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UCI-led study uncovers how APOBEC3B protein could protect cells against RNA viruses

A new University of California, Irvine-led study uncovers how a protein, APOBEC3B, could protect cells against many different types of RNA viruses like respiratory syncytial virus (RSV), SARS-CoV2, influenza virus, poliovirus and measles, helping to prevent disease.

22 Feb 2023

Researchers estimate the environmental impacts of prostate MRI and biopsy

A Yale-led study examines the potential environmental benefits of more carefully selecting patients for prostate biopsy in a way that can also spare low-yield and potentially harmful procedures.

22 Feb 2023

NYU Long Island School of Medicine attains full accreditation

The Liaison Committee on Medical Education has granted NYU Long Island School of Medicine full accreditation.

22 Feb 2023

Frail patients who are connected to resources less likely to die one year after surgery

New research published today in JAMA Surgery shows that when frail patients are connected to resources, including conversations with a physician about possible outcomes and help preparing their body for surgery, they are less likely to die one year after surgery.

22 Feb 2023

Study may elucidate metformin's potential role in longevity through DNA methylation

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 3, entitled, "Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity."

22 Feb 2023

New machine-learning statistical model may be able to predict COVID-19 resistance

Researchers from Johns Hopkins Medicine and The Johns Hopkins University have created and preliminarily tested what they believe may be one of the first models for predicting who has the highest probability of being resistant to COVID-19 in spite of exposure to SARS-CoV-2, the virus that causes it.

22 Feb 2023

Safety of a gene therapy to treat alpha 1-antitrypsin deficiency

Researchers report on the safety of a gene therapy to treat the common autosomal recessive hereditary disorder alpha 1-antitrypsin (AAT) deficiency in a new article in the peer-reviewed journal Human Gene Therapy.

22 Feb 2023

Scientific advice on the terminal sterilization of oligonucleotide drug products

A new report, coauthored by several major pharmaceutical companies, reviews the current state of sterile oligonucleotide drug product processing.

22 Feb 2023

First phase I trial of intravenous mistletoe extract to treat advanced cancer

Mistletoe extract has been widely used to support cancer therapy and improve quality of life, but there has been a lack of clinical trials and data to support its use.

22 Feb 2023

Scientists identify mechanisms underlying autoimmunity in Down syndrome

Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome.

22 Feb 2023

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

For the first time, humans with newly diagnosed Type 1 diabetes, or T1D, have received two treatments called GABA and GAD that have shown promise in animal studies and in isolated human pancreas islets. This investigator-initiated clinical trial, published in Nature Communications, focused exclusively on children with recent onset T1D.

22 Feb 2023

Study links obesity with 21 Alzheimer's disease-related genes

In a new study, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) link obesity with 21 Alzheimer's disease-related genes, providing a potential mechanistic explanation for why Alzheimer's is sometimes more frequent among adults who experienced obesity in midlife.

22 Feb 2023

Association between sleep disorders and sleep-wake disturbance with MACE or all-cause mortality in the post-stroke population

Researchers assessed the association between post-stroke sleep disturbances and recurrent cardiovascular events.

22 Feb 2023

Medicine News and Research

UCI-led study uncovers how APOBEC3B protein could protect cells against RNA viruses

Researchers estimate the environmental impacts of prostate MRI and biopsy

NYU Long Island School of Medicine attains full accreditation

Frail patients who are connected to resources less likely to die one year after surgery

Study may elucidate metformin's potential role in longevity through DNA methylation

New machine-learning statistical model may be able to predict COVID-19 resistance

Safety of a gene therapy to treat alpha 1-antitrypsin deficiency

Scientific advice on the terminal sterilization of oligonucleotide drug products

First phase I trial of intravenous mistletoe extract to treat advanced cancer

Scientists identify mechanisms underlying autoimmunity in Down syndrome

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

Study links obesity with 21 Alzheimer's disease-related genes

Association between sleep disorders and sleep-wake disturbance with MACE or all-cause mortality in the post-stroke population

Mount Sinai study sheds new light on the role of DNA methylation in Alzheimer's disease

Preconception diabetes and prediabetes associated with increased risk of preterm birth

How are adverse childhood events and less than ideal cardiovascular health in adulthood associated?

Women who have quality relationships less likely to develop multiple chronic conditions in older age

Home healthcare clinics provide better end-of-life care than general hospitals, study shows

First smart wearable device tracks how much people use their voices

Specific group of COVID-19 patients benefits the most from remdesivir, new analysis shows

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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