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AAP, ACMG release guidelines on best practices for genetic testing and screening of children

For the first time, the American Academy of Pediatrics (AAP) and the American College of Medical Genetics and Genomics (ACMG) spoke with one voice and released a set of recommendations and guidelines on best practices for genetic testing and screening of children.

5 Mar 2013

$USPSTF posts final recommendation statement on vitamin D supplementation to prevent fractures$

USPSTF posts final recommendation statement on vitamin D supplementation to prevent fractures

The U.S. Preventive Services Task Force (USPSTF) has posted its final recommendation statement on vitamin D and calcium supplementation to prevent fractures in adults.

1 Mar 2013

Newborn screening improves detection of lethal form of congenital adrenal hyperplasia (CAH) in girls as well as boys

Contrary to current belief, routine newborn screening improves the detection of the lethal form of congenital adrenal hyperplasia (CAH) in girls as well as boys, saving lives in both sexes, according to a unique study of CAH during the last 100 years published Online First in The Lancet Diabetes and Endocrinology.

27 Feb 2013

U.N. report examines links between man-made chemicals, health issues

"Man-made chemicals in everyday products are likely to be at least the partial cause of a global surge in birth deformities, hormonal cancers and psychiatric diseases, a U.N.-sponsored research team reported on Tuesday," Reuters reports.

21 Feb 2013

GCP could help lengthen life expectancy of certain prostate cancer patients

A natural, nontoxic product called genistein-combined polysaccharide, or GCP, which is commercially available in health stores, could help lengthen the life expectancy of certain prostate cancer patients, UC Davis researchers have found.

21 Feb 2013

Researchers analyze more than 60 brands of cheese available in supermarkets for pollutants

Researchers at the University of Las Palmas de Gran Canaria (Spain) have analysed more than 60 brands of cheese commonly available in supermarkets. The concentration of organochloride contaminants in the majority of the samples was lower than levels set by European legislation, but in a few cases it was higher.

20 Feb 2013

Study identifies and discusses key factors that lead to obesity in pregnant women

A much neglected part of the obesity epidemic is that it has resulted in more overweight/obese women before and during pregnancy. Their offspring also tend to have higher birth weights and more body fat, and carry an increased risk of obesity and chronic diseases later in life. However, the nutritional factors and mechanisms involved pre and during pregnancy that may influence child obesity remain uncertain.

14 Feb 2013

African-American and Caucasian women absorb, metabolize vitamin D at same rate

African-American women battling vitamin D deficiencies need the same dose as Caucasian women to treat the condition, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

13 Feb 2013

Early detection, treatment needed to reduce risk of death and CVD in older Cushing's disease patients

Even after successful treatment, patients with Cushing's disease who were older when diagnosed or had prolonged exposure to excess cortisol face a greater risk of dying or developing cardiovascular disease, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

13 Feb 2013

High anti-M-llerian hormone levels signal increased likelihood of pregnancy, birth

Women with a high concentration of anti-M-llerian hormone stand a better chance of giving birth after in vitro fertilization, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

13 Feb 2013

Study finds reduced insulin effectiveness, high blood pressure in first-born children

Long a source of sibling rivalry, birth order may raise the risk of first-born children developing diabetes or high blood pressure, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

12 Feb 2013

Identification of progenitors may help treat clinical taste dysfunction

Scientists at the Monell Center have identified the location and certain genetic characteristics of taste stem cells on the tongue. The findings will facilitate techniques to grow and manipulate new functional taste cells for both clinical and research purposes.

4 Feb 2013

Retired Jackson Laboratory scientist wins two major international science awards

Douglas Coleman, Ph.D., a retired Jackson Laboratory scientist whose work established the first clues to a genetic component in obesity, has won two major international science awards: the Frontiers of Knowledge Award in Biomedicine from the BBVA Foundation, based in Bilbao, Spain, and the King Faisal International Prize in Medicine from the Saudi Arabian King Faisal Foundation.

