Microbiology News and Research

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Study identifies the cause and treatment for rare rheumatoid-like autoinflammatory condition

The absence of a protein that activates the body's antiviral defenses can cause a rare rheumatoid-like autoinflammatory condition that is treatable with an FDA-approved class of drugs known as TNF (tumor necrosis factor) inhibitors, a global research team led by Mount Sinai has found.

19 Aug 2021

Researchers identify antibodies that could protect against alphaviruses

Alphaviruses - mosquito-borne viruses that can trigger brain infections and arthritis - may have met their match.

19 Aug 2021

Lessons learnt from the COVID-19 swab crisis could help better prepare for future challenges

A major crisis that accompanied the rise of the pandemic was the lack of availability of the nasopharyngeal swab - necessary for testing for COVID-19, which in turn, was necessary to get a grip on the pandemic. An account of how one group addressed that crisis is published this week Journal of Clinical Microbiology, a journal of the American Society for Microbiology.

19 Aug 2021

Auditory and speech processing occur in parallel in the brain

After years of research, neuroscientists have discovered a new pathway in the human brain that processes the sounds of language.

18 Aug 2021

Researchers receive $26.5 million NIH grant to pursue a new strategy for curing HIV

Over the last 40 years, HIV has shifted from a deadly and mysterious virus to one that can be controlled with daily drugs. But attempts to completely eliminate the virus from the bodies of people living with HIV, curing them for good, have failed.

17 Aug 2021

Delta variant unable to evade antibodies elicited by COVID-19 vaccination, finds study

Despite causing a surge in infections this summer that has resulted in thousands of hospitalizations and deaths, the delta variant of the virus that causes COVID-19 is not particularly good at evading the antibodies generated by vaccination, according to a study by researchers at Washington University School of Medicine in St. Louis.

17 Aug 2021

Dysregulation of innate lymphoid cells drives colon cancer progression and immunotherapy resistance

An immune cell subset called innate lymphoid cells (ILC3s) protects against colorectal cancer, in part by helping to maintain a healthy dialogue between the immune system and gut microbes, according to a new study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. The finding opens the door to new strategies for treating this type of cancer.

17 Aug 2021

Study explores the role of nasal bacteria and provides clues to developing better flu, COVID-19 vaccines

While gut microbiota play a critical role in the induction of adaptive immune responses to influenza virus infection, the role of nasal bacteria in the induction of virus-specific adaptive immunity is less clear.

17 Aug 2021

Hedgehog-signaling inhibitor may shift tumor-associated macrophages back to cancer fighters

A form of cell communication called hedgehog signaling is vital for embryonic development in mammals.

16 Aug 2021

Study identifies mechanism of resistance and presents a much-needed target for advanced leukemias

Too many "exhausted" T cells left in the wake of aggressive chemotherapy regimens for patients with advanced chronic lymphocytic leukemia (CLL) make it more challenging for chimeric antigen receptor (CAR) T cell therapy to do its job.

16 Aug 2021

Quick, inexpensive leptospirosis test strip kit to help lower death and disability risk

The Faculty of Medicine, Chulalongkorn University has brought out a quick, inexpensive, and easy-to-use leptospirosis test strip kit to help lower the risk of disability from internal organ failure and death, with the hopes of distributing them to community hospitals across the country.

14 Aug 2021

L452R mutations may have triggered the emergence of several COVID-19 variants

Most of the recently risen coronavirus variants of interest or concern -- delta, kappa, epsilon, iota and lambda -- are universally carrying a mutation in amino acid L452 of the Spike protein that helps the virus bind to host cells.

13 Aug 2021

Pfizer CEO to public: Just trust us on the covid booster

Pfizer CEO Albert Bourla was confident in June about the ability of his company's vaccine to protect against the highly contagious delta variant, as it marched across the globe and filled U.S. hospitals with patients.

13 Aug 2021

How replication and recombination contribute to emergence of SARS-CoV-2 variants

The coronavirus disease 2019 (COVID-19) pandemic has been caused by the rapid outbreak of a novel coronavirus, namely, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). SARS-CoV-2 was first reported in late December 2019 in Wuhan, China. Since then, the virus has already claimed more than 4.3 million lives worldwide.

13 Aug 2021

Link between high-fat diet, gut microbiota and cardiovascular disease revealed

A high-fat diet disrupts the biology of the gut's inner lining and its microbial communities - and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science.

12 Aug 2021

New genomic and geological mapping tool may help track the deadliest of foodborne pathogens

Among the deadliest of foodborne pathogens, Listeria monocytogenes soon may become easier to track down in food recalls and other investigations, thanks to a new genomic and geological mapping tool created by Cornell University food scientists.

11 Aug 2021

Fine aerosols generated during talking, singing may play a major role in SARS-CoV-2 transmission

The coronavirus disease 2019 (COVID-19) has been thought to spread primarily when an infected person coughs or sneezes, but little is known about its transmissibility through activities such as breathing, talking, and singing.

11 Aug 2021

Microbe transmitted between mosquitoes could be key to controlling malaria

A microbe that is transmitted between male and female mosquitoes but can also block reproduction could be key to controlling malaria by targeting its release into mosquito populations, a study says.

10 Aug 2021

How does the mRNA/lipid nanoparticle platform promote protective adaptive immunity against SARS-CoV-2?

Modified mRNA combined with lipid nanoparticles may be beneficial in boosting adaptive immunity against SARS-CoV-2. Research led by Botond Z. Igyártó from Thomas Jefferson University’s Department of Microbiology and Immunology in Pennsylvania recently found that the lipid nanoparticles induce protective adaptive immune responses with antibody titers against lethal doses of the virus.

5 Aug 2021

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

Researchers in Singapore have discovered that brain cells cannot maintain the cholesterol-rich myelin sheath that protects and insulates neurons in the absence of a protein called TDP-43.

4 Aug 2021

Microbiology News and Research

Study identifies the cause and treatment for rare rheumatoid-like autoinflammatory condition

Researchers identify antibodies that could protect against alphaviruses

Lessons learnt from the COVID-19 swab crisis could help better prepare for future challenges

Auditory and speech processing occur in parallel in the brain

Researchers receive $26.5 million NIH grant to pursue a new strategy for curing HIV

Delta variant unable to evade antibodies elicited by COVID-19 vaccination, finds study

Dysregulation of innate lymphoid cells drives colon cancer progression and immunotherapy resistance

Study explores the role of nasal bacteria and provides clues to developing better flu, COVID-19 vaccines

Hedgehog-signaling inhibitor may shift tumor-associated macrophages back to cancer fighters

Study identifies mechanism of resistance and presents a much-needed target for advanced leukemias

Quick, inexpensive leptospirosis test strip kit to help lower death and disability risk

L452R mutations may have triggered the emergence of several COVID-19 variants

Pfizer CEO to public: Just trust us on the covid booster

How replication and recombination contribute to emergence of SARS-CoV-2 variants

Link between high-fat diet, gut microbiota and cardiovascular disease revealed

New genomic and geological mapping tool may help track the deadliest of foodborne pathogens

Fine aerosols generated during talking, singing may play a major role in SARS-CoV-2 transmission

Microbe transmitted between mosquitoes could be key to controlling malaria

How does the mRNA/lipid nanoparticle platform promote protective adaptive immunity against SARS-CoV-2?

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

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