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Drug derived from the hydrangea root shows promise for autoimmune disorders

A drug derived from the hydrangea root, used for centuries in traditional Chinese medicine, shows promise in treating autoimmune disorders, report researchers from the Program in Cellular and Molecular Medicine and the Immune Disease Institute at Children's Hospital Boston (PCMM/IDI), along with the Harvard School of Dental Medicine.

4 Jun 2009

Discovery of biochemical signals that help immune cells remember how to fight infection

Immunology researchers at UT Southwestern Medical Center have discovered how two biochemical signals play unique roles in promoting the development of a group of immune cells employed as tactical assassins.

28 May 2009

Researchers develop questions to determine risk of HIV/AIDS drug resistance

Researchers from the Makerere University hospital in Uganda, the U.S. and Belgium have developed a formula, based on a set of questions, for determining HIV-positive people's risk of treatment failure and drug resistance, according to a study recently published in the Journal of the International AIDS Society, the New York Times reports.

19 May 2009

Research may lead to improved TB vaccines

A team of Vanderbilt University Medical Center investigators has cracked one of clinical medicine's enduring mysteries - what happened to the tuberculosis vaccine. The once-effective vaccine no longer prevents the bacterial lung infection that kills more than 1.7 million people worldwide each year.

19 May 2009

Chronic infection clearly linked to key immunity protein

The reason deadly infections like human immunodeficiency virus (HIV) and hepatitis C never go away is because these viruses disarm the body's defense system.

15 May 2009

Herpes drug Acyclovir does not reduce risk of HIV transmission, does slow HIV progression, study says

The drug acyclovir, which suppresses herpes simplex virus-2, does not reduce the risk of HIV transmission when taken by HIV-positive people who also have herpes, according to a study conducted by researchers at the University of Washington, United Press International reports.

14 May 2009

IRIN/Plus News examines HIV/AIDS services in Zimbabwe following economic crisis

IRIN/Plus News on Monday examined services for people living with HIV/AIDS in Zimbabwe following an economic crisis in the country.

12 May 2009

Study reveals current multi-component vaccines may need reworking

Current strategies for designing vaccines against HIV and cancers, for instance, may enable some components in multi-component vaccines to cancel the effect of others on the immune system, eliminating their ability to provide protection, according to an article to be published shortly in the Proceedings of the National Academy of Sciences (PNAS).

7 May 2009

Early initiation of antiretroviral therapy improves HIV survival rates, study says

The New York Times on Thursday examined a study that found asymptomatic HIV-positive people who delayed antiretroviral treatment until their disease reached an advanced stage faced higher mortality rates than those who initiated treatment earlier.

30 Apr 2009

If started early, HIV treatment reduces death rates toward background levels in African countries

Mortality rates of people starting HIV treatment in four African countries approach those of the general population over time, provided that treatment is started before the immune system has been severely damaged, according to research published this week in the open-access journal PLoS Medicine.

30 Apr 2009

Early HIV treatment decreases the risk of death

Begin treatment as early as possible: this general common sense rule seems to apply to most diseases except HIV-AIDS, which is only treated once a certain number of immune cells called "CD4+" cells have disappeared.

14 Apr 2009

Early administration of HIV antiretroviral therapy improves survival

The first antiretroviral treatments appeared in 1996. Since then, new and better drugs have been discovered that have almost turned AIDS into a chronic disease.

12 Apr 2009

HIV virus may have become more virulent

Damage to patients' immune systems is happening sooner now than it did at the beginning of the HIV epidemic, suggesting the virus has become more virulent, according to a new study in the May 1, 2009 issue of Clinical Infectious Diseases, now available online.

8 Apr 2009

Intestinal parasites significantly reduce immune response to the cholera toxin

Cholera patients also infected with parasitic intestinal worms have a significantly reduced immune response to the cholera toxin, according to a report published March 31st in the open-access journal PLoS Neglected Tropical Diseases.

30 Mar 2009

AHF delegation meets with WHO and UNAIDS, urges action on access to AIDS treatment, testing and condoms

An international delegation from AIDS Healthcare Foundation (AHF), the largest AIDS group in the US which currently provides medical care to more than 98,000 individuals in 21 countries worldwide in the US, Africa, Latin America/Caribbean and Asia, met today with officials from the World Health Organization (WHO) and the Joint United Nations Programme on HIV/AIDS (UNAIDS) to call for action and partnership to vastly increase global access to HIV/AIDS treatment, testing and condoms.

29 Mar 2009

Combo therapy restores T cell numbers in HIV-infected individuals

White blood cells known as CD4+ T cells are the main target of HIV.

16 Mar 2009

Dendritic cells ensure immune tolerance

One of the most important tasks of the immune system is to identify what is foreign and what is self. If this distinction fails, then the body's own structures will be attacked, the result of which could be an autoimmune disease such as diabetes mellitus type 1 or multiple sclerosis. The only way to protect against these afflictions is to destroy all immune factors that turn against the body's own tissue - in other words: immune tolerance.

16 Mar 2009

Experimental microbicide containing natural compound provides protection in monkeys against simian version of HIV

An experimental microbicide containing a naturally occurring compound provides protection in monkeys against the simian version of HIV by diminishing immune responses to the virus, according to a study published Wednesday in the journal Nature, the Los Angeles Times reports.

5 Mar 2009

Liver transplant recipients with hepatitis B may need lifelong antiviral treatment

Patients who undergo liver transplantation for hepatitis B-related liver damage should receive lifelong antiviral treatment to keep the disease from coming back.

26 Feb 2009

Gene therapy shows potential against HIV

A new UCLA AIDS Institute study has found that gene therapy can be developed as a safe and active technique to combat HIV.

22 Feb 2009