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Analysis reveals an increasing trend in incidence of youth-onset type 1 and type 2 diabetes

New findings from researchers at Wake Forest University School of Medicine confirm that the rates of Type 1 and Type 2 diabetes continue to increase in children and young adults. Non-Hispanic Black and Hispanic children and young adults also had higher incidence rates of diabetes.

6 Mar 2023

Study reveals a connection between arthritis flare-ups and periodontitis

Regular visits to the dentist might help keep joint pain at bay, too.

6 Mar 2023

Yale Cancer Center receives funding to increase access to early phase clinical trials

Yale Cancer Center is pleased to announce collaborative funding to support and increase access to early phase clinical trials for patients at community sites for cancer care in Connecticut.

6 Mar 2023

Yale scientists seek to identify optimal sequential treatments for advanced cancer

A team of Yale scientists seeks to determine which treatment sequences produce the best results for people with advanced cancer while examining the cost of these treatments.

6 Mar 2023

High-dose anticoagulation can reduce deaths, intubations in hospitalized COVID-19 patients

High-dose anticoagulation can reduce deaths by 30 percent and intubations by 25 percent in hospitalized COVID-19 patients who are not critically ill when compared to the standard treatment, which is low-dose anticoagulation.

6 Mar 2023

Tumors' response to hormone therapy may be a biomarker for personalization of breast radiotherapy

How estrogen receptor-positive (ER+) breast cancer responds to hormone therapy may hold keys to understanding how it will respond to radiation therapy, and an experimental drug that increases the effectiveness of hormone therapy also overcomes radiation resistance in breast cancer, a study by UT Southwestern Medical Center researchers shows.

6 Mar 2023

Researchers investigate the potential effect of folic acid supplementation on DNA mutation rates

It is well established that folic acid supplementation can significantly reduce the risk of birth defects, including neural tube defects like spina bifida, the most common birth defect of the central nervous system and the second most common of all structural birth defects.

6 Mar 2023

Evaluating how bacterial therapeutics may synergize with existing anti-cancer therapies

It may come as a surprise, but bacteria love to grow inside tumors. It's the environment - tumors are typically acidic, have low amounts of oxygen, and are filled with dead cells, which all facilitate bacterial growth.

6 Mar 2023

Study highlights the need to offer genetic testing as standard of care for people with cerebral palsy

A Geisinger meta-analysis of recent research on the genetics of cerebral palsy (CP) provides evidence that genetic testing should be offered as the standard of care for people with the disorder, similar to current recommendations for individuals with other neurodevelopmental disorders (NDD).

6 Mar 2023

New research pinpoints key culprit behind brain cancer metastasis in children

New research pinpoints a key cause of metastasis from an aggressive form of brain cancer in children and provides a potential new therapy for treating these tumors in the future.

6 Mar 2023

Study identifies genetic variants influencing human fertility

Fertility is influenced by mechanisms that influence both reproductive biology and human behavior, according to the largest study to date identifying genetic determinants of the number of children an individual may have.

6 Mar 2023

Erratic sleep patterns may increase blood pressure among teens who have more abdominal fat

Staying awake later into the night and sleeping in on the weekends are hallmarks of adolescent behavior, however, erratic sleep patterns may have consequences for future heart health by increasing blood pressure among teens who have more abdominal fat, according to new research published today in Hypertension, an American Heart Association journal.

6 Mar 2023

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

MK-0616, an experimental oral proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, met its primary endpoint and substantially reduced levels of low-density lipoprotein (LDL) cholesterol in people with high cholesterol and/or heart disease related to clogged arteries, in a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Non-critically ill hospitalized Covid-19 patients could substantially benefit from a higher dose of blood-thinners

Giving noncritically ill patients hospitalized for COVID-19 a higher dose of blood-thinning medication than usual did not significantly reduce the combined risk of death from any cause, need for treatment in an intensive-care unit, a confirmed blood clot or a stroke at 30 days, according to the results of the FREEDOM-COVID trial presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Addition of sotatercept to existing therapy shows promise for the treatment of pulmonary arterial hypertension

Patients with pulmonary arterial hypertension (PAH), a severe, progressive condition that affects the heart and lungs, who were treated with the novel first-in-class medication sotatercept on top of existing therapy experienced significant improvements in walking distance via a six-minute walking test—the study's primary endpoint and a validated surrogate for functional improvement and reduced symptom burden.

6 Mar 2023

Vigorous exercise does not increase risk of serious cardiac events in people with hypertrophic cardiomyopathy

People with the inherited heart condition hypertrophic cardiomyopathy (HCM) who exercised vigorously did not have an increased incidence of serious cardiac events during three years of follow-up compared with people who exercised moderately or were inactive, according to a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Clinical trial shows safety and immunogenicity of temperature-stable experimental TB vaccine

A clinical trial testing a freeze-dried, temperature-stable experimental tuberculosis (TB) vaccine in healthy adults found that it was safe and stimulated both antibodies and responses from the cellular arm of the immune system.

6 Mar 2023

Researchers show how CBD can reduce seizures in treatment-resistant forms of childhood epilepsy

Researchers at Aston University have contributed to the discovery of a previously unknown way in which cannabidiol (CBD), a non-psychoactive component of cannabis, can reduce seizures in many treatment-resistant forms of childhood epilepsy.

6 Mar 2023

Study: More than 25% of parents misrepresented their children's COVID-19 status

More than 25% of parents surveyed report that they were less than truthful about their children's COVID-19 status or that they didn't follow the disease's preventive guidelines during the pandemic for their offspring, according to a nationwide study led in part by University of Utah scientists.

6 Mar 2023

Proactive case-finding strategies should be expanded for earlier treatment of tuberculosis

From a global perspective, tuberculosis is a common disease. It is often associated with poverty-related living conditions and more common in low-income countries. In Germany, the disease is rare, with 4.7 new cases per 100,000 inhabitants.

6 Mar 2023

Medicine News and Research

Analysis reveals an increasing trend in incidence of youth-onset type 1 and type 2 diabetes

Study reveals a connection between arthritis flare-ups and periodontitis

Yale Cancer Center receives funding to increase access to early phase clinical trials

Yale scientists seek to identify optimal sequential treatments for advanced cancer

High-dose anticoagulation can reduce deaths, intubations in hospitalized COVID-19 patients

Tumors' response to hormone therapy may be a biomarker for personalization of breast radiotherapy

Researchers investigate the potential effect of folic acid supplementation on DNA mutation rates

Evaluating how bacterial therapeutics may synergize with existing anti-cancer therapies

Study highlights the need to offer genetic testing as standard of care for people with cerebral palsy

New research pinpoints key culprit behind brain cancer metastasis in children

Study identifies genetic variants influencing human fertility

Erratic sleep patterns may increase blood pressure among teens who have more abdominal fat

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

Non-critically ill hospitalized Covid-19 patients could substantially benefit from a higher dose of blood-thinners

Addition of sotatercept to existing therapy shows promise for the treatment of pulmonary arterial hypertension

Vigorous exercise does not increase risk of serious cardiac events in people with hypertrophic cardiomyopathy

Clinical trial shows safety and immunogenicity of temperature-stable experimental TB vaccine

Researchers show how CBD can reduce seizures in treatment-resistant forms of childhood epilepsy

Study: More than 25% of parents misrepresented their children's COVID-19 status

Proactive case-finding strategies should be expanded for earlier treatment of tuberculosis

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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