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Asians and Pacific Islanders have the highest levels of iron in their blood

UAB and international scientists studying iron-overload disorders have made the unexpected discovery that Asians and Pacific Islanders have the highest levels of iron in their blood of all racial/ethnic groups who were screened.

27 Apr 2005

Children do well with shorter fast before surgery

Children facing surgery can be made more comfortable with little risk by allowing them to have certain liquids up to two hours before the operation, a new review of recent studies has found.

27 Apr 2005

Risk scores identify young people with hardened arteries

Armed with more knowledge about what cardiovascular disease looks like in people ages 15 to 34, co-authors from the University of Texas Health Science Center, the Southwest Foundation for Biomedical Research and institutions in Delaware, New York, Pennsylvania and Louisiana will report...

27 Apr 2005

National clinical trial examines new option for kidney cancer patients

The trial, which opened last September, offers research subjects who qualify a new, targeted therapy in addition to standard immune therapy. The drug combination is being studied in a national Phase II clinical trial led by OHSU Cancer Institute researcher Christopher Ryan, M.D., through the Southwest Oncology Group, one of the largest clinical trial cooperative groups in the United States.

27 Apr 2005

Hereditary colorectal cancer risk lowered in those without certain gene defect

Families with a certain type of hereditary colorectal cancer have a reduced cancer risk if they do not have a gene defect found in many with this type of cancer risk, according to a study in the April 27 issue of JAMA.

26 Apr 2005

Pulsating ultrasound enhances gene therapy for tumors

High-intensity focused ultrasound emitted in short pulses is a promising, non-invasive procedure for enhancing gene delivery to cancerous cells without destroying healthy tissue, according to a study in the May issue of the journal Radiology.

26 Apr 2005

Elderly lung cancer patients tolerate combined chemotherapy and radiotherapy with no higher risk of death than younger patients

Lung cancer remains the leading cause of cancer deaths in the U.S., with half of those diagnosed at age 70 years or older. About 20 percent of patients with lung cancer will have small cell lung cancer (SCLC). In the past, SCLC progressed rapidly despite initial chemotherapy sensitivity and few patients survive three years.

25 Apr 2005

Patient with rare liver condition second ever to survive liver transplant after pregnancy

For Billi Tierney, 30, National Donate Life Month in April has a profound meaning. The first-time mother of Sycamore, Ill., was awaiting anxiously the arrival of her first baby. But she never thought that complications from her pregnancy were going to lead to a week in coma and the urgent need for a liver transplant. Tierney suffered from acute liver fatty of pregnancy, a rare, but serious condition of pregnancy in which there is an excessive accumulation of fat in the liver or liver cells.

23 Apr 2005

Obesity and insulin resistance fuels cardiovascular risk factors in teens

Obesity and insulin resistance are a menacing tag team that fuels cardiovascular risk factors in teens, according to a study reported in an obesity-themed issue of Circulation: Journal of the American Heart Association.

23 Apr 2005

Health officials urge precautions after confirming year’s first case of hantavirus pulmonary syndrome

The Arizona Department of Health Services is urging the public to take appropriate precautions when living or working in rodent infested areas, following the confirmation of the state’s first case of Hantavirus Pulmonary Syndrome (HPS) in 2005.

23 Apr 2005

Breakthrough technology that identifies molecular markers in early lung cancer

The new technology, created in collaboration with SEQUENOM, developers of genetic analysis products, and Methexis Genomics, uses a DNA analysis technique called methylation profiling to detect cells in the lung that are likely to become cancerous.

23 Apr 2005

Brain system that controls the sleep/wake cycle might also play a role in regulating appetite and metabolism

A new mouse study suggests that a brain system that controls the sleep/wake cycle might also play a role in regulating appetite and metabolism. Mice with a mutation in a gene called "Clock," which helps drive circadian rhythm, ate significantly more and gained more weight.

22 Apr 2005

New strategy to identify differences between non-metastatic and highly metastatic breast cancer cells

Researchers at the University of California, San Diego have used a new strategy to identify differences between non-metastatic and highly metastatic breast cancer cells. The article by Valerie Montel et al., "Expression profiling of primary tumors and matched lymphatic and lung metastases in a xenogeneic breast cancer model," appears in the May 2005 issue of The American Journal of Pathology and is accompanied by a commentary.

22 Apr 2005

Body's 24-hour internal clock linked to obesity and diabetes

Obesity and diabetes in both adults and children are rising at alarming rates and a wide range of culprits -- super-sized food portions, lack of exercise due to television, computers, suburban sprawl and loss of gym classes, high-fat and fast foods, sugar-laden drinks and psychological trauma -- have been blamed.

21 Apr 2005

Genes influence how heart failure patients respond to drugs

Genes dictate the color of our hair and eyes. They factor into whether we get cancer or heart disease. And, scientists increasingly recognize, they also ensure some patients will benefit from a prescription drug, while others develop adverse reactions or simply fail to respond at all.

21 Apr 2005

FDA expert panel to review Abiomed's artificial heart

Abiomed, Inc. today announced that the U.S. Food and Drug Administration (FDA) will convene an expert panel of cardiovascular surgeons and cardiologists to review the groundbreaking technologies and clinical trial data behind the AbioCor artificial heart.

20 Apr 2005

RNA interference permanently silences key breast cancer gene

In laboratory mouse experiments, researchers at The University of Texas M. D. Anderson Cancer Center have developed a way to use RNA interference (RNAi) so that it permanently hampers breast cancer development. The technique permanently silences activated STAT3, a crucial gene found in some human breast tumors, thus reducing the cancer's ability to become invasive.

20 Apr 2005

New gene linked to familial cancer

Scientists have identified a new gene that appears to be linked to a small but significant percentage of familial cancer cases – as well as seemingly randomly occurring malignancies.

20 Apr 2005

Antibiotic treatment does not reduce risk of secondary cardiac events

Taking antibiotics weekly for one year does not reduce the risk of a heart attack or other cardiac event for patients with stable coronary artery disease, according to a study funded by the National Heart, Lung, and Blood Institute of the National Institutes of Health. It is published in the April 21, 2005, edition of the New England Journal of Medicine.

20 Apr 2005

ASTRO public awareness campaign wins award

The American Society for Therapeutic Radiology and Oncology’s public awareness campaign to educate cancer patients on their treatment options has won an Award of Distinction from The Communicator Awards in their 2005 Print Media competition. ASTRO also received Awards of Distinction for its quarterly magazine, ASTROnews, and its Annual Meeting Guide magazine supplement.

20 Apr 2005