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Researchers find new tiny molecule that is capable of killing medulloblastoma

A new study by UT Health San Antonio researchers found that a molecule thousands of times smaller than a gene is able to kill medulloblastoma, the most common childhood brain cancer.

8 Nov 2018

Newer technology with modular dual mobility components lowers risk of dislocation

Hip replacement surgery is highly successful in relieving pain, restoring mobility and improving quality of life. More than 330,000 procedures are performed each year in the United States, and that number is expected to almost double by the year 2030.

8 Nov 2018

Precision medicine: Statistical methods play key role in predicting efficacy of new drugs

The aim of "precision medicine" is to devise individualized treatment strategies and therapies. Statistical methods play an important role in predicting the efficacy of drugs from clinical study data, based on patient characteristics.

8 Nov 2018

Cholesterol-lowering drug reduces chance of having second heart problems or stroke

In a clinical trial involving 18,924 patients from 57 countries who had suffered a recent heart attack or threatened heart attack, researchers at the University of Colorado Anschutz Medical Campus and fellow scientists around the world have found that the cholesterol-lowering drug alirocumab reduced the chance of having additional heart problems or stroke.

8 Nov 2018

Researchers develop technique to disrupt communication between microorganisms

The World Health Organization considers Pseudomonas aeruginosa a germ requiring urgent action to prevent and control its spread. The bacteria can cause a variety of diseases from chronic lung infections to sepsis.

8 Nov 2018

Oral antibiotic shows promise to cure uncomplicated gonorrhea

An investigational oral antibiotic called zoliflodacin was well-tolerated and successfully cured most cases of uncomplicated gonorrhea when tested in a Phase 2 multicenter clinical trial, according to findings published today in the New England Journal of Medicine.

8 Nov 2018

CDK2 protein plays key role in heart damage caused by doxorubicin, finds study

A new study by Washington State University researchers suggests that a protein called CDK2 plays a critical role in heart damage caused by doxorubicin, a commonly used chemotherapy drug.

8 Nov 2018

New open source decision support tool could help clinicians chose chemotherapy drugs

The selection of a first-line chemotherapy drug to treat many types of cancer is often a clear-cut decision governed by standard-of-care protocols, but what drug should be used next if the first one fails?

8 Nov 2018

New study shows promise of innovative strategy against HER2-driven lung cancers

The HER2 gene is a well-known driver of breast cancer, where changes in this gene are found in about 1-in-5 cases of the disease. HER2 also contributes to about 3 percent of lung cancers, representing about 6,500 patients per year.

8 Nov 2018

House Dems in new seats of power will steer health policy, attack drug prices

For the first time since passing the Affordable Care Act, Democrats will soon control the House of Representatives and its powerful health committees. But Republicans' tightened grip on the Senate means those hoping for another round of dramatic, progressive reforms may be disappointed.

7 Nov 2018

New prosthetic hand system restores 'feeling' to a person with upper limb amputation

Arizona State University researcher James Abbas is part of a multi-institutional research team that has developed a new prosthetic hand system with a fully implanted, wirelessly controlled neurostimulator that has restored "feeling" to a person with a hand amputation.

7 Nov 2018

Predictive model could improve sepsis care

Researchers from MIT and Massachusetts General Hospital have developed a predictive model that could guide clinicians in deciding when to give potentially life-saving drugs to patients being treated for sepsis in the emergency room.

7 Nov 2018

Midterm results show health is important to voters but no magic bullet

Health care proved important but apparently not pivotal in the 2018 midterm elections on Tuesday as voters gave Democrats control of the U.S. House, left Republicans in charge in the Senate and appeared to order an expansion of Medicaid in at least three states long controlled by Republicans.

7 Nov 2018

New nano-immunotherapy promotes long-term acceptance of transplanted organs

Researchers at the Mount Sinai School of Medicine have developed a new nanotechnology-based immunotherapy that promotes long-term transplant acceptance in an animal model.

7 Nov 2018

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Melbourne scientists have discovered how tumor development is driven by mutations in the most important gene in preventing cancer, p53.

7 Nov 2018

Cannabinoids hold promise in treating children with epilepsy

In recent years, cannabinoids--the active chemicals in medical marijuana-- have been increasingly touted as a potential treatment for a range of neurological and psychiatric disorders. In a Developmental Medicine & Child Neurology review, investigators compare their efficacy with antiepileptic drugs for children with epilepsy.

7 Nov 2018

Study highlights need for interventions to improve statin use among older adults

In a British Journal of Clinical Pharmacology study of older adults prescribed statins, first-year nonadherence and discontinuation rates were high.

7 Nov 2018

Study examines timing of musculoskeletal adverse events that develop during statin therapy

Statins have been linked with muscle pain and other musculoskeletal adverse events in some patients. A new Pharmacology Research & Perspectives study has examined the timing of MAEs that develop during statin therapy and determined whether concomitant drugs used concurrently with statin therapy shifts the timing of MAEs.

7 Nov 2018

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

A research team led by Dr. Xiang David Li from the Department of Chemistry at The University of Hong Kong, in collaboration with scientists from Tsinghua University in China, The Rockefeller University, and The University of Texas MD Anderson Cancer Center in the United States, developed the first chemical inhibitors against a novel therapeutic target for treatment of acute myeloid leukemia, a fast-growing cancer of bone marrow and blood cells.

7 Nov 2018

Determine goals of healthcare before making healthcare-related choices

What are the goals of healthcare? That very question must be asked more frequently before healthcare-related choices are made.

7 Nov 2018

Drugs News and Research

Researchers find new tiny molecule that is capable of killing medulloblastoma

Newer technology with modular dual mobility components lowers risk of dislocation

Precision medicine: Statistical methods play key role in predicting efficacy of new drugs

Cholesterol-lowering drug reduces chance of having second heart problems or stroke

Researchers develop technique to disrupt communication between microorganisms

Oral antibiotic shows promise to cure uncomplicated gonorrhea

CDK2 protein plays key role in heart damage caused by doxorubicin, finds study

New open source decision support tool could help clinicians chose chemotherapy drugs

New study shows promise of innovative strategy against HER2-driven lung cancers

House Dems in new seats of power will steer health policy, attack drug prices

New prosthetic hand system restores 'feeling' to a person with upper limb amputation

Predictive model could improve sepsis care

Midterm results show health is important to voters but no magic bullet

New nano-immunotherapy promotes long-term acceptance of transplanted organs

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Cannabinoids hold promise in treating children with epilepsy

Study highlights need for interventions to improve statin use among older adults

Study examines timing of musculoskeletal adverse events that develop during statin therapy

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

Determine goals of healthcare before making healthcare-related choices

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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