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Lessons from animal brains can help artificial intelligence to overcome difficult barriers

Artificial intelligence (AI) still has a lot to learn from animal brains, says Cold Spring Harbor Laboratory neuroscientist Anthony Zador. Now, he's hoping that lessons from neuroscience can help the next generation of artificial intelligence overcome some particularly difficult barriers.

22 Aug 2019

Research explains why many psychiatric drugs that work in the lab don’t work in people

Current drug development for neuropsychiatric disorders is in crisis, say experts. More than 90 percent of all drugs that are developed for illnesses like schizophrenia, depression, Alzheimer’s disease (AD), or the brain tumor glioblastoma complete successful trials in mice but then come to a grinding halt in human trials, wasting billions of dollars in drug research. This is partly because of obvious behavioral differences between the two species.

22 Aug 2019

Protein implicated in neuron growth and cell adhesion appears crucial for pain sensitization

Researchers from Japan's Osaka University have made an important leap in our understanding of how chronic pain conditions develop.

20 Aug 2019

Alzheimer's drug reverses brain damage in rats exposed to alcohol during adolescence

A drug used to slow cognitive decline in adults with Alzheimer's disease appears to reverse brain inflammation and neuron damage in rats exposed to alcohol during adolescence.

20 Aug 2019

Protein plays important roles in intracellular membrane trafficking in the brain

Our bodies couldn’t operate without the central nervous system - a complex network that coordinates our actions, reflexes, and sensations. Each neuron in your brain has one long cable that snakes away from the main part of the cell.

20 Aug 2019

UCLA scientists discover new insights that may lead to progress in fighting Alzheimer's disease

More than three decades of research on Alzheimer's disease have not produced any major treatment advances for those with the disorder, according to a UCLA expert who has studied the biochemistry of the brain and Alzheimer's for nearly 30 years.

20 Aug 2019

Northwestern scientists receive $3.1 million grant to investigate drug therapies for ALS

Two Northwestern University scientists have received a $3.1 million grant from the National Institute on Aging to collaborate and investigate drug therapies for amyotrophic lateral sclerosis.

18 Aug 2019

Link between endocannabinoids and exercise could lead to better treatment for depression

Researchers know exercise improves mood for people with depression, but there are still questions about exactly how it makes people feel better.

14 Aug 2019

Alzheimer’s disease risk gene is involved in synaptic transmission

A study published today in the journal Cell Reports sheds new light on how the CD2AP gene may enhance Alzheimer's disease susceptibility.

14 Aug 2019

Bile pigment may play an unexpected role in protecting the brain

In studies in mice, Johns Hopkins Medicine researchers report they have found that bilirubin, a bile pigment most commonly known for yellowing the skin of people with jaundice, may play an unexpected role in protecting brain cells from damage from oxidative stress.

From Johns Hopkins Medicine 13 Aug 2019

Antibody target implicated in neuropsychiatric symptoms of lupus discovered

Researchers have identified a specific target of antibodies that are implicated in the neuropsychiatric symptoms of lupus, according to human research published in JNeurosci.

From Society for Neuroscience 13 Aug 2019

Tissue model of Alzheimer's mimics beta-amyloid's effects on blood-brain barrier

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons. They can also damage the blood-brain barrier — the normally tight border that prevents harmful molecules in the bloodstream from entering the brain.

13 Aug 2019

Engineers develop tissue model that mimics beta-amyloid's effects on blood-brain barrier

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons.

13 Aug 2019

Alzheimer's disease attacks brain regions responsible for wakefulness

Researchers and caregivers have noted that excessive daytime napping can develop long before the memory problems associated with Alzheimer's disease begin to unfold.

13 Aug 2019

Excessive daytime sleeping could be an early sign of Alzheimer’s

Excessive daytime napping often develops long before the memory problems associated with Alzheimer's disease occur. Now, researchers may have found the striking new biological explanation for this phenomenon.

12 Aug 2019

New genomic module facilitates more personalized forms of medicine

Researchers from the HSE Epilepsy Lighthouse Project and FutureNeuro, the SFI Research Centre for Chronic and Rare Neurological Diseases hosted by RCSI, have developed a new genomics module in the Irish National Epilepsy Electronic Patient Record system.

9 Aug 2019

Scientists identify group of proteins for repair of nerve fibers

Scientists at the German Center for Neurodegenerative Diseases have identified a group of proteins that help to regenerate damaged nerve cells. Their findings are reported in the journal Neuron.

7 Aug 2019

Statement related to data inaccuracies with newly approved gene therapy

As a public health agency, we believe that it is critical to facilitate the development of innovative safe and effective medical products, like the cellular and gene therapy products that have shown enormous potential to treat previously untreatable diseases.

7 Aug 2019

Alzheimers may be linked to genes that code formation of contacts between neurons

A team of neurobiologists from Peter the Great St. Petersburg Polytechnic University published an article on their study of the causes of Alzheimer's disease and suggested therapy methods.

2 Aug 2019

First-of-its-kind study in space station seeks to find causes of major diseases

High above the Earth, researchers are conducting a first-of-its-kind study to help patients with Parkinson's disease and multiple sclerosis on the planet below. The International Space Station experiment is looking for what triggers these diseases by studying how nerve and immune brain cells interact.

1 Aug 2019

Neuron News and Research

Lessons from animal brains can help artificial intelligence to overcome difficult barriers

Research explains why many psychiatric drugs that work in the lab don’t work in people

Protein implicated in neuron growth and cell adhesion appears crucial for pain sensitization

Alzheimer's drug reverses brain damage in rats exposed to alcohol during adolescence

Protein plays important roles in intracellular membrane trafficking in the brain

UCLA scientists discover new insights that may lead to progress in fighting Alzheimer's disease

Northwestern scientists receive $3.1 million grant to investigate drug therapies for ALS

Link between endocannabinoids and exercise could lead to better treatment for depression

Alzheimer’s disease risk gene is involved in synaptic transmission

Bile pigment may play an unexpected role in protecting the brain

Antibody target implicated in neuropsychiatric symptoms of lupus discovered

Tissue model of Alzheimer's mimics beta-amyloid's effects on blood-brain barrier

Engineers develop tissue model that mimics beta-amyloid's effects on blood-brain barrier

Alzheimer's disease attacks brain regions responsible for wakefulness

Excessive daytime sleeping could be an early sign of Alzheimer’s

New genomic module facilitates more personalized forms of medicine

Scientists identify group of proteins for repair of nerve fibers

Statement related to data inaccuracies with newly approved gene therapy

Alzheimers may be linked to genes that code formation of contacts between neurons

First-of-its-kind study in space station seeks to find causes of major diseases

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