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Breakthrough dual-drug hydrogel promotes cartilage repair in osteoarthritis

A research team from Northwest University, China, has developed a breakthrough nano-composite hydrogel system to address the dual challenges of inflammation and cartilage damage in osteoarthritis (OA), a leading cause of joint disability worldwide.

3 Jul 2025

Alzheimer’s protein found to drive lung cancer spread to the brain

Researchers at McMaster University, Cleveland Clinic and Case Comprehensive Cancer Center have uncovered how a protein long associated with Alzheimer's disease helps lung cancer spread to the brain – a discovery that offers hope that existing Alzheimer's drugs could be repurposed in preventing cancer's spread.

3 Jul 2025

Gene therapy brings back hearing in young and adult deaf patients

Gene therapy can improve hearing in children and adults with congenital deafness or severe hearing impairment, a new study involving researchers at Karolinska Institutet reports.

3 Jul 2025

New protein target offers hope for chronic inflammation treatment

Chronic inflammation occurs when the immune system is stuck in attack-mode, sending cell after cell to defend and repair the body for months or even years.

2 Jul 2025

TET2 mutations in blood stem cells linked to lower Alzheimer's risk

A study published in Cell Stem Cell reveals that some mutations in blood stem cells might help protect against late-onset Alzheimer's disease.

2 Jul 2025

Breakthrough AI uncovers promising Rett syndrome treatment

Rett syndrome is a devastating rare genetic childhood disorder primarily affecting girls. Merely 1 out of 10,000 girls are born with it and much fewer boys.

2 Jul 2025

Scientists reveal how chemotherapy causes genetic damage in healthy blood

For the first time, scientists have systematically studied the genetic effects of chemotherapy on healthy tissues.

2 Jul 2025

Aromatic benzaldehyde inhibits growth of therapy-resistant pancreatic cancer

During therapy, some cancer cells evolve to escape elimination. Newer anticancer drugs that can overcome this resistance are necessary.

2 Jul 2025

Healthy lifestyle lowers risk of diverticulitis despite genetic susceptibility

Maintaining a healthy lifestyle-specifically, a diet rich in fibre but light on red/processed meat, regular exercise, not smoking, and sticking to a normal weight-is linked to a significantly lower risk of diverticulitis, finds a large long term study, published online in the journal Gut.

2 Jul 2025

Study enhances the understanding of urolithiasis pathogenesis

A recent study published in Genes & Diseases reveals new insights into the relationship between immune cell characteristics, blood metabolites, and the risk of urolithiasis.

2 Jul 2025

Single-cell transcriptomes of immune cells offer insight into juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA), a type of arthritis commonly occurring in children, is a chronic, inflammatory condition that affects the joints, causing pain, swelling, stiffness, and limiting the range of motion.

2 Jul 2025

Why exercise is key for keeping slim after you quit smoking

Quitting smoking is linked to greater long-term waist circumference gain, but this effect may be due to shared genetics rather than quitting itself. Increased physical activity consistently helped limit waist expansion across all genetic backgrounds.

1 Jul 2025

HIV treatment linked to risk of early knee osteoarthritis

Acquired immune deficiency syndrome, or AIDS, caused by the human immunodeficiency virus (HIV), weakens the body's immune system and can be life-threatening if left untreated.

1 Jul 2025

Breakthrough study reveals killing power of CD4 T cells against cancer

In the fight against cancer, immunotherapy - which aims to boost the body's natural defences against cancer - is experiencing remarkable growth. Most of these treatments are based on CD8 T lymphocytes, ''killer cells'' able to eliminate diseased cells.

1 Jul 2025

Embryos from women with PCOS carry distinctive epigenetic memory

Novel research presented today at the 41st Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) has found that embryos from women with polycystic ovary syndrome (PCOS) carry a distinctive 'epigenetic memory' that could explain why the condition often runs in families.

1 Jul 2025

Shift Bioscience proposes improved ranking system for virtual cell models to accelerate gene target discovery

Shift Bioscience (Shift), a biotechnology company uncovering the biology of cell rejuvenation to develop new therapies for age driven diseases, today announced the results of a new study detailing an improved approach to ranking virtual cell models for gene discovery.

1 Jul 2025

Improving RNA drug delivery through intracellular traffic control

A recent study involving researchers from the University of Basel reveals that slowing down the intracellular transport of RNA-based drugs can significantly enhance their effectiveness.

1 Jul 2025

Cannabis smoking changes your DNA, leaving epigenetic scars

Long-term, persistent weekly or more frequent cannabis smoking leaves a distinct and partially reversible epigenetic footprint on blood DNA. These methylation changes strongly overlap with those from tobacco and may serve as biomarkers of smoke exposure.

30 Jun 2025

Genetic bottlenecks limit the rise of pandemic cholera strains

A new study by the Genomics and Microbial Evolution Group at the Miguel Hernández University of Elche (UMH) together with the Department of Host-Microbe Interactions at St. Jude Children's Research Hospital in Memphis, USA, sheds light on one of the great enigmas of microbiology: why only certain strains of common bacteria become pandemic pathogens.

30 Jun 2025

VIRMA protein regulates brain development by controlling ribosome biogenesis

Ribosomes are tiny molecular machines inside all living cells that build proteins, and ribosome biogenesis is the complex, multi-step process by which they are made.

30 Jun 2025