31 Jan 2013

Possible new direction for treatment of metabolic syndrome

Obesity might be a very modern problem, but a team of scientists from Taiwan and China is turning to the age-old principles of traditional Chinese medicine (TCM) to help fight it. Breaking research published in the Journal of Biomolecular Structure and Dynamics indicates a possible new direction for the treatment of metabolic syndrome.

31 Jan 2013

Mice with mitochondrial mutation live longer, have less fat

If findings of a new study in mice are any indication, it might be possible to fine-tune cellular powerhouses called mitochondria, tweaking one aspect to increase insulin sensitivity, reduce body and fat mass, and even extend life. Exploiting this target could one day lead to novel treatments for type 2 diabetes - an endocrine system disease that affects 8 percent of the U.S. population. The research also points to promising new avenues of investigation in the biology of aging.

30 Jan 2013

Early-life exposure to TBT chemical can cause obesity

Exposing pregnant mice to low doses of the chemical tributyltin (TBT) - which was used in marine antifouling paints and is used as an antifungal agent in some paints, certain plastics and a variety of consumer products - can lead to obesity for multiple generations without subsequent exposure, a UC Irvine study has found.

25 Jan 2013

Exposure of human f-tal testicles to bisphenol A reduces testosterone production

Bisphenol A (BPA) is a chemical compound that is included in the composition of plastics and resins. It is used, for example, in the manufacture of food containers such as bottles and babies' feeding bottles. It is also found in the protective films used inside food and drink cans and on till receipts where it used as a discloser. Significant levels of BPA have also been found in human blood, urine, amniotic fluid and placentas.

23 Jan 2013

Miscarriage and molecular signals: an interview with Prof Brosens and Prof Quenby

Miscarriage is defined as the spontaneous loss of pregnancy before the baby reaches viability. Besides the physical trauma, miscarriage causes considerable anxiety, stress, and depression.

17 Jan 2013

People with chronic inflammatory conditions may benefit from mindfulness meditation

People suffering from chronic inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease and asthma - in which psychological stress plays a major role - may benefit from mindfulness meditation techniques, according to a study by University of Wisconsin-Madison neuroscientists with the Center for Investigating Healthy Minds at the Waisman Center.

17 Jan 2013

UCI study identifies transgenerational effects of tributyltin

Exposing pregnant mice to low doses of the chemical tributyltin - which is used in marine hull paint and PVC plastic - can lead to obesity for multiple generations without subsequent exposure, a UC Irvine study has found.

17 Jan 2013

Endocrine News and Research

AAP, ACMG release guidelines on best practices for genetic testing and screening of children

USPSTF posts final recommendation statement on vitamin D supplementation to prevent fractures

Newborn screening improves detection of lethal form of congenital adrenal hyperplasia (CAH) in girls as well as boys

U.N. report examines links between man-made chemicals, health issues

GCP could help lengthen life expectancy of certain prostate cancer patients

Researchers analyze more than 60 brands of cheese available in supermarkets for pollutants

Study identifies and discusses key factors that lead to obesity in pregnant women

African-American and Caucasian women absorb, metabolize vitamin D at same rate

Early detection, treatment needed to reduce risk of death and CVD in older Cushing's disease patients

High anti-M-llerian hormone levels signal increased likelihood of pregnancy, birth

Study finds reduced insulin effectiveness, high blood pressure in first-born children

Identification of progenitors may help treat clinical taste dysfunction

Retired Jackson Laboratory scientist wins two major international science awards

Possible new direction for treatment of metabolic syndrome

Mice with mitochondrial mutation live longer, have less fat

Early-life exposure to TBT chemical can cause obesity

Exposure of human f-tal testicles to bisphenol A reduces testosterone production

Miscarriage and molecular signals: an interview with Prof Brosens and Prof Quenby

People with chronic inflammatory conditions may benefit from mindfulness meditation

UCI study identifies transgenerational effects of tributyltin

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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