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Scientists discover novel drug candidate to treat breast cancer, lung cancer and melanoma

Using a new approach, scientists at The Scripps Research Institute and collaborating institutions have discovered a novel drug candidate that could be used to treat certain types of breast cancer, lung cancer and melanoma.

10 Mar 2016

Bioengineers introduce CORDA algorithm to find new therapeutic targets for cancer

Rice University bioengineers have introduced a fast computational method to model tissue-specific metabolic pathways. Their algorithm may help researchers find new therapeutic targets for cancer and other diseases.

10 Mar 2016

Thermo Fisher exhibits new UHPLC-MS workflow solutions for biopharmaceutical characterization at Pittcon 2016

Biopharmaceutical companies can now achieve advanced levels of specificity, sensitivity and speed with specialized analytical workflow solutions for the characterization and quantification of proteins.

From Thermo Fisher Scientific Inc. 9 Mar 2016

Johns Hopkins Greenberg Bladder Cancer Institute awards grants for 10 bladder cancer research projects

A study of obesity and related metabolic changes on bladder cancer incidence and deaths, and a plan to use stem cells to grow novel urinary tubes are among 10 research projects awarded funding by the Johns Hopkins Greenberg Bladder Cancer Institute.

7 Mar 2016

Study on DNA scrunching may aid in developing new antimicrobial medicines

A research collaboration that combines novel "big-data" informatics tools with expertise in basic biology has uncovered details of an essential process in life: how a crucial enzyme locates the site on DNA where it begins to direct the synthesis of RNA. This finding may aid in the discovery of new antimicrobial medicines, and the powerful technological approaches developed for this research may shed light on other essential cellular processes.

4 Mar 2016

Lewin-Cameron Laboratory at Doherty Institute selects OpenSpecimen system to manage biospecimens inventory

In the short time that AXT have been promoting OpenSpecimen, the bioinformatics platform for managing biospecimens inventory developed by Krishagni Solutions in conjunction with the National Cancer Institute, it has generated large amounts of interest in Australia.

From AXT Pty Ltd 2 Mar 2016

Researchers investigate effect of naturally-derived pigment ASX on hippocampal function

With the recent rise in popularity of naturally-derived supplements to maintain a healthy body, there has been a great deal of attention toward development of the so-called "brain foods", which can enhance brain function. Of particular importance is the natural red pigment astaxanthin (ASX) abundant in both salmon and in crustaceans such as shrimp and crab.

22 Feb 2016

New semi-automated sample method facilities extraction of urine samples for LC-MS/MS analysis

INTEGRA, in conjunction with DPX Labs LLC, has produced an application note that describes a novel high throughput semi-automated sample method for processing urine samples ready for drugs of abuse analysis by LC-MS/MS.

From INTEGRA Biosciences 19 Feb 2016

Anti-biofilm compounds show promise against drug-resistant bacteria associated with hospital-acquired infections

Researchers at the University of Michigan Life Sciences Institute and School of Public Health have discovered a new class of anti-biofilm compounds derived from marine microorganisms that show promise against a drug-resistant bacterium commonly associated with hospital-acquired infections.

16 Feb 2016

BD CLiC System launched during 2016 AGBT Meeting

BD (Becton, Dickinson and Company), a leading global medical technology company, today announced the launch of the BD CLiC System during the 2016 Advances in Genome Biology and Technology Meeting.

14 Feb 2016

Silicon Biosystems Menarini, Macrogen to jointly develop genomic cancer tests

Silicon Biosystems Menarini and Macrogen, Inc. today announced they will form a partnership to provide clinical assays and innovative procedures for precision medicine in cancer.

12 Feb 2016

TSRI scientists develop new screening device for drug discovery

Screening large "libraries" of compounds to find those with a desired biological activity is a powerful method for discovering new drugs, but requires a large, expensive and dedicated facility. Now, scientists at the Florida campus of The Scripps Research Institute have devised the central component of a screening system that would be orders of magnitude smaller and cheaper.

11 Feb 2016

New personalized DNA-based digital assay has potential to dramatically impact CML management

The outcomes of chronic myeloid leukemia (CML) have dramatically improved as the result of tyrosine kinase inhibitor (TKI) treatment. Use of a TKI regimen can lower the blood CML biomarker to levels imperceptible by current detection methods. For patients in "molecular remission," however, uncertainties remain regarding whether they will relapse or if treatment should be discontinued.

8 Feb 2016

VolitionRx initiates study to assess NuQ blood tests for detection of prostate cancer

VolitionRx Limited today announced that it has initiated a study to assess the feasibility of using the Company’s NuQ blood tests to detect prostate cancer. The study is in collaboration with the Surrey Cancer Research Institute of the University of Surrey in the UK.

5 Feb 2016

Screening of protein-based pharmaceuticals, free webinar

PANalytical, the world’s leading supplier of analytical instrumentation and software for X-ray and related techniques, announces their free webinar on The power of powder - Screening of protein-based pharmaceuticals on 18 February 2016, presented by Irene Margiolaki, assistant professor at the Department of Biology of the University of Patras, Greece and Detlef Beckers, Lead Scientist XRD, PANalytical B.V., The Netherlands

3 Feb 2016

Framework for improving chemical hazard assessment without animals

A new paper published in Regulatory Toxicology and Pharmacology, co-authored by the Physicians Committee for Responsible Medicine, calls for ongoing development and regulatory acceptance of adverse outcome pathways (AOPs), a framework for improving chemical hazard assessment by prioritizing modern test methods that reduce animal use.

31 Jan 2016

High Throughput News and Research

Scientists discover novel drug candidate to treat breast cancer, lung cancer and melanoma

Bioengineers introduce CORDA algorithm to find new therapeutic targets for cancer

Thermo Fisher exhibits new UHPLC-MS workflow solutions for biopharmaceutical characterization at Pittcon 2016

Johns Hopkins Greenberg Bladder Cancer Institute awards grants for 10 bladder cancer research projects

Study on DNA scrunching may aid in developing new antimicrobial medicines

Lewin-Cameron Laboratory at Doherty Institute selects OpenSpecimen system to manage biospecimens inventory

Researchers investigate effect of naturally-derived pigment ASX on hippocampal function

New semi-automated sample method facilities extraction of urine samples for LC-MS/MS analysis

Anti-biofilm compounds show promise against drug-resistant bacteria associated with hospital-acquired infections

BD CLiC System launched during 2016 AGBT Meeting

Silicon Biosystems Menarini, Macrogen to jointly develop genomic cancer tests

TSRI scientists develop new screening device for drug discovery

New personalized DNA-based digital assay has potential to dramatically impact CML management

VolitionRx initiates study to assess NuQ blood tests for detection of prostate cancer

Screening of protein-based pharmaceuticals, free webinar

Framework for improving chemical hazard assessment without animals

University of Leicester researchers publish structural details of protein linked to many types of cancer

Automated OpenSPR-XT will accelerate discoveries in protein science

New method helps generate cardiac cells for heart disease studies, drug discovery

TSRI researchers develop new technique for modifying complex drug molecules

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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