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Cryo-EM reveals key atomic structures of the ends of actin filament

Actin filaments - protein structures critical to living movement from single cells to animals - have long been known to have polarity associated with their physical characteristics, with growing "barbed" and shrinking "pointed" ends.

8 Jun 2023

Study analyzes the prevalence of osteoporosis in postmenopausal women

Osteoporosis is a degenerative, debilitating bone disease that is increasingly prevalent in postmenopausal women.

8 Jun 2023

New process can help to design drugs with fewer or no side effects

Have you ever wondered how drugs reach their targets and achieve their function within our bodies? If a drug molecule or a ligand is a message, an inbox is typically a receptor in the cell membrane.

7 Jun 2023

ATTR amyloidosis cardiomyopathy can be reversed, study reports

Three men who had heart failure caused by the build-up of sticky, toxic proteins are now free of symptoms after their condition spontaneously reversed in an unprecedented case described by a team at UCL (University College London) and the Royal Free Hospital.

7 Jun 2023

Life-changing procedure using new aortic valve device clears way for patient in need of liver transplant and hip replacement

Janice Couch, 62, a retired pre-school teacher from Grand Rapids, Michigan, is finally physically ready to receive two procedures that stand to change her life, thanks to Henry Ford Health interventional cardiologists who paved the way by implanting a new aortic valve device for the first time in the health system's history.

6 Jun 2023

$Study finds fewer fractures in pre-term and low birthweight infants than normal newborns$

Study finds fewer fractures in pre-term and low birthweight infants than normal newborns

Pre-term and low birthweight infants have fewer fractures in childhood than full-term and normal-weight newborns, according to a new a study from the University of Eastern Finland and Kuopio University Hospital.

6 Jun 2023

Fred Hutch experts highlight research on cancer treatment advances, survivorship and precision oncology at ASCO

At the 2023 American Society for Clinical Oncology Annual Meeting—to be held June 2-6 in Chicago, Illinois—Fred Hutchinson Cancer Center experts will present research spanning survivorship, advances in treatments and clinical trials, how access to cancer care affects outcomes, integrative medicine and more.

5 Jun 2023

Cutting free flu jabs for 50-64-year-olds and mpox vaccines could lead to future strains on the NHS, says expert

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5 Jun 2023

Research opens door to new, more efficient drug combinations for acute myeloid leukemia

Acute myeloid leukemia (AML) is a very aggressive disease in which cells proliferate abnormally, invading the bone marrow and interfering with normal blood cell production. It is the most common acute leukemia in adults with the worst prognosis.

5 Jun 2023

Study shows humans may have evolved a spring-like arch to help us walk on two feet

A recent study hypothesized that the arch recoils to propel the COM, which affects the ankle posture.

2 Jun 2023

Real-world management and outcomes of U.S. patients treated with BpaL for rifampin-resistant tuberculosis

Researchers reported on the treatment of rifampin-resistant tuberculosis in the United States using the FDA approved bedaquiline, pretomanid, and linezolid (BPaL) therapy.

1 Jun 2023

NIH scientists identify genomic variants that cause rare inflammatory skin disorder

Researchers at the National Institutes of Health and their colleagues have identified genomic variants that cause a rare and severe inflammatory skin disorder, known as disabling pansclerotic morphea, and have found a potential treatment.

31 May 2023

AI interpretations of MRI images could provide more accurate RA prediction

Early inflammatory arthritis is often undifferentiated, but it may develop into established RA or another arthropathy.

31 May 2023

Lipid-degrading enzyme, fatty acid amide hydrolase is a predictor of long-term survival in patients with breast cancer

Scientists have identified a lipid-degrading enzyme as a prognostic biomarker for luminal breast cancer.

31 May 2023

The immunopathology of post-acute sequelae of SARS-CoV-2 infection: highlighting the knowledge gaps

The immunopathology of post-acute sequelae of SARS-CoV-2 infection (PASC).

31 May 2023

ENDO 2023 news conferences to highlight latest research in diabetes, obesity, reproductive health

Researchers will delve into the latest research in diabetes, obesity, reproductive health and other aspects of endocrinology during the Endocrine Society's ENDO 2023 news conferences June 15-18.

30 May 2023

Treatment with luspatercept improves red blood cell counts in patients with myelodysplastic syndromes

Treatment with luspatercept improved red blood cell counts and erythroid responses compared to treatment with epoetin alfa in patients with myelodysplastic syndromes (MDS), allowing the majority to no longer require regular blood transfusions.

26 May 2023

Addressing sexual health issues of breast cancer patients on endocrine therapy

Breast cancer treatments that can save a woman's life can seriously harm her sexual health, says Dr. Kristin E. Rojas, a breast cancer surgeon at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine.

26 May 2023

Tumors in distant organs remotely reprogram the liver

Cancers often release molecules into the bloodstream that pathologically alter the liver, shifting it to an inflammatory state, causing fat buildup and impairing its normal detoxifying functions, according to a study from investigators at Weill Cornell Medicine.

25 May 2023

IV plus PA corticosteroids may improve key indicators of functional recovery after total knee arthroplasty

For patients undergoing total knee arthroplasty (TKA), a combination of intravenous and periarticular corticosteroids does not improve pain control – but, may improve key indicators of functional recovery in the days after surgery, reports a trial in The Journal of Bone & Joint Surgery.

25 May 2023

Bone News and Research

Cryo-EM reveals key atomic structures of the ends of actin filament

Study analyzes the prevalence of osteoporosis in postmenopausal women

New process can help to design drugs with fewer or no side effects

ATTR amyloidosis cardiomyopathy can be reversed, study reports

Life-changing procedure using new aortic valve device clears way for patient in need of liver transplant and hip replacement

Study finds fewer fractures in pre-term and low birthweight infants than normal newborns

Fred Hutch experts highlight research on cancer treatment advances, survivorship and precision oncology at ASCO

Cutting free flu jabs for 50-64-year-olds and mpox vaccines could lead to future strains on the NHS, says expert

Research opens door to new, more efficient drug combinations for acute myeloid leukemia

Study shows humans may have evolved a spring-like arch to help us walk on two feet

Real-world management and outcomes of U.S. patients treated with BpaL for rifampin-resistant tuberculosis

NIH scientists identify genomic variants that cause rare inflammatory skin disorder

AI interpretations of MRI images could provide more accurate RA prediction

Lipid-degrading enzyme, fatty acid amide hydrolase is a predictor of long-term survival in patients with breast cancer

The immunopathology of post-acute sequelae of SARS-CoV-2 infection: highlighting the knowledge gaps

ENDO 2023 news conferences to highlight latest research in diabetes, obesity, reproductive health

Treatment with luspatercept improves red blood cell counts in patients with myelodysplastic syndromes

Addressing sexual health issues of breast cancer patients on endocrine therapy

Tumors in distant organs remotely reprogram the liver

IV plus PA corticosteroids may improve key indicators of functional recovery after total knee arthroplasty

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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