High Cholesterol News and Research

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Even moderate exercise helps breast cancer recovery

Australian researchers have found that exercise can offer benefits to women recovering from breast cancer treatment.

8 Feb 2009

Resting pulse predicts heart attacks in women

A simple measurement of resting pulse predicts coronary events in women independently of physical activity and common risk factors, such as smoking and alcohol consumption, finds a study published on bmj.com.

3 Feb 2009

Statins may treat cerebral cavernous malformation

In a finding that could save thousands of lives a year, University of Utah School of Medicine researchers have shown that a blood vessel disorder leading to unpredictable, sometimes fatal, hemorrhagic strokes, seizures, paralysis or other problems is treatable with the same statin drugs that millions of people take to control high cholesterol.

27 Jan 2009

Researchers identify compound that frees trapped cholesterol

Researchers at UT Southwestern Medical Center have identified in mice a compound that liberates cholesterol that has inappropriately accumulated to excessive levels inside cells.

27 Jan 2009

Scientists discover a compound that gets rid of excess cholesterol

New research by scientists in the United States carried out in mice has revealed a compound that releases excessive cholesterol accumulated inside cells.

27 Jan 2009

Inflammation worsens danger due to atherosclerosis

Current research suggests that inflammation increases the risk of plaque rupture in atherosclerosis.

23 Jan 2009

Athletes aren't necessarily off the hook when it comes to health risks

College-age football players who gain weight to add power to their blocks and tackles might also be setting themselves up for diabetes and heart disease later in life, a new study suggests.

13 Jan 2009

Innovative brain-scan technology helps visualize brain aging before symptoms appear

UCLA scientists have used innovative brain-scan technology developed at UCLA, along with patient-specific information on Alzheimer's disease risk, to help diagnose brain aging, often before symptoms appear.

6 Jan 2009

Two common biomarkers help predict stroke risk

Two common biomarkers have now been shown to improve the ability to predict who will suffer from a stroke.

18 Dec 2008

Patients with skin disease psoriasis need evaluation of coronary artery disease risk

According to new recommendations in the December 10 issue of The American Journal of Cardiology (AJC), published by Elsevier, new research is called for and patients with severe forms of the skin disease psoriasis should receive evaluation and possible treatment to reduce their risk of coronary artery disease (CAD).

18 Dec 2008

Drug eluting stents provide better outcomes that bare metal stents in angioplasty

Patients receiving drug eluting stents (DES) - stents coated with medication to prevent narrowing of the artery - as part of an angioplasty had better outcomes one year later than patients with bare metal stents, according to a new study to be published in CMAJ.

18 Dec 2008

Single letter in the human genome points to risk for high cholesterol

Write out every letter in the human genome, one A, C, T or G per millimeter, and the text would be 1,800 miles long, roughly the distance from New York to Colorado.

16 Dec 2008

Hospitals using quality improvement program increase compliance to stroke treatment guidelines

Hospitals participating in a voluntary quality improvement program for stroke treatment increased adherence to national recommendations, researchers reported in Circulation: Journal of the American Heart Association.

15 Dec 2008

Psoriasis sufferers more likely to have higher levels of leptin

Patients with the skin disease psoriasis appear more likely to have higher levels of leptin (a hormone produced by fat cells that may contribute to obesity and other metabolic abnormalities) than persons without psoriasis, according to a report in the December issue of Archives of Dermatology.

15 Dec 2008

Nuts and Mediterranean diet appear to help metabolic syndrome

A traditional Mediterranean diet with an additional daily serving of mixed nuts appears to be useful for managing some metabolic abnormalities in older adults at high risk for heart disease, according to a report in the December 8/22 issue of Archives of Internal Medicine.

8 Dec 2008

Scientists find 12 new genes with potential as drug targets

Scientists have identified 12 new genes that are somewhat strange bedfellows: Some link gallstones and blood cholesterol levels, others link melatonin and sleep patterns to small increases in glucose levels and larger jumps in the risk of diabetes.

8 Dec 2008

Coronary CTA is a low cost, non-invasive alternative for evaluating coronary artery disease

Coronary CTA offers a low cost, non-invasive alternative to conventional angiography for evaluating patients who are suspected of having coronary artery disease; true even if the patients have calcified coronary artery plaques, according to a study performed at the Thomas Jefferson University Hospital, Philadelphia, PA.

1 Dec 2008

Presence of gum disease may help dentists and physicians identify risk of cardiovascular disease

Individuals reporting a history of periodontal disease were more likely to have increased levels of inflammation, a risk factor for heart disease, compared to those who reported no history of periodontal disease, according to an American Journal of Cardiology report available online today.

25 Nov 2008

Understanding how oxidative stress impairs endothelial progenitor cell function may lead to antioxidant therapy to prevent cardiovascular disease

Although its been over a decade since endothelial progenitor cells or EPCs, cells that circulate in the blood repairing and replacing the cells that line blood vessels, were identified, the field is still evolving. EPCs are now being studied as biomarkers to assess the risk of future cardiovascular disease and as potential agents for vascular regeneration.

25 Nov 2008

Metabolex announces positive results from phase 2 trial of MBX-8025

The Phase 2 study was a randomized, double-blind, placebo-controlled clinical trial evaluating the safety and efficacy of MBX-8025, both alone and in combination with atorvastatin (marketed as Lipitor(R)), over an 8-week treatment period.

19 Nov 2008

High Cholesterol News and Research

Even moderate exercise helps breast cancer recovery

Resting pulse predicts heart attacks in women

Statins may treat cerebral cavernous malformation

Researchers identify compound that frees trapped cholesterol

Scientists discover a compound that gets rid of excess cholesterol

Inflammation worsens danger due to atherosclerosis

Athletes aren't necessarily off the hook when it comes to health risks

Innovative brain-scan technology helps visualize brain aging before symptoms appear

Two common biomarkers help predict stroke risk

Patients with skin disease psoriasis need evaluation of coronary artery disease risk

Drug eluting stents provide better outcomes that bare metal stents in angioplasty

Single letter in the human genome points to risk for high cholesterol

Hospitals using quality improvement program increase compliance to stroke treatment guidelines

Psoriasis sufferers more likely to have higher levels of leptin

Nuts and Mediterranean diet appear to help metabolic syndrome

Scientists find 12 new genes with potential as drug targets

Coronary CTA is a low cost, non-invasive alternative for evaluating coronary artery disease

Presence of gum disease may help dentists and physicians identify risk of cardiovascular disease

Understanding how oxidative stress impairs endothelial progenitor cell function may lead to antioxidant therapy to prevent cardiovascular disease

Metabolex announces positive results from phase 2 trial of MBX-8025

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