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Bivalent mRNA booster broadens humoral immunity against SARS-CoV-2 Omicron subvariants

Researchers at Emory University, Stanford University, and the National Institute of Allergy and Infectious Diseases evaluated whether bivalent coronavirus disease 2019 (COVID-19) boosters conferred protection against new Omicron subvariants.

2 Nov 2022

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

New research describes a novel route of prevention, using messenger ribonucleic acid (mRNA) molecules that encode protective antibodies within the recipient.

2 Nov 2022

3D model reveals how cadmium exposure may lead to congenital heart disease

Researchers have developed a three-dimensional model that shows how exposure to cadmium might lead to congenital heart disease.

2 Nov 2022

What is the role of cyclophilin-A in alleviating SARS-CoV-2 infections?

A new study aimed to analyze the molecular interactions between the hCypA protein and the SARS-CoV-2 variants to determine the impact of variants on the blocking and binding potential of the hCypA–S protein complex with the ACE2 receptor.

2 Nov 2022

Protein kinase CK2 controls CD8+ T cell effector and memory functions during Listeria infection

The protein kinase CK2 is involved in a wide range of biological processes and cellular functions, including inflammatory responses and pathologies associated with inflammation.

1 Nov 2022

Researchers fabricate cerebral cortical tissues in 3D and functionally integrate them into a brain lesion in mice

Researchers fabricated cerebral cortical tissues in 3D and functionally integrated them into a brain lesion in mice.

1 Nov 2022

New way of reprogramming immune cells shown to work in melanoma

A new way of reprogramming our immune cells to shrink or kill off cancer cells has been shown to work in the otherwise hard-to-treat and devastating skin cancer, melanoma.

31 Oct 2022

Study reports on a novel property of antibodies, light chain coherence

Researchers investigate whether pairs of unrelated B-cells that have similar heavy chains also have the same light chains.

30 Oct 2022

First anti-SARS Cov2 monoclonal antibody candidate of SpikImm demonstrates excellent tolerance

SPK001, the first anti-SARS Cov2 monoclonal antibody candidate of SpikImm, a French biotechnology company founded by Truffle Capital, originally discovered by the Institut Pasteur's Human Immunology Laboratory, directed by Dr. Hugo Mouquet (Inserm Joint Research Unit), has been tested on three initial cohorts of healthy volunteers, and has demonstrated excellent tolerance, in the context of the Phase 1 clinical study, recently labeled as a "national priority" by CAPNET (National Steering Committee for Therapeutic Trials and other Research on Covid-19).

28 Oct 2022

The impact of seasonal coronavirus immunity on susceptibility to SARS-CoV-2 infection and COVID-19 vaccination

Researchers investigated whether immunity against seasonal human coronavirus spike proteins of HKU1, OC43, NL63, or 229E could protect against SARS-CoV-2 in vitro.

28 Oct 2022

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, an international team of researchers leveraged the human light chain apoferritin protomer-derived MULTI-specific, multi-Affinity antibody (Multabody, MB) platform for the generation of broad and potent SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)-neutralizing antibodies (Abs).

27 Oct 2022

Research opens up new avenues for overcoming treatment resistance in colorectal cancer

Colorectal cancer is one of the most common cancers. Its treatment is mainly based on chemotherapy. However, over time, chemotherapy induces resistance in the majority of patients, who end up being unresponsive to the drugs.

27 Oct 2022

Metabolite product from pomegranate improves the function of immune cells to fight against cancer

As part of an interdisciplinary project of the LOEWE Centre Frankfurt Cancer Institute (FCI), researchers from the Georg-Speyer-Haus in Frankfurt am Main, Germany, and Goethe University Frankfurt have succeeded in identifying a new approach for the therapy of colorectal cancer.

27 Oct 2022

in vitro News and Research

Bivalent mRNA booster broadens humoral immunity against SARS-CoV-2 Omicron subvariants

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

3D model reveals how cadmium exposure may lead to congenital heart disease

What is the role of cyclophilin-A in alleviating SARS-CoV-2 infections?

Protein kinase CK2 controls CD8+ T cell effector and memory functions during Listeria infection

Researchers fabricate cerebral cortical tissues in 3D and functionally integrate them into a brain lesion in mice

New way of reprogramming immune cells shown to work in melanoma

Study reports on a novel property of antibodies, light chain coherence

First anti-SARS Cov2 monoclonal antibody candidate of SpikImm demonstrates excellent tolerance

The impact of seasonal coronavirus immunity on susceptibility to SARS-CoV-2 infection and COVID-19 vaccination

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

Research opens up new avenues for overcoming treatment resistance in colorectal cancer

Metabolite product from pomegranate improves the function of immune cells to fight against cancer

What parents need to know about prenatal tests | BGI Perspectives

Researchers fabricate a non-porous biodegradable vascular graft

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

A review of emerging pediatric respiratory viruses

Is there a difference in the risk of hospital admission between BA.1 and BA.2 cases treated with Sotrovimab?

Engineered particles of purified sand could be a potential cure for obesity

Investigating the evidence of synthetic origins of SARS-CoV-2

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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