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Venatorx and GARDP collaborate to accelerate development of new antibiotic

Venatorx Pharmaceuticals and the Global Antibiotic Research and Development Partnership (GARDP) today announced a collaboration to accelerate the development of, and access to, cefepime-taniborbactam (formerly cefepime/VNRX-5133).

29 Apr 2020

Breakthrough study shows liquid biopsy test can safely detect 26 undiagnosed cancers

Results from a first-of-its-kind study of a multicancer blood test in more than 9,900 women with no evidence or history of cancer showed the liquid biopsy test safely detected 26 undiagnosed cancers, enabling potentially curative treatment.

29 Apr 2020

A new platform to create drugs for people with hard-to-treat cancers

A new round of support will help a Purdue University-affiliated startup further develop a platform designed to create drugs for people with hard-to-treat cancers.

29 Apr 2020

Epivax and Entos Pharmaceuticals to develop DNA-based vaccine for COVID-19

Entos Pharmaceuticals (Entos), a healthcare biotechnology company that develops next generation nucleic acid medicines using the Fusogenix drug delivery platform, today announced a collaboration with EpiVax, Inc. (EpiVax), a world leading informatics and immunology biotechnology company with a proven track record in vaccine development.

28 Apr 2020

India's Serum Institute gears up to make millions of doses of potential COVID-19 vaccine

The Serum Institute of India plans to start manufacturing Oxford University's COVID-19 vaccine in 3 weeks to get a head start on production, the company announced. This comes even as experts warn that any successful vaccine will take two or more years to come on the market.

28 Apr 2020

Patients with aggressive form of skin cancer can benefit from new type of immunotherapy

In what is believed to be a first-of-its-kind study to evaluate the safety of a type of immunotherapy before surgery in patients with an aggressive form of skin cancer, researchers report that the treatment eliminated pathologic evidence of cancer in nearly half of the study participants undergoing surgery.

27 Apr 2020

Study: Combination of melanoma drugs prevents cancer from growing or spreading

A first-of-its-kind randomized clinical trial offers strong and perhaps surprising evidence that a combination of two targeted melanoma drugs when given continuously keeps patients' cancer from growing or spreading longer when compared with intermittent treatment, according to study results to be presented at the 2020 virtual annual meeting of the American Association for Cancer Research.

27 Apr 2020

Talazoparib did not show overall survival benefit in patients with advanced BRCA-mutated breast cancer

New data from the Phase III EMBRACA trial led by researchers at The University of Texas MD Anderson Cancer Center found the PARP inhibitor talazoparib did not demonstrate a statistically significant overall survival (OS) benefit for patients with metastatic HER2-negative breast cancer and mutations in the BRCA1/2 genes.

27 Apr 2020

Study can serve as basis for developing new approaches for obesity, diabetes

In the 21st century, the search for methods of treating noncommunicable diseases, such as obesity, metabolic syndrome, and diabetes are among the top priorities.

24 Apr 2020

Combination therapy boosts the immune system's appetite for cancer

A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission, a new study led by UT Southwestern scientists suggests.

24 Apr 2020

The Latest Electron Paramagnetic Resonance (EPR) Spectroscopy Technology

In this interview, Kalina Ranguelova, Senior EPR Application Scientist at Bruker BioSpin, discusses the newest member of benchtop EPS spectrometers family, the Magnettech ESR 5000.

From Bruker BioSpin Division 22 Apr 2020

Researchers uncover how cancer cells don their invisibility cloaks

Immunotherapy drugs that target a protein called programmed death ligand 1 (PD-L1) on the surface of cancer cells have quickly become a mainstay to treat many forms of cancer, often with dramatic results. But exactly how cancer cells turn on this protein was not completely understood.

22 Apr 2020

New database of 14,000 known macrolactones could support drug discovery and research

Researchers from North Carolina State University and Collaborations Pharmaceuticals have created a free-to-use database of 14,000 known macrolactones - large molecules used in drug development - which contains information about the molecular characteristics, chemical diversity and biological activities of this structural class.

22 Apr 2020

Analysis reveals cocktail of pharmaceuticals in the waters of Bangladesh

In spring of 2019, researchers set out to investigate what chemicals could be found in the waters of Bangladesh.

20 Apr 2020

Wavelength Pharmaceuticals expands supplies of key drug ingredients for critically ill COVID-19 patients

Wavelength Pharmaceuticals, a leading supplier of active pharmaceutical ingredients, today reported that it has greatly expanded production of APIs for certain pharmaceutical products needed to manage respiratory critical care patients.

20 Apr 2020

Amid pandemic, FDA seizes cheaper drugs from Canada

The Food and Drug Administration in the past month has stepped up seizures of prescription drugs being sent to American customers from pharmacies in Canada and other countries, according to operators of stores in Florida that facilitate the transactions.

20 Apr 2020

KHN’s ‘What the Health?’: How will we reopen the economy?

President Donald Trump wants to reopen the country soon. But public health experts from across the ideological spectrum insist that won't be safe until the country can dramatically ramp up testing and contact tracing stemming from those infected.

16 Apr 2020

With federal nod, consumers could lose the boost they get from drug ‘coupons’

Patients who get financial help from drug companies to cover their copayments for prescription drugs could owe a bigger chunk of their costs under a proposed federal rule.

16 Apr 2020

Tarantula venom could be used as a potent pain reliever

Pain relief has come a long way, with many medicines developed to ease pain and promote comfort. Previous research has shown that venom can be a potent pain reliever. Snake venom has been widely studied as a potential source of pain relievers, especially for chronic and debilitating pain. Now, a team of scientists has found that spider venom, particularly from Tarantulas, could be used as a potent pain reliever for various conditions.

14 Apr 2020

The race is on for a coronavirus vaccine, 70 candidates, 3 at human trial stage

Amid the coronavirus disease (COVID-19) global pandemic that is infecting millions of people across the globe, hope sparks as the World Health Organization (WHO) reports that seventy vaccination trials for the novel coronavirus are underway, with three already at the human trial stage.

14 Apr 2020