Inflammation News and Research

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How HIV kills CD4 T cells

Researchers appear to have an explanation for a longstanding question in HIV biology: how it is that the virus kills so many CD4 T cells, despite the fact that most of them appear to be "bystander" cells that are themselves not productively infected. That loss of CD4 T cells marks the progression from HIV infection to full-blown AIDS, explain the researchers who report their findings in studies of human tonsils and spleens in the November 24th issue of Cell, a Cell Press publication.

25 Nov 2010

Scientists reveal long-standing mystery about HIV infection

Scientists at Gladstone Institute of Virology and Immunology have solved a long-standing mystery about HIV infection-namely how HIV promotes the death of CD4 T cells.

25 Nov 2010

Chronic high fat cholesterol diet may lead to Alzheimer's disease

Research from the Laboratory of Psychiatry and Experimental Alzheimers Research at the Medical University Innsbruck (Austria) demonstrated that chronic high fat cholesterol diet in rats exhibited pathologies similar to Alzheimer's disease. The results were published in Molecular Cellular Neuroscience with lead author Dr. Christian Humpel. The study was co-authored by PhD students, Celine Ullrich and Michael Pirchl, from the same Laboratory.

24 Nov 2010

Early urinary protein content test during pregnancy predicts later pre-eclampsia

Research led by the University of Leicester and University Hospitals of Leicester NHS Trust has provided a new advance in predicting a potentially serious pregnancy complication.

24 Nov 2010

Bacterial study confirms TLR2 signaling vital for activating human airway epithelial cells

Researchers from the Boston University School of Medicine (BUSM) have demonstrated that commensal species of the genus Neisseriae are low inducers of human airway epithelial cell responses as compared to the pathogenic species.

24 Nov 2010

The effects of pregnancy on oral health

Even though most people are aware that good oral health is essential for the overall health of both mother and child, misunderstandings about the safety of dental care during pregnancy may cause pregnant women to avoid seeing their dentist. The fact is that dentists can create a treatment plan that is safe, effective, and essential for combating the adverse effects of oral disease during pregnancy.

24 Nov 2010

Early diagnosis and treatment result in positive outcomes for RA patients

Positive outcomes in rheumatoid arthritis (RA) are closely linked to early diagnosis and treatment with disease-modifying antirheumatic drugs (DMARDs). A study by researchers in the Netherlands found that patients who are assessed by rheumatologists soon after RA symptoms appear are more likely to experience less joint destruction and improved chances of DMARD-free disease remission.

23 Nov 2010

Parkinson Society Canada awards Quebec scientists $573,384 for research

Quebec Parkinson researchers receive a record $573,384 in funding from Parkinson Society Canada to increase their efforts to identify the causes of this degenerative brain disease for which there is currently no cure. At a Research Innovation event in Montreal this evening, hosted by Parkinson Society Quebec in partnership with McGill University and the CHUM, 11 Parkinson scientists will be lauded for their efforts in getting closer to a cure.

23 Nov 2010

Researchers investigate ways to counteract unhealthy effects of fat

A fat yet muscular mouse is helping researchers learn whether more muscle improves the cardiovascular health of obese individuals. We are looking for ways to counteract the unhealthy effects of fat, said Dr. David Stepp, vascular biologist at the Medical College of Georgia Vascular Biology Center and co-director of MCG's Diabetes & Obesity Discovery Institute.

23 Nov 2010

Sugar in breast milk promotes colitis in newborn: Study

A sugar found in mouse breast milk promotes the generation of colitis in offspring, according to a study published online on November 22 in the Journal of Experimental Medicine

23 Nov 2010

Harvard researcher to receive 2010 Naomi Berrie Award from Columbia University Medical Center

Columbia University Medical Center will present the 2010 Naomi Berrie Award to a Harvard researcher who has made important advances in understanding the molecular basis for links between obesity, diabetes and heart disease. A promising young investigator at Columbia will also be recognized for her novel investigations regarding the basis for disordered lipid metabolism in diabetes.

20 Nov 2010

High CRP and low protein albumin levels associated with increased risk of death after PEG-operations

The combination of high CRP and low levels of the protein albumin in the blood, is associated with an increased risk of death after a PEG-operation; implantation of a nutritional catheter into the stomach through the abdominal wall. This was shown in a new study from the Swedish medical university Karolinska Institutet, published in the scientific journal Gastrointestinal Endoscopy. Of the PEG patients in the study that showed both current indicators, 20 percent died within 30 days.

