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Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Researchers from Sorbonne Université have been reviewing papers exploring different anti-COVID-19 drugs.

19 Nov 2021

Johns Hopkins scientists create a stunning 3D map of blood vessels and stem cells in mouse skull

Johns Hopkins Medicine scientists have used glowing chemicals and other techniques to create a 3D map of the blood vessels and self-renewing "stem" cells that line and penetrate a mouse skull.

18 Nov 2021

Study analyzes association between obesity and endothelial dysfunction in COVID-19 patients

In COVID-19 patients, obesity is the factor most associated with the development of endothelial dysfunction, a condition in which the blood vessels become unable to contract and relax adequately, increasing the risk of events such as heart attacks, thrombosis (blood clotting), and stroke.

15 Nov 2021

Study analyzes the health effects of a patented DGA compound

A study conducted at the University of Jyväskylä analyzed the health effects of a patented DGA compound and compared them to the effects of exercise.

15 Nov 2021

Inflammatory chemicals involved in fat metabolism play key role in ALS, study shows

A new study using genetically engineered mice and human cell and tissue samples has added to evidence that higher levels of inflammatory chemicals involved in fat metabolism occur in people with amyotrophic lateral sclerosis (ALS), the neuromuscular disorder, also known as Lou Gehrig's disease.

15 Nov 2021

Xanthohumol as a potent pan-inhibitor for various coronaviruses

Researchers from China reported the results of their study aimed at finding an effective Mpro inhibitor since Mpro is the best drug target to fight SARS-CoV-2 infection.

12 Nov 2021

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Researchers at the University of Arizona Health Sciences are closer to developing a safe and effective non-opioid pain reliever after a study showed that a new compound they created reduces the sensation of pain by regulating a biological channel linked to pain.

10 Nov 2021

Inhibiting epigenetic modification could be key to reducing cancer metastasis

Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.

10 Nov 2021

Cell-based viral replication system for screening of SARS-CoV-2 drugs

The current study reports a SARS-CoV-2 replicon system within stable cell lines that can be cultured with ease in a standard biosafety level 2 laboratory.

10 Nov 2021

Birmingham Biotech partners with University of Birmingham to commercialize novel anti-viral nasal spray

Birmingham Biotech Ltd, an innovator in diagnostic tests, protective nasal sprays and mobile medical facilities, and the University of Birmingham have signed a licensing agreement to commercialise a novel anti-viral nasal spray that protects against COVID-19.

9 Nov 2021

Elusive white blood cells play a role in impaired T cell functions and counts in people with HIV

In a groundbreaking study of people living with HIV, University of Alberta researchers found that elusive white blood cells called neutrophils play a role in impaired T cell functions and counts, as well as the associated chronic inflammation that is common with the virus.

9 Nov 2021

Targeting Shp2 in oncological treatments appears to worsen the disease

In recent years, much scientific effort and funding has focused on developing drugs that target an enzyme with the unwieldy name of Src homology 2-containing protein tyrosine phosphatase 2 or more briefly, Shp2.

9 Nov 2021

Fat-secreted molecule may cancel out the effects of common breast cancer treatment

Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study led by researchers from the Johns Hopkins Kimmel Cancer Center.

9 Nov 2021

Intersection of multiple social identities may increase suicide risk for lesbian, gay, and bisexual adults

Suicide risk among lesbian, gay, and bisexual adults varies considerably depending on the intersection between sexual identity and other aspects of identity, such as gender, age, and race/ethnicity, according to a study led by researchers at the National Institute of Mental Health (NIMH), part of the National Institutes of Health.

9 Nov 2021

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

The Institute of Human Virology (IHV) at the University of Maryland School of Medicine and MitoPower LLC were awarded an SBIR (Small Business Innovation Research) grant of up to $6.5 million over five years from the National Institutes of Health's National Institute on Alcohol Abuse and Alcoholism.

9 Nov 2021

COVID-19 drug candidate with wide-ranging antiviral activity

A new study investigated the antiviral activity and mechanism of action of Brilacidin against multiple human coronaviruses.

9 Nov 2021

Hemin as a potential therapy for COVID-19

The current study explores the antiviral activity of HO-1 induced by hemin against SARS-CoV-2 and attempts to describe the mechanism of its anti-viral action.

8 Nov 2021

Pacific oyster shows antiviral activity against human coronavirus HCoV-229E

Not only are Pacific oysters (Crassostrea gigas) a seafood delicacy, but they may also be key for helping scientists figure out how to stop the spread of coronaviruses.

7 Nov 2021

Pacific oyster as a weapon against SARS-CoV-2

According to an article published in the journal Reviews in Medical Virology, the effectiveness of mollusc-derived antiviral agents has been proven in many different laboratory and animal studies, while its efficacy against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has also been proposed by recent in silico studies.

7 Nov 2021

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

A new study describes a new small molecule compound that has shown impressive safety, tolerability, and bioavailability against SARS-CoV-2.

7 Nov 2021

Compound News and Research

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Johns Hopkins scientists create a stunning 3D map of blood vessels and stem cells in mouse skull

Study analyzes association between obesity and endothelial dysfunction in COVID-19 patients

Study analyzes the health effects of a patented DGA compound

Inflammatory chemicals involved in fat metabolism play key role in ALS, study shows

Xanthohumol as a potent pan-inhibitor for various coronaviruses

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Inhibiting epigenetic modification could be key to reducing cancer metastasis

Cell-based viral replication system for screening of SARS-CoV-2 drugs

Birmingham Biotech partners with University of Birmingham to commercialize novel anti-viral nasal spray

Elusive white blood cells play a role in impaired T cell functions and counts in people with HIV

Targeting Shp2 in oncological treatments appears to worsen the disease

Fat-secreted molecule may cancel out the effects of common breast cancer treatment

Intersection of multiple social identities may increase suicide risk for lesbian, gay, and bisexual adults

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

COVID-19 drug candidate with wide-ranging antiviral activity

Hemin as a potential therapy for COVID-19

Pacific oyster shows antiviral activity against human coronavirus HCoV-229E

Pacific oyster as a weapon against SARS-CoV-2

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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