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Allen Institute for Cell Science launches first predictive and comprehensive, 3D model of live human cell

The Allen Institute for Cell Science today launched the first predictive and comprehensive, 3D model of a live human cell, the Allen Integrated Cell.

9 May 2018

New microfluidic device captures tumor-specific EVs to guide cancer diagnosis and treatment

Precision cancer treatment relies on obtaining molecular information about the tumor to guide effective treatment decisions.

8 May 2018

Scientists discover how potential new drug targets spinal muscular atrophy

Spinal muscular atrophy (SMA) is a genetic disease that can leave infants with weak muscles and trouble breathing. Many with the disease die before age two. To help these patients, doctors need therapies that target the genetic mutation and stop its progression.

8 May 2018

New drug-based treatment to promote weight loss in young patients with genetic obesity

In a new study researchers from the Institute for Experimental Pediatric Endocrinology of the Charité - Universitätsmedizin Berlin have successfully treat patients whose obesity is caused by a genetic defect.

8 May 2018

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

A new study in Biological Psychiatry reports that dementia-related and psychiatric-related proteins cluster together to form aggregates in the brain, leading to abnormal cell function and behavior.

8 May 2018

Cedars-Sinai study provides new insight into potential negative health effects of air pollution

Prolonged exposure to particulate matter in air pollution in the Los Angeles Basin triggered inflammation and the appearance of cancer-related genes in the brains of rats, a Cedars-Sinai study has found.

8 May 2018

Alnylam achieves delivery of novel siRNAs conjugates to the central nervous system

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that the Company has achieved delivery of novel small interfering RNA conjugates to the central nervous system and is planning to advance a pipeline of investigational RNAi therapeutics into clinical development.

8 May 2018

Study: Coarse particulate matter in air triggers inflammation and cancer biomarkers in rat brains

8 May 2018

Researchers harness the precision of CRISPR to knock out single genes in yeast

Researchers have used CRISPR-Cas9 to develop a technology that can precisely target any gene in the yeast species Saccharomyces cerevisiae.

8 May 2018

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

Not all of your genome needs to be active at any given time. Some regions are prone to hopping around the genome in problematic ways if left unchecked; others code for genes that need to be turned off in certain cells or at certain times.

8 May 2018

Using human induced pluripotent stem cells for therapeutic drug testing

Researchers at Li Ka Shing Faculty of Medicine of The University of Hong Kong have successfully demonstrated the use of human induced pluripotent stem cells from patients' skin cells for therapeutic drug testing.

8 May 2018

Study adds robust evidence to higher prevalence of Alzheimer's among women than men

The APOE gene, the strongest genetic risk factor for Alzheimer's disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer's Center.

8 May 2018

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center.

8 May 2018

New review of infants with congenital hyperinsulinism shows surgery benefits

A review of nearly 500 cases of infants with severe congenital hyperinsulinism who underwent partial or near-total removal of their pancreas for persistent hypoglycemia at Children's Hospital of Philadelphia showed that surgeons can cure virtually all patients with the focal, or localized, form of the rare genetic disease.

7 May 2018

Researchers analyze toxicity, other health risks of electronic tobacco heating system

The project was implemented in accordance with the request of the Government of Russian Federation on the evaluation of non-medicinal nicotine products. The inter-agency research group was based at the Semashko National Scientific Research Institute of Public Health.

7 May 2018

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Erythropoietin helps to protect and repair vulnerable brains though it remains a mystery how the anemia drug does so.

7 May 2018

Women's perceptions of male attractiveness do not vary with hormone levels, shows study

Data from almost 600 participants show that women's perceptions of male attractiveness do not vary according to their hormone levels, in contrast with some previous research.

7 May 2018

Study shows advantages of using decellularized muscle to promote tissue regeneration

A new comparative study showed the advantages of using donor decellularized muscle to promote functional tissue regeneration at the site of bulk skeletal muscle loss due to trauma or surgery.

4 May 2018

UTSW study provides insight into potential new therapeutic approaches for skin diseases

Research at UT Southwestern has shown that targeting metabolism in growing cells holds promise for the treatment of skin diseases like psoriasis that are characterized by skin overgrowth resulting from excess cell division, known as hyperproliferation.

4 May 2018

New studies assess benefits and costs of applying intensive blood pressure targets in clinical practice

Following the landmark SPRINT trial, there is a growing body of evidence for reducing systolic blood pressure targets, resulting in the development of new US guidelines. However, this has led to many questions about the impact of such fundamental changes in blood pressure management, and whether they should be implemented in other constituencies.

4 May 2018

Genetic News and Research

Allen Institute for Cell Science launches first predictive and comprehensive, 3D model of live human cell

New microfluidic device captures tumor-specific EVs to guide cancer diagnosis and treatment

Scientists discover how potential new drug targets spinal muscular atrophy

New drug-based treatment to promote weight loss in young patients with genetic obesity

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

Cedars-Sinai study provides new insight into potential negative health effects of air pollution

Alnylam achieves delivery of novel siRNAs conjugates to the central nervous system

Study: Coarse particulate matter in air triggers inflammation and cancer biomarkers in rat brains

Researchers harness the precision of CRISPR to knock out single genes in yeast

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

Using human induced pluripotent stem cells for therapeutic drug testing

Study adds robust evidence to higher prevalence of Alzheimer's among women than men

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

New review of infants with congenital hyperinsulinism shows surgery benefits

Researchers analyze toxicity, other health risks of electronic tobacco heating system

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Women's perceptions of male attractiveness do not vary with hormone levels, shows study

Study shows advantages of using decellularized muscle to promote tissue regeneration

UTSW study provides insight into potential new therapeutic approaches for skin diseases

New studies assess benefits and costs of applying intensive blood pressure targets in clinical practice

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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