20 Nov 2010

Platelet Rich Plasma Therapy reduces pain and improves function in knee osteoarthritis patients

The first American study that positions Platelet Rich Plasma Therapy (PRP) as a viable means in managing knee osteoarthritis, appeared today in the December issue of the American Journal of Physical Medicine & Rehabilitation (AJPMR). The study, authored by Dr. Steven Sampson of the Orthohealing Center in Los Angeles, details the account of 14 patients with primary and secondary knee osteoarthritis receiving three platelet-rich plasma injections in the affected knee at 4-week intervals with one year follow up.

20 Nov 2010

FibroGen to present FG-4592 phase 2a study of patients with stage 3-4 Chronic Kidney Disease and anemia

FibroGen, Inc., today announced that new data from a phase 2a study of patients with stage 3-4 Chronic Kidney Disease and anemia will be presented demonstrating that its first-in-class, investigational oral anemia therapy FG-4592 works differently than erythropoiesis stimulating agents (ESAs) to increase hemoglobin.

19 Nov 2010

DCR to present data on DaVita Cathaway program at ASN Annual Meeting

DaVita Clinical Research, a provider of clinical research and diagnostic laboratory services, announced today that 56 posters and five oral presentations will be presented by the Company's unsurpassed renal experts at the 43rd American Society of Nephrology (ASN) Annual Meeting and Scientific Exposition from November 16 - 21, 2010, at the Colorado Convention Center located in Denver, Colorado.

19 Nov 2010

Study suggests pomegranate juice can ward-off complications in kidney disease patients

Studies in recent years have claimed multiple health benefits of pomegranate juice, including that it is a good source of antioxidants and lowers both cholesterol and blood pressure, especially in diabetic and hypertensive patients.

19 Nov 2010

Spleen cells may do more harm than good at site of spinal cord injury

The spleen, an organ that helps the body fight infections, might also be a source of the cells that end up doing more harm than good at the site of a spinal cord injury, new research suggests.

18 Nov 2010

Gene transfer reduces and stabilizes plaque and decreases inflammation

A plaque-fighting gene - studied in various forms by researchers at the Cedars-Sinai Heart Institute for 18 years - has now been transferred intravenously to lab mice bred to model atherosclerosis (clogged arteries) in humans. Studies show the gene transfer reduced and stabilized plaque and decreased inflammation, key factors in cutting the risk of heart disease.

18 Nov 2010

Idera presents data on TLR7, TLR9 antagonist candidate for hyperlipidemia at American Heart Association

Idera Pharmaceuticals, Inc. announced today that it is presenting preclinical data from a study evaluating the mechanism of action of one of its Toll-like receptor (TLR) 7 and TLR9 antagonist candidates in a model of hyperlipidemia.

18 Nov 2010

FDA grants three years of marketing exclusivity to ISTA's BROMDAY

ISTA Pharmaceuticals, Inc. today announced the U.S. Food and Drug Administration (FDA) has granted the Company three years of marketing exclusivity for BROMDAY (bromfenac ophthalmic solution) 0.09%, as provided under the Drug Price Competition and Patent Term Restoration Act, commonly known as the Hatch-Waxman Act.

18 Nov 2010

Inflammation News and Research

How HIV kills CD4 T cells

Scientists reveal long-standing mystery about HIV infection

Chronic high fat cholesterol diet may lead to Alzheimer's disease

Early urinary protein content test during pregnancy predicts later pre-eclampsia

Bacterial study confirms TLR2 signaling vital for activating human airway epithelial cells

The effects of pregnancy on oral health

Early diagnosis and treatment result in positive outcomes for RA patients

Parkinson Society Canada awards Quebec scientists $573,384 for research

Researchers investigate ways to counteract unhealthy effects of fat

Sugar in breast milk promotes colitis in newborn: Study

Harvard researcher to receive 2010 Naomi Berrie Award from Columbia University Medical Center

High CRP and low protein albumin levels associated with increased risk of death after PEG-operations

Platelet Rich Plasma Therapy reduces pain and improves function in knee osteoarthritis patients

FibroGen to present FG-4592 phase 2a study of patients with stage 3-4 Chronic Kidney Disease and anemia

DCR to present data on DaVita Cathaway program at ASN Annual Meeting

Study suggests pomegranate juice can ward-off complications in kidney disease patients

Spleen cells may do more harm than good at site of spinal cord injury

Gene transfer reduces and stabilizes plaque and decreases inflammation

Idera presents data on TLR7, TLR9 antagonist candidate for hyperlipidemia at American Heart Association

FDA grants three years of marketing exclusivity to ISTA's BROMDAY

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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