therapeutic targets based on the biology of aging is gaining ground as an effective approach to prevent and treat Alzheimer's disease, according to research published in the December 7, 2018 online issue of Neurology.

10 Dec 2018

UC San Diego professor receives NCI Outstanding Investigator Award for cancer research

The National Cancer Institute has awarded David Cheresh, PhD, Distinguished Professor and vice chair of Pathology at University of California San Diego School of Medicine, with a $4.2 million Outstanding Investigator Award to continue his research into cancer's ability to overcome stress, gain drug resistance and metastasize.

10 Dec 2018

Research advances offer hope for patient-tailored AML treatment

Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia.

10 Dec 2018

International investigators fight against the negative campaign on benzodiazepines

In the current issue of Psychotherapy and Psychosomaticsthere is news about an international group of investigators who felt that benzodiazepines are getting unwarranted bad press, compared to other psychotropic drugs.

9 Dec 2018

Study quantifies links between alcohol, drug use and violent deaths

A group of researchers at the University of São Paulo's Medical School (FM-USP) in Brazil recently published the results of a study on the links between alcohol and drug use and the occurrence of violent deaths.

7 Dec 2018

MIT researchers develop antimicrobial peptides from South American wasp’s venom

The venom of insects such as wasps and bees is full of compounds that can kill bacteria. Unfortunately, many of these compounds are also toxic for humans, making it impossible to use them as antibiotic drugs.

7 Dec 2018

Study: Drug reduces hot flash frequency, improves quality of life in breast cancer survivors

Research led by oncologists Roberto Leon-Ferre, M.D. and Charles Loprinzi, M.D. of Mayo Clinic has found that the drug oxybutynin helps to reduce the frequency and intensity of hot flashes in women who are unable to take hormone replacement therapy, including breast cancer survivors.

7 Dec 2018

High intensity statin treatment and adherence could save more lives

Thousands of heart attacks and deaths from cardiovascular disease could be prevented by patients taking higher doses of statins and taking the drugs as advised by doctors.

7 Dec 2018

Online CBT can help treat gastrointestinal disorders in children

Cognitive behavioral therapy online can be useful in treating gastrointestinal disorders in children when no physical cause can be found. This is the viewpoint of researchers at Karolinska Institutet in Sweden that is described in a new study published in the journal Clinical Gastroenterology and Hepatology.

7 Dec 2018

VCU researchers test vaccine against opioid abuse

Virginia Commonwealth University researchers are testing a vaccine against opioid abuse developed by the Scripps Research Institute in California. The vaccine is meant to block the effects of heroin and fentanyl in patients with opioid use disorder.

7 Dec 2018

Newly developed molecules may provide more reliable relief for people with autoimmune diseases

Living with an autoimmune disease can feel like an insider is attacking your body. An estimated 24 million people in the United States are affected by autoimmune diseases, a group of diseases in which a person's immune system attacks part of the person's own body.

7 Dec 2018

Fractals can help describe how cancer spreads in the body and the right tools to stop it

What can seashells, lightning and the coastline of Britain teach us about new drugs for cancer?

7 Dec 2018

New way of controlling HIV latency to completely eradicate the virus

A new study suggests that a genetic switch that causes latent HIV inside cells to begin to replicate can be manipulated to completely eradicate the virus from the human body. Cells harboring latent HIV are "invisible" to the natural defenses of the immune system.

7 Dec 2018

New diagnostic tools may help identify breast cancer patients who could benefit from targeted therapies

A set of emerging diagnostic tools may help identify breast cancer patients who are most likely to benefit from therapies that target important enzymes fueling a range of subtypes, including BCRA-mutated and triple negative cancers.

7 Dec 2018

Researchers use new methods to optimize treatments for tuberculosis meningitis

Although relatively rare in the United States, and accounting for fewer than 5 percent of tuberculosis cases worldwide, TB of the brain--or tuberculosis meningitis (TBM)--is often deadly, always hard to treat, and a particular threat to young children.

6 Dec 2018

Deprescribing could help manage polypharmacy in older adults

Reducing the number of medications older adults use can have surprising benefits, according to research presented in a new issue of the journal Public Policy & Aging Report from The Gerontological Society of America.

6 Dec 2018

Statins are recommended far too often, study shows

Taking cholesterol-lowering drugs, or statins, as a preventive measure can reduce the risk of cardiovascular disease. A study by the University of Zurich now shows that this measure is recommended too often, as current guidelines fail to take into account the risks of side effects.

6 Dec 2018

Researchers aim to demystify bladder immunity

We know that the bladder is a poorly understood organ, critical for storing metabolic waste. What we don’t know is how this unique environment impacts bladder immunity to common diseases such as urinary tract infections and bladder cancer.

6 Dec 2018

Protecting powerhouse of cells could provide better way to treat acute kidney injury

For the first time, scientists have described the body's natural mechanism for temporarily protecting the powerhouses of kidney cells when injury or disease means they aren't getting enough blood or oxygen.

6 Dec 2018

New immuno-assay can detect small molecules with 50-fold greater sensitivity

As medical science has come to understand that the human body is controlled on the molecular level by various proteins, hormones, drugs, and other substances, technologies have developed to detect levels of these molecules in order to monitor health and diagnose disease.

6 Dec 2018

Drugs News and Research

Novel therapeutic targets based on biology of aging show promise for Alzheimer's disease

UC San Diego professor receives NCI Outstanding Investigator Award for cancer research

Research advances offer hope for patient-tailored AML treatment

International investigators fight against the negative campaign on benzodiazepines

Study quantifies links between alcohol, drug use and violent deaths

MIT researchers develop antimicrobial peptides from South American wasp’s venom

Study: Drug reduces hot flash frequency, improves quality of life in breast cancer survivors

High intensity statin treatment and adherence could save more lives

Online CBT can help treat gastrointestinal disorders in children

VCU researchers test vaccine against opioid abuse

Newly developed molecules may provide more reliable relief for people with autoimmune diseases

Fractals can help describe how cancer spreads in the body and the right tools to stop it

New way of controlling HIV latency to completely eradicate the virus

New diagnostic tools may help identify breast cancer patients who could benefit from targeted therapies

Researchers use new methods to optimize treatments for tuberculosis meningitis

Deprescribing could help manage polypharmacy in older adults

Statins are recommended far too often, study shows

Researchers aim to demystify bladder immunity

Protecting powerhouse of cells could provide better way to treat acute kidney injury

New immuno-assay can detect small molecules with 50-fold greater sensitivity

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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