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Research reveals immune suppressive role of soluble antibodies in tumor progression

Wistar researchers have found that soluble antibodies promote tumor progression by inducing accumulation of myeloid-derived suppressor cells (MDSCs) in pre-clinical cancer models. Results were published online in Cancer Immunology Research.

13 Apr 2018

Researchers unlock new way to use cell's nanostructures as disease biomarkers

Researchers at the University of Sydney have established a method to identify individual nanoparticles released by human cells, opening the way for them to become diagnostic tools in the early-detection of cancers, dementia and kidney disease.

13 Apr 2018

Overestimation of Ebola virus mutation rates

Scientific evidence at the start of the last major Ebola epidemic in West Africa that suggested the virus would change exceptionally rapidly was probably due to methodological biases.

12 Apr 2018

UCLA scientists identify four subtypes of melanoma with different drug sensitivities

Melanoma, a relatively rare but deadly skin cancer, has been shown to switch differentiation states - that is, to regress to an earlier stage of development - which can lead it to become resistant to treatment.

12 Apr 2018

Research team identifies new mutation behind heart failure in South Asians

An international research team involving Karolinska Institutet has identified a new mutation in South Asians that, in combination with a known mutation in the same gene, increases the risk of cardiomyopathy and heart failure.

12 Apr 2018

Scientists find link between over-accumulation of mitochondrial iron and Huntington's disease

Scientists at the University of Wyoming have found that mice engineered to have Huntington's disease (HD) have an over-accumulation of iron in their mitochondria.

11 Apr 2018

ESMO: New system to rank relevance of treatable cancer genetic mutations needed

ESMO, the leading professional organization for medical oncology, welcomes the latest reports from The Cancer Genome Atla as a major resource for researchers across the world and calls for increased across-the-board commitment to translate these efforts into medical advances for the benefit of cancer patients.

11 Apr 2018

Short international trips can lead to spread of colistin resistance

The emergence of antibiotic resistance among dangerous pathogens is increasingly problematic worldwide. Many strains of infectious bacteria have become multidrug-resistant, and cannot be treated with common antibiotic therapies.

11 Apr 2018

NIH study uncovers genetic basis of 'dripping candle wax' bone disease

Researchers at the National Institutes of Health worked with 15 patients from around the world to uncover a genetic basis of "dripping candle wax" bone disease.

11 Apr 2018

Sweet tooth gene linked to less body fat, research shows

People with a gene variation of FGF21 have a predisposition to less body fat than others, new research conducted at the University of Copenhagen, among others, shows.

11 Apr 2018

Researchers discover how 'junk DNA' plays key role in holding the genome together

Researchers at the University of Michigan Life Sciences Institute and the Howard Hughes Medical Institute have determined how satellite DNA, considered to be "junk DNA," plays a crucial role in holding the genome together.

11 Apr 2018

Research identifies link between rare gene variants and survival after blood and marrow transplant

Blood and marrow transplant, or BMT, is a lifesaving and effective treatment for many patients, but the procedure can cause serious and life-threatening complications.

10 Apr 2018

Scientists find new molecular target to treat idiopathic pulmonary fibrosis

Scientists searching for a therapy to stop the deadly and mostly untreatable lung disease, idiopathic pulmonary fibrosis (IPF), found a new molecular target that slows or stops the illness in preclinical laboratory tests.

10 Apr 2018

New project identifies effective community-based strategies to prevent childhood obesity

To improve success rates and combat continuing disparities in the fight against childhood obesity, the Childhood Obesity Declines Project is taking a systematic approach to studying community-based strategies that have led to declining obesity rates.

10 Apr 2018

New research sheds light on how neurons in the brain communicate with one another

Researchers from the University of Leicester have shed new light on how neurons in the brain communicate with one another. This could potentially help in our understanding of how and why a range of neurodegenerative diseases occur.

10 Apr 2018

Low and high HDL cholesterol linked to higher risk of infectious disease

Most people recognize that there is a relationship between cholesterol levels and risk of heart disease. But new research from Copenhagen University Hospital and University of Copenhagen shows that a certain kind of cholesterol might affect our health differently, that is, through a role in the immune system.

10 Apr 2018

Exercise may be best defense for people with genetic predisposition to heart disease

Exercise may be the best way to keep hearts healthy - and it works even for people with a genetic pre-disposition for heart disease, according to new findings in the American Heart Association's journal, Circulation.

10 Apr 2018

Oxford Gene Technology announces leadership changes

Oxford Gene Technology, The Molecular Genetics Company, has announced that on 1st April 2018 Dr John Anson who has been with the company since 2006 as EVP of R&D took over as CEO from Dr Mike Evans, who has become a non-executive director of OGT’s board.

From Oxford Gene Technology 10 Apr 2018

New technique makes it possible to trace lineage of each cell

Every biology textbook states that cells are life's building blocks. But researchers are only now beginning to understand their diversity. Technologies such as RNA sequencing are revealing which genes are expressed in each individual cell.

9 Apr 2018

Families support groundbreaking research on Charcot-Marie-Tooth disease

Lorena Martin's twin daughters kick butt on the soccer field. Martin is proud of how they hold their own, despite having a rare genetic disease called Charcot-Marie-Tooth (CMT), which has damaged their peripheral nervous system. The girls lack proper control of their hands and feet because their nerves can't send signals properly, so they play using power wheelchairs.

9 Apr 2018

Genetic News and Research

Research reveals immune suppressive role of soluble antibodies in tumor progression

Researchers unlock new way to use cell's nanostructures as disease biomarkers

Overestimation of Ebola virus mutation rates

UCLA scientists identify four subtypes of melanoma with different drug sensitivities

Research team identifies new mutation behind heart failure in South Asians

Scientists find link between over-accumulation of mitochondrial iron and Huntington's disease

ESMO: New system to rank relevance of treatable cancer genetic mutations needed

Short international trips can lead to spread of colistin resistance

NIH study uncovers genetic basis of 'dripping candle wax' bone disease

Sweet tooth gene linked to less body fat, research shows

Researchers discover how 'junk DNA' plays key role in holding the genome together

Research identifies link between rare gene variants and survival after blood and marrow transplant

Scientists find new molecular target to treat idiopathic pulmonary fibrosis

New project identifies effective community-based strategies to prevent childhood obesity

New research sheds light on how neurons in the brain communicate with one another

Low and high HDL cholesterol linked to higher risk of infectious disease

Exercise may be best defense for people with genetic predisposition to heart disease

Oxford Gene Technology announces leadership changes

New technique makes it possible to trace lineage of each cell

Families support groundbreaking research on Charcot-Marie-Tooth disease

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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