Endocrine News and Research

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Investigational drug abaloparatide-SC may help increase bone mineral density in postmenopausal women

The investigational drug abaloparatide-SC (subcutaneous) may help increase bone mineral density in postmenopausal women and reduce their risk of fracture, new industry-sponsored research suggests. The results of the subgroup analysis within the ACTIVE clinical trial will be presented Friday, April 1, at ENDO 2016, the annual meeting of the Endocrine Society in Boston.

4 Apr 2016

BMI measurement can help pediatricians identify infants at higher risk of early-childhood obesity

Pediatricians can now identify infants who are at higher risk of early-childhood obesity, before obesity develops, using a simple measurement of body mass index (BMI), a tool not routinely used until children are 2 years old.

2 Apr 2016

European Obesity Day to focus on growing obesity epidemic

The growing obesity epidemic, which is predicted to affect more than half of all European citizens by 2030, will be the focus of European Obesity Day to be held on 21 May.

25 Mar 2016

Endocrine Society issues recommendations to improve care for people with diabetes

To provide integrated care for people who have diabetes and may be at risk of developing related medical complications, the U.S. health care system needs to continue building effective multidisciplinary care team models, according to new recommendations issued by the Endocrine Society today.

23 Mar 2016

FDA announces required class-wide safety labeling changes for IR opioid pain medications

In a continuing effort to educate prescribers and patients about the potential risks related to opioid use, the U.S. Food and Drug Administration today announced required class-wide safety labeling changes for immediate-release (IR) opioid pain medications. Among the changes, the FDA is requiring a new boxed warning about the serious risks of misuse, abuse, addiction, overdose and death.

23 Mar 2016

Exposure to substitute chemical can stimulate formation of fat cells

Exposure to a substitute chemical often used to replace bisphenol A in plastics can encourage the formation of fat cells, according to a new study published in the Endocrine Society's journal Endocrinology.

23 Mar 2016

Decreased dietary diversity linked to reduced microbiotic richness

Changes in farming practices over the last 50 years have resulted in decreased agro-diversity which, in turn, has resulted in decreased dietary diversity. The significant impact of this change in dietary richness on human health is the topic of an insightful perspective in Molecular Metabolism by Mark Heiman, MicroBiome Therapeutics and Frank Greenway, Pennington Biomedical Research Center

15 Mar 2016

Alcohol consumption may increase risk for breast cancer

A University of Houston researcher and his team have discovered an important link between alcohol and breast cancer by identifying a cancer-causing gene triggered by alcohol

15 Mar 2016

New development offers hope to patients with inoperable advanced midgut neuroendocrine cancer

A novel drug proven to reduce the risk of disease progression by 79% as well as three new European Centres of Excellence, offer new hope to patients with inoperable metastatic advanced midgut neuroendocrine cancer.

11 Mar 2016

New FDA approval expands use of AstraZeneca's Faslodex for women with HR+, HER2- metastatic breast cancer

AstraZeneca today announced that the US Food and Drug Administration has approved a new indication in the US, expanding the use of Faslodex (fulvestrant) to include use in combination with Ibrance (palbociclib).

7 Mar 2016

New findings about prostate cells may identify future strategies for treating aggressive prostate cancer

A study that revealed new findings about prostate cells may point to future strategies for treating aggressive and therapy-resistant forms of prostate cancer.

1 Mar 2016

Pfizer’s IBRANCE (palbociclib) now approved for use in women with HR+, HER2- metastatic breast cancer

Pfizer Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved a new indication expanding the use of IBRANCE (palbociclib) 125mg capsules, Pfizer’s metastatic breast cancer therapy.

23 Feb 2016

Intestinal microbiota necessary for optimum postnatal growth

The intestinal microbiota is necessary to ensure optimum postnatal growth and contributes to determining the size of adult individuals, notably in the event of undernutrition.

22 Feb 2016

Exocrine tissue could play a role in diabetes treatment

Diabetes describes a disease where the body is not receiving a sufficient supply of insulin. It commonly inflicts the pancreas, the organ responsible for insulin production. More specifically, it inflicts the cells that produce insulin, which are found in the endocrine tissue of the pancreas.

22 Feb 2016

Genetic test use rises in young US breast cancer patients

BRCA testing is becoming more common in women diagnosed with breast cancer by the age of 40 years in the USA, research shows, with concerns about genetic risk influencing surgical decisions.

18 Feb 2016

Beiging of white fat could be harnessed to combat diabetes

Researchers are getting closer to learning how to turn white fat cells into brown fat cells, in a process called "beiging," to bring down blood sugar levels and fight diabetes. The team, led by Joseph Baur, PhD, an assistant professor of Physiology in the Perelman School of Medicine at the University of Pennsylvania published their findings this month in the journal Diabetes.

18 Feb 2016

New optogenetic technology could turn on immune cells to attack melanoma tumors

A new optogenetic technology developed at UMass Medical School, called optogenetic immunomodulation, is capable of turning on immune cells to attack melanoma tumors in mice. Using near-infrared light, UMMS researchers have shown they can selectively activate an immune response by controlling the flow of calcium ions into the cell. This breakthrough could lead to less invasive, and more controlled and selective, immunotherapies for cancer treatment.

17 Feb 2016

Beige-fat formation could be harnessed to fight diabetes

Researchers are getting closer to learning how to turn white fat cells into brown fat cells, in a process called "beiging," to bring down blood sugar levels and fight diabetes.

17 Feb 2016

Proton beam therapy safe for treating childhood brain cancer medulloblastoma

Proton beam therapy--a more precise form of radiotherapy--to treat the childhood brain cancer medulloblastoma appears to be as safe as conventional radiotherapy with similar survival rates, according to new research published in The Lancet Oncology journal today.

1 Feb 2016

Study: Prenatal exposure to flame retardants may have lasting effect on child's executive function

New research from the University of Cincinnati College of Medicine suggests that prenatal exposure to flame retardants and perfluoroalkyl substances (PFASs) commonly found in the environment may have a lasting effect on a child's cognitive and behavioral development, known as executive function.

28 Jan 2016

Endocrine News and Research

Investigational drug abaloparatide-SC may help increase bone mineral density in postmenopausal women

BMI measurement can help pediatricians identify infants at higher risk of early-childhood obesity

European Obesity Day to focus on growing obesity epidemic

Endocrine Society issues recommendations to improve care for people with diabetes

FDA announces required class-wide safety labeling changes for IR opioid pain medications

Exposure to substitute chemical can stimulate formation of fat cells

Decreased dietary diversity linked to reduced microbiotic richness

Alcohol consumption may increase risk for breast cancer

New development offers hope to patients with inoperable advanced midgut neuroendocrine cancer

New FDA approval expands use of AstraZeneca's Faslodex for women with HR+, HER2- metastatic breast cancer

New findings about prostate cells may identify future strategies for treating aggressive prostate cancer

Pfizer’s IBRANCE (palbociclib) now approved for use in women with HR+, HER2- metastatic breast cancer

Intestinal microbiota necessary for optimum postnatal growth

Exocrine tissue could play a role in diabetes treatment

Genetic test use rises in young US breast cancer patients

Beiging of white fat could be harnessed to combat diabetes

New optogenetic technology could turn on immune cells to attack melanoma tumors

Beige-fat formation could be harnessed to fight diabetes

Proton beam therapy safe for treating childhood brain cancer medulloblastoma

Study: Prenatal exposure to flame retardants may have lasting effect on child's executive function

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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