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Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences identified a key mechanism for how antiviral immune responses reprogram liver metabolism. Their recent study, which was published in the renowned scientific journal Immunity, investigated the communication between inflammation and liver metabolism during chronic viral infection.

26 Nov 2019

Discovery enables strategies to be developed for preventing malaria transmission

The bacteria that form the gut microbiota influence important processes of the human body, such as digestion, nutrient absorption, and defense against pathogens. The same type of relationship is present in most animals, including in the Anhopheles darlingi mosquito, the main vector of malaria in Brazil.

22 Nov 2019

New study provides better understanding of blood clot formation in cancer patients

Researchers have identified a potential new signaling pathway that may help further the understanding of blood clot formation in cancer patients and ultimately help prevent this complication from occurring.

22 Nov 2019

Researchers develop breakthrough in marine sponge cell culture

Vertebrate, insect, and plant cell lines are important tools for research in many disciplines, including human health, evolutionary and developmental biology, agriculture and toxicology. Cell lines have been established for many organisms, including freshwater and terrestrial invertebrates.

21 Nov 2019

Researchers elucidate role of inflammation resolution sensor in obesity and heart failure

After heart attack injury, several fatty-acid-derived bioactive molecules -- including one called resolvin D1 -- play an essential signaling role to safely clear inflammation and help repair heart muscle. The mechanism of how this resolution occurs is not well-understood.

20 Nov 2019

UC Davis study identifies mechanism to rapidly repair leaky gut in monkeys with SIV infections

A UC Davis study found that the damaged gut lining (known as leaky gut) in monkeys infected with chronic simian immunodeficiency virus (SIV), an HIV-like virus, was rapidly repaired within five hours of receiving Lactobacillus plantarum bacteria.

19 Nov 2019

New technology may offer alternative means of profiling tissues

Current cancer treatment courses often begin with tissue biopsies. Biopsies, however, which involve the physical resection of a small tissue sample, can lead to localized tissue injury, bleeding, inflammation, and stress, as well as increased risk of metastasis.

19 Nov 2019

Cleveland Clinic receives NIH grant to study link between gut microbes, cardiometabolic diseases

The National Institutes of Health has awarded more than $12 million to Cleveland Clinic researchers to study the critical link between gut microbial pathways and the development of cardiometabolic diseases.

19 Nov 2019

Omega-3 supplement continues to protect heart health without increasing prostate cancer risk

Should you take omega-3 pills? Or try to have two to servings of omega-3 rich fish a week, as the American Heart Association recommends? It may seem a bit murky if you follow headlines about nutrition and health.

17 Nov 2019

Melbourne researchers find how MAIT cells identify and attack foreign invaders

Melbourne researchers have identified what makes a specialized immune cell, known as mucosal-associated invariant T (MAIT), cells boost their numbers and attack foreign invaders at the site of the infection.

15 Nov 2019

Study finds vitamin B12 deficiency in pregnancy may induce obesity

A new study which was presented at the annual conference of Society for Endocrinology reports that vitamin B12 deficiency could disrupt the normal metabolism of fat and could indirectly contribute to weight gain and obesity in pregnancy. This emphasizes the need supplement this vitamin during pregnancy, because obesity in pregnancy is linked to a number of adverse health outcomes over the long term, including diabetes.

12 Nov 2019

Impaired liver function during pregnancy can lead to impaired metabolism and weight gain

Impaired liver function during pregnancy may alter gut bacteria composition and increase the risk of obesity in children, according to results presented at The Society for Endocrinology Annual Conference.

11 Nov 2019

Exercise causes changes to some of the body's metabolites, research finds

New research finds that exercise causes changes to some of the body's metabolites - small molecules the body produces during metabolism.

7 Nov 2019

Findings on gut microbiome's interactions could contribute to new therapies for GI diseases

A study from the Texas A&M College of Veterinary Medicine & Biomedical Sciences offers new insight on how the gut bacteria of dogs interact with a healthy vs. unhealthy GI tract, which could contribute to the development of new therapies for GI diseases in both dogs and humans.

6 Nov 2019

Signs of frailty could be identified through a new assessment

Signs of frailty, and the risks it brings, could be identified in young and old people alike through a new assessment developed in a study led by researchers at the University of Strathclyde.

5 Nov 2019

Humanizing cell cultures

Today we know the function and metabolism of any mammalian cell depends on its environment. Such cells have long been cultured under conditions consisting of a basal medium with added nutritional serum. This, however, is not an accurate replica of the cell’s environment within the human body.

5 Nov 2019

Single vaping episode of cannabis could yield positive results in urine drug tests

In a study of six adults, Johns Hopkins Medicine researchers report evidence that a single vaping episode of cannabis that is similar in chemical composition to that found in legal hemp products could possibly result in positive results on urine drug screening tests commonly used by many employers and criminal justice or school systems.

From Johns Hopkins Medicine 4 Nov 2019

Using wastewater to map global use of illicit drugs

Wastewater-based epidemiology is a rapidly developing scientific discipline with the potential for monitoring close to real-time, population-level trends in illicit drug use.

25 Oct 2019

Researchers identify chemical signatures in blood and urine to measure dietary intake

Researchers at McMaster University have identified several chemical signatures, detectable in blood and urine, that can accurately measure dietary intake, potentially offering a new tool for physicians, dieticians and researchers to assess eating habits, measure the value of fad diets and develop health policies.

25 Oct 2019

Metabolite profiling during diagnosis helps identify poor treatment outcomes in ALL

The survival of patients with pediatric acute lymphoblastic leukemia (ALL) has significantly improved in the last several decades. However, novel strategies to identify cases that are likely to respond poorly to treatment are still needed.

24 Oct 2019

Metabolites News and Research

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Discovery enables strategies to be developed for preventing malaria transmission

New study provides better understanding of blood clot formation in cancer patients

Researchers develop breakthrough in marine sponge cell culture

Researchers elucidate role of inflammation resolution sensor in obesity and heart failure

UC Davis study identifies mechanism to rapidly repair leaky gut in monkeys with SIV infections

New technology may offer alternative means of profiling tissues

Cleveland Clinic receives NIH grant to study link between gut microbes, cardiometabolic diseases

Omega-3 supplement continues to protect heart health without increasing prostate cancer risk

Melbourne researchers find how MAIT cells identify and attack foreign invaders

Study finds vitamin B12 deficiency in pregnancy may induce obesity

Impaired liver function during pregnancy can lead to impaired metabolism and weight gain

Exercise causes changes to some of the body's metabolites, research finds

Findings on gut microbiome's interactions could contribute to new therapies for GI diseases

Signs of frailty could be identified through a new assessment

Humanizing cell cultures

Single vaping episode of cannabis could yield positive results in urine drug tests

Using wastewater to map global use of illicit drugs

Researchers identify chemical signatures in blood and urine to measure dietary intake

Metabolite profiling during diagnosis helps identify poor treatment outcomes in ALL

